Gene name: RTN2
Reference locus (S288C): YDL204W
Gene biotype: protein_coding
Description: Reticulon-like protein 2; Reticulon protein; involved in nuclear pore assembly and maintenance of tubular ER morphology; promotes membrane curvature; regulates the ER asymmetry-induced inheritance block during ER stress; role in ER-derived peroxisomal biogenesis; interacts with Sec6p, Yip3p, and Sbh1p; less abundant than RTN1; member of RTNLA (reticulon-like A) subfamily; protein increases in abundance and relocalizes to plasma membrane upon DNA replication stress
Top 10 interactors (score): RTN1 (0.999); DCS2 (0.987); MSC1 (0.983); PHM7 (0.977); YOP1 (0.972); DDR2 (0.962); ALD3 (0.956); SEY1 (0.955); TKL2 (0.955); HBT1 (0.952); SOL4 (0.946); TFS1 (0.943); CTT1 (0.942); FMP16 (0.941); GAD1 (0.941); OM45 (0.94); LNP1 (0.94); PGM2 (0.935); GDB1 (0.932); UIP4 (0.928)
Homologues (species, bitscore): RTN2 (Homo sapiens, 60.5); Rtn2 (Mus musculus, 58.9); rtn3 (Danio rerio, 62.8); rtn4 (Xenopus tropicalis, 66.2); Rtnl1 (Drosophila melanogaster, 58.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:78089-79270:+ | gene-YDL204W_AKU4011 | rna-NM_001180264.1_AKU4011 | cds-NP_010077.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:469396-470577:- | gene-YDL204W_BG1 | rna-NM_001180264.1_BG1 | cds-NP_010077.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:94470-95651:+ | gene-YDL204W_Bruggeman | rna-NM_001180264.1_Bruggeman | cds-NP_010077.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:96592-97773:+ | gene-YDL204W_CAT1 | rna-NM_001180264.1_CAT1 | cds-NP_010077.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:76940-78121:+ | gene-YDL204W_CBS1585 | rna-NM_001180264.1_CBS1585 | cds-NP_010077.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:291846-293027:+ | gene-YDL204W_CBS436 | rna-NM_001180264.1_CBS436 | cds-NP_010077.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:77054-78235:+ | gene-YDL204W_CBS6412 | rna-NM_001180264.1_CBS6412 | cds-NP_010077.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:94598-95779:+ | gene-YDL204W_CBS6413 | rna-NM_001180264.1_CBS6413 | cds-NP_010077.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:93272-94453:+ | gene-YDL204W_CENPK1137D | rna-NM_001180264.1_CENPK1137D | cds-NP_010077.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:90739-91920:+ | gene-YDL204W_EthanolRed | rna-NM_001180264.1_EthanolRed | cds-NP_010077.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:95345-96526:+ | gene-YDL204W_FaliES1 | rna-NM_001180264.1_FaliES1 | cds-NP_010077.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000344.1:22722-23903:- | gene-YDL204W_JAY291 | rna-NM_001180264.1_JAY291 | cds-NP_010077.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:92716-93897:+ | gene-YDL204W_MUCL30387 | rna-NM_001180264.1_MUCL30387 | cds-NP_010077.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:82285-83466:+ | gene-YDL204W_MUCL30388 | rna-NM_001180264.1_MUCL30388 | cds-NP_010077.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:77784-78965:+ | gene-YDL204W_MUCL39482 | rna-NM_001180264.1_MUCL39482 | cds-NP_010077.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:93860-95041:+ | gene-YDL204W_MUCL42920 | rna-NM_001180264.1_MUCL42920 | cds-NP_010077.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:94528-95709:+ | gene-YDL204W_NCIM3186 | rna-NM_001180264.1_NCIM3186 | cds-NP_010077.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:77741-78922:+ | gene-YDL204W_NCYC1407 | rna-NM_001180264.1_NCYC1407 | cds-NP_010077.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:85495-86676:+ | gene-YDL204W_PE2H3 | rna-NM_001180264.1_PE2H3 | cds-NP_010077.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:85505-86686:+ | gene-YDL204W_PE2H4 | rna-NM_001180264.1_PE2H4 | cds-NP_010077.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:94605-95786:+ | gene-YDL204W_S288C | rna-NM_001180264.1_S288C | cds-NP_010077.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000090.1:9098-10279:+ | gene-YDL204W_SA1 | rna-NM_001180264.1_SA1 | cds-NP_010077.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:95104-96285:+ | gene-YDL204W_ThermosaccDry | rna-NM_001180264.1_ThermosaccDry | cds-NP_010077.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:96045-97226:+ | gene-YDL204W_VR1 | rna-NM_001180264.1_VR1 | cds-NP_010077.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:93783-94964:+ | gene-YDL204W_ZTW1 | rna-NM_001180264.1_ZTW1 | cds-NP_010077.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:97158-98342:+ | gene-YDL204W_Sparadoxus | rna-NM_001180264.1_Sparadoxus | cds-NP_010077.1_Sparadoxus | 88.2 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |