Gene name: RTT109
Reference locus (S288C): YLL002W
Gene biotype: protein_coding
Description: Histone acetyltransferase; critical for cell survival in presence of DNA damage during S phase, required for recovery after DSB repair; acetylates H3K56, H3K9; H3K56 acetylation activity required for expression homeostasis, buffering of mRNA synthesis rate against changes in gene dosage during S phase; involved in non-homologous end joining and regulation of Ty1 transposition; prevents hyper-amplification of rDNA; interacts physically with Vps75p
Top 10 interactors (score): HHT2 (0.999); ASF1 (0.999); VPS75 (0.999); HHT1 (0.999); GCN5 (0.996); RTT106 (0.979); HST3 (0.974); HHF1 (0.967); HST4 (0.962); RTT101 (0.942); HHF2 (0.941); CAC2 (0.933); MMS22 (0.932); RAD52 (0.929); NAP1 (0.91); HTZ1 (0.903); HAT1 (0.882); RLF2 (0.862); RPD3 (0.846); SAS3 (0.845)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:134048-135358:+ | gene-YLL002W_AKU4011 | rna-NM_001181822.1_AKU4011 | cds-NP_013099.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:97480-98790:+ | gene-YLL002W_BG1 | rna-NM_001181822.1_BG1 | cds-NP_013099.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:144165-145475:+ | gene-YLL002W_Bruggeman | rna-NM_001181822.1_Bruggeman | cds-NP_013099.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:144961-146271:+ | gene-YLL002W_CAT1 | rna-NM_001181822.1_CAT1 | cds-NP_013099.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:141647-142957:+ | gene-YLL002W_CBS1585 | rna-NM_001181822.1_CBS1585 | cds-NP_013099.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:132013-133323:+ | gene-YLL002W_CBS436 | rna-NM_001181822.1_CBS436 | cds-NP_013099.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:140419-141729:+ | gene-YLL002W_CBS6412 | rna-NM_001181822.1_CBS6412 | cds-NP_013099.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:141913-143223:+ | gene-YLL002W_CBS6413 | rna-NM_001181822.1_CBS6413 | cds-NP_013099.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:131332-132642:+ | gene-YLL002W_CENPK1137D | rna-NM_001181822.1_CENPK1137D | cds-NP_013099.1_CENPK1137D | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:134069-135379:+ | gene-YLL002W_EthanolRed | rna-NM_001181822.1_EthanolRed | cds-NP_013099.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:133640-134950:+ | gene-YLL002W_FaliES1 | rna-NM_001181822.1_FaliES1 | cds-NP_013099.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000083.1:20423-21733:- | gene-YLL002W_JAY291 | rna-NM_001181822.1_JAY291 | cds-NP_013099.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:141770-143080:+ | gene-YLL002W_MUCL30387 | rna-NM_001181822.1_MUCL30387 | cds-NP_013099.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:146268-147578:+ | gene-YLL002W_MUCL30388 | rna-NM_001181822.1_MUCL30388 | cds-NP_013099.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:142118-143428:+ | gene-YLL002W_MUCL39482 | rna-NM_001181822.1_MUCL39482 | cds-NP_013099.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:141786-143096:+ | gene-YLL002W_MUCL42920 | rna-NM_001181822.1_MUCL42920 | cds-NP_013099.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:146265-147575:+ | gene-YLL002W_NCIM3186 | rna-NM_001181822.1_NCIM3186 | cds-NP_013099.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:133721-135031:+ | gene-YLL002W_NCYC1407 | rna-NM_001181822.1_NCYC1407 | cds-NP_013099.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:140069-141379:+ | gene-YLL002W_PE2H3 | rna-NM_001181822.1_PE2H3 | cds-NP_013099.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:139810-141120:+ | gene-YLL002W_PE2H4 | rna-NM_001181822.1_PE2H4 | cds-NP_013099.1_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:146291-147601:+ | gene-YLL002W_S288C | rna-NM_001181822.1_S288C | cds-NP_013099.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000062.1:49252-50562:+ | gene-YLL002W_SA1 | rna-NM_001181822.1_SA1 | cds-NP_013099.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:134143-135453:+ | gene-YLL002W_ThermosaccDry | rna-NM_001181822.1_ThermosaccDry | cds-NP_013099.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:147743-149053:+ | gene-YLL002W_VR1 | rna-NM_001181822.1_VR1 | cds-NP_013099.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:133471-134781:+ | gene-YLL002W_ZTW1 | rna-NM_001181822.1_ZTW1 | cds-NP_013099.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:141851-143162:+ | gene-YLL002W_Sparadoxus | rna-NM_001181822.1_Sparadoxus | cds-NP_013099.1_Sparadoxus | 88.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |