RUB1 (YDR139C)


Gene profile

Gene name: RUB1
Reference locus (S288C): YDR139C
Gene biotype: protein_coding

Description: NEDD8-like protein RUB1; Ubiquitin-like protein with similarity to mammalian NEDD8; conjugation (neddylation) substrates include the cullins Cdc53p, Rtt101p, and Cul3p; activated by Ula1p and Uba3p (E1 enzyme pair); conjugation mediated by Ubc12p (E2 enzyme)

Top 10 interactors (score): CDC53 (0.998); UBC12 (0.993); UBA3 (0.992); ULA1 (0.992); YUH1 (0.99); SKP1 (0.98); RPL39 (0.976); RPL5 (0.975); RPS3 (0.974); CDC34 (0.971); RPS20 (0.971); RPS31 (0.971); RPS15 (0.97); RPL32 (0.969); RPS2 (0.969); RPL30 (0.968); RPL25 (0.968); RPL38 (0.967); ASC1 (0.967); RPS13 (0.966)

Homologues (species, bitscore): NEDD8 (Homo sapiens, 92.8); Nedd8 (Mus musculus, 92.8); nedd8 (Danio rerio, 91.3); nedd8 (Xenopus tropicalis, 92.0); Nedd8 (Drosophila melanogaster, 92.8); ned-8 (Caenorhabditis elegans, 92.4); RUB1 (Arabidopsis thaliana, 86.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:704553-704859:- gene-YDR139C_AKU4011 rna-NM_001180446.3_AKU4011 cds-NP_010423.4_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000080.1:419980-420286:+ gene-YDR139C_BG1 rna-NM_001180446.3_BG1 cds-NP_010423.4_BG1 99.5 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:736609-736915:- gene-YDR139C_Bruggeman rna-NM_001180446.3_Bruggeman cds-NP_010423.4_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:724581-724887:- gene-YDR139C_CAT1 rna-NM_001180446.3_CAT1 cds-NP_010423.4_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:695591-695897:- gene-YDR139C_CBS1585 rna-NM_001180446.3_CBS1585 cds-NP_010423.4_CBS1585 99.1 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:721494-721800:- gene-YDR139C_CBS436 rna-NM_001180446.3_CBS436 cds-NP_010423.4_CBS436 99.5 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:691943-692249:- gene-YDR139C_CBS6412 rna-NM_001180446.3_CBS6412 cds-NP_010423.4_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:720918-721224:- gene-YDR139C_CBS6413 rna-NM_001180446.3_CBS6413 cds-NP_010423.4_CBS6413 99.1 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:726056-726362:- gene-YDR139C_CENPK1137D rna-NM_001180446.3_CENPK1137D cds-NP_010423.4_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:706315-706621:- gene-YDR139C_EthanolRed rna-NM_001180446.3_EthanolRed cds-NP_010423.4_EthanolRed 99.1 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:713109-713415:- gene-YDR139C_FaliES1 rna-NM_001180446.3_FaliES1 cds-NP_010423.4_FaliES1 99.1 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000002.1:65255-65561:- gene-YDR139C_JAY291 rna-NM_001180446.3_JAY291 cds-NP_010423.4_JAY291 99.5 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:722533-722839:- gene-YDR139C_MUCL30387 rna-NM_001180446.3_MUCL30387 cds-NP_010423.4_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:711552-711858:- gene-YDR139C_MUCL30388 rna-NM_001180446.3_MUCL30388 cds-NP_010423.4_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:696933-697239:- gene-YDR139C_MUCL39482 rna-NM_001180446.3_MUCL39482 cds-NP_010423.4_MUCL39482 99.1 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:634890-635196:- gene-YDR139C_MUCL42920 rna-NM_001180446.3_MUCL42920 cds-NP_010423.4_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:733541-733847:- gene-YDR139C_NCIM3186 rna-NM_001180446.3_NCIM3186 cds-NP_010423.4_NCIM3186 100.0 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:696335-696641:- gene-YDR139C_NCYC1407 rna-NM_001180446.3_NCYC1407 cds-NP_010423.4_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:715673-715979:- gene-YDR139C_PE2H3 rna-NM_001180446.3_PE2H3 cds-NP_010423.4_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:714978-715284:- gene-YDR139C_PE2H4 rna-NM_001180446.3_PE2H4 cds-NP_010423.4_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:733618-733924:- gene-YDR139C_S288C rna-NM_001180446.3_S288C cds-NP_010423.4_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000009.1:82289-82595:- gene-YDR139C_SA1 rna-NM_001180446.3_SA1 cds-NP_010423.4_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:712631-712937:- gene-YDR139C_ThermosaccDry rna-NM_001180446.3_ThermosaccDry cds-NP_010423.4_ThermosaccDry 99.1 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:725987-726293:- gene-YDR139C_VR1 rna-NM_001180446.3_VR1 cds-NP_010423.4_VR1 99.5 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:710212-710518:- gene-YDR139C_ZTW1 rna-NM_001180446.3_ZTW1 cds-NP_010423.4_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:714716-715022:- gene-YDR139C_Sparadoxus rna-NM_001180446.3_Sparadoxus cds-NP_010423.4_Sparadoxus 91.4 100.0 Verified 1 1 1 False True False False False

Additional files