RTP1 (YMR185W)


Gene profile

Gene name: RTP1
Reference locus (S288C): YMR185W
Gene biotype: protein_coding

Description: RNA polymerase II assembly factor RTP1; Protein required for the nuclear import and biogenesis of RNA pol II; conflicting evidence on whether null mutant is viable with elongated buds, or inviable; interacts with Rpb2, Rpb3, Nup116p, Nup100p and components of the R2TP complex (Rvb1p, Rvb2p, Pih1p); similar to human TMCO7 gene

Top 10 interactors (score): NAT3 (0.962); YAR1 (0.699); RPN2 (0.681); BLM10 (0.641); RPN1 (0.615); UTP4 (0.589); PRE2 (0.571); RPN5 (0.55); ENP2 (0.54); TPD3 (0.48); DHR2 (0.478); RBK1 (0.465); SGD1 (0.461); RPT6 (0.453); RVB2 (0.451); UTP13 (0.4); IFH1 (0.4)

Homologues (species, bitscore): TANGO6 (Homo sapiens, 73.6); Tango6 (Mus musculus, 64.7); tango6 (Danio rerio, 52.0); tango6 (Xenopus tropicalis, 65.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:668956-671901:+ gene-YMR185W_AKU4011 rna-NM_001182691.1_AKU4011 cds-NP_013910.1_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000068.1:1143-4088:- gene-YMR185W_BG1 rna-NM_001182691.1_BG1 cds-NP_013910.1_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:613172-616117:+ gene-YMR185W_Bruggeman rna-NM_001182691.1_Bruggeman cds-NP_013910.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:615917-618862:+ gene-YMR185W_CAT1 rna-NM_001182691.1_CAT1 cds-NP_013910.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:601212-604157:+ gene-YMR185W_CBS1585 rna-NM_001182691.1_CBS1585 cds-NP_013910.1_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:605476-608421:+ gene-YMR185W_CBS436 rna-NM_001182691.1_CBS436 cds-NP_013910.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:712771-715716:+ gene-YMR185W_CBS6412 rna-NM_001182691.1_CBS6412 cds-NP_013910.1_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:600361-603306:+ gene-YMR185W_CBS6413 rna-NM_001182691.1_CBS6413 cds-NP_013910.1_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:623604-626549:+ gene-YMR185W_CENPK1137D rna-NM_001182691.1_CENPK1137D cds-NP_013910.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:661401-664346:+ gene-YMR185W_EthanolRed rna-NM_001182691.1_EthanolRed cds-NP_013910.1_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:607057-610002:+ gene-YMR185W_FaliES1 rna-NM_001182691.1_FaliES1 cds-NP_013910.1_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000265.1:1058-4003:- gene-YMR185W_JAY291 rna-NM_001182691.1_JAY291 cds-NP_013910.1_JAY291 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:606718-609663:+ gene-YMR185W_MUCL30387 rna-NM_001182691.1_MUCL30387 cds-NP_013910.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:613498-616443:+ gene-YMR185W_MUCL30388 rna-NM_001182691.1_MUCL30388 cds-NP_013910.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:602284-605229:+ gene-YMR185W_MUCL39482 rna-NM_001182691.1_MUCL39482 cds-NP_013910.1_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:609617-612562:+ gene-YMR185W_MUCL42920 rna-NM_001182691.1_MUCL42920 cds-NP_013910.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:628979-631924:+ gene-YMR185W_NCIM3186 rna-NM_001182691.1_NCIM3186 cds-NP_013910.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:601936-604881:+ gene-YMR185W_NCYC1407 rna-NM_001182691.1_NCYC1407 cds-NP_013910.1_NCYC1407 99.2 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:611805-614750:+ gene-YMR185W_PE2H3 rna-NM_001182691.1_PE2H3 cds-NP_013910.1_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:612791-615736:+ gene-YMR185W_PE2H4 rna-NM_001182691.1_PE2H4 cds-NP_013910.1_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:629025-631970:+ gene-YMR185W_S288C rna-NM_001182691.1_S288C cds-NP_013910.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000002.1:176145-179090:- gene-YMR185W_SA1 rna-NM_001182691.1_SA1 cds-NP_013910.1_SA1 99.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:603183-606128:+ gene-YMR185W_ThermosaccDry rna-NM_001182691.1_ThermosaccDry cds-NP_013910.1_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:616353-619298:+ gene-YMR185W_VR1 rna-NM_001182691.1_VR1 cds-NP_013910.1_VR1 99.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000028.1:18972-21917:+ gene-YMR185W_ZTW1 rna-NM_001182691.1_ZTW1 cds-NP_013910.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:621112-624042:+ gene-YMR185W_Sparadoxus rna-NM_001182691.1_Sparadoxus cds-NP_013910.1_Sparadoxus 86.9 99.4 Verified 1 1 1 False True False False False

Additional files