RTT10 (YPL183C)


Gene profile

Gene name: RTT10
Reference locus (S288C): YPL183C
Gene biotype: protein_coding

Description: Regulator of Ty1 transposition protein 10; WD40 domain-containing protein involved in endosomal recycling; forms a complex with Rrt2p that functions in the retromer-mediated pathway for recycling internalized cell-surface proteins; interacts with Trm7p for 2'-O-methylation of N34 of substrate tRNAs; has a role in regulation of Ty1 transposition; human ortholog is WDR6

Top 10 interactors (score): TRM7 (0.999); TRM82 (0.99); TRM732 (0.984); SPB1 (0.96); RRT2 (0.944); NOG1 (0.942); TRM11 (0.932); PWP2 (0.915); TRM1 (0.904); TRM8 (0.891); RRP12 (0.886); UTP13 (0.876); ARX1 (0.868); UTP8 (0.859); NOC2 (0.858); NOG2 (0.853); PWP1 (0.85); GCD10 (0.849); NCL1 (0.84); DHR2 (0.835)

Homologues (species, bitscore): WDR6 (Homo sapiens, 126.7); Wdr6 (Mus musculus, 126.7); wdr6 (Danio rerio, 128.6); wdr6 (Xenopus tropicalis, 188.0); CG33172 (Drosophila melanogaster, 72.8); Y53C12B.1 (Caenorhabditis elegans, 57.4); AT4G01860 (Arabidopsis thaliana, 99.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:177498-180539:- gene-YPL183C_AKU4011 rna-NM_001183997.1_AKU4011 cds-NP_015142.1_AKU4011 99.0 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000069.1:383109-386150:- gene-YPL183C_BG1 rna-NM_001183997.1_BG1 cds-NP_015142.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:203344-206385:- gene-YPL183C_Bruggeman rna-NM_001183997.1_Bruggeman cds-NP_015142.1_Bruggeman 98.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:199686-202727:- gene-YPL183C_CAT1 rna-NM_001183997.1_CAT1 cds-NP_015142.1_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:181564-184605:- gene-YPL183C_CBS1585 rna-NM_001183997.1_CBS1585 cds-NP_015142.1_CBS1585 99.0 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:196220-199261:- gene-YPL183C_CBS436 rna-NM_001183997.1_CBS436 cds-NP_015142.1_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:186233-189274:- gene-YPL183C_CBS6412 rna-NM_001183997.1_CBS6412 cds-NP_015142.1_CBS6412 99.0 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:177716-180757:- gene-YPL183C_CBS6413 rna-NM_001183997.1_CBS6413 cds-NP_015142.1_CBS6413 99.0 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:199377-202418:- gene-YPL183C_CENPK1137D rna-NM_001183997.1_CENPK1137D cds-NP_015142.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:176240-179281:- gene-YPL183C_EthanolRed rna-NM_001183997.1_EthanolRed cds-NP_015142.1_EthanolRed 99.0 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:183832-186873:- gene-YPL183C_FaliES1 rna-NM_001183997.1_FaliES1 cds-NP_015142.1_FaliES1 99.0 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000007.1:179028-182069:+ gene-YPL183C_JAY291 rna-NM_001183997.1_JAY291 cds-NP_015142.1_JAY291 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:194725-197766:- gene-YPL183C_MUCL30387 rna-NM_001183997.1_MUCL30387 cds-NP_015142.1_MUCL30387 98.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:192745-195786:- gene-YPL183C_MUCL30388 rna-NM_001183997.1_MUCL30388 cds-NP_015142.1_MUCL30388 98.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:174893-177934:- gene-YPL183C_MUCL39482 rna-NM_001183997.1_MUCL39482 cds-NP_015142.1_MUCL39482 99.0 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:231572-234613:- gene-YPL183C_MUCL42920 rna-NM_001183997.1_MUCL42920 cds-NP_015142.1_MUCL42920 99.0 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:199478-202519:- gene-YPL183C_NCIM3186 rna-NM_001183997.1_NCIM3186 cds-NP_015142.1_NCIM3186 98.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:181345-184386:- gene-YPL183C_NCYC1407 rna-NM_001183997.1_NCYC1407 cds-NP_015142.1_NCYC1407 99.0 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:188787-191828:- gene-YPL183C_PE2H3 rna-NM_001183997.1_PE2H3 cds-NP_015142.1_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:188430-191471:- gene-YPL183C_PE2H4 rna-NM_001183997.1_PE2H4 cds-NP_015142.1_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:199495-202536:- gene-YPL183C_S288C rna-NM_001183997.1_S288C cds-NP_015142.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000012.1:170810-173851:+ gene-YPL183C_SA1 rna-NM_001183997.1_SA1 cds-NP_015142.1_SA1 99.1 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:183630-186671:- gene-YPL183C_ThermosaccDry rna-NM_001183997.1_ThermosaccDry cds-NP_015142.1_ThermosaccDry 99.0 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:198560-201601:- gene-YPL183C_VR1 rna-NM_001183997.1_VR1 cds-NP_015142.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:182959-186000:- gene-YPL183C_ZTW1 rna-NM_001183997.1_ZTW1 cds-NP_015142.1_ZTW1 99.0 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:184570-187611:- gene-YPL183C_Sparadoxus rna-NM_001183997.1_Sparadoxus cds-NP_015142.1_Sparadoxus 87.5 99.9 Verified 1 1 1 False True False False False

Additional files