Gene name: RTN1
Reference locus (S288C): YDR233C
Gene biotype: protein_coding
Description: Reticulon-like protein 1; Reticulon protein; involved in nuclear pore assembly and maintenance of tubular ER morphology; promotes membrane curvature; regulates the ER asymmetry-induced inheritance block during ER stress; role in ER-derived peroxisomal biogenesis; increases tubular ER when overexpressed; mutants have reduced phosphatidylserine transfer between the ER and mitochondria; interacts with exocyst subunit Sec6p, Yip3p, and Sbh1p; member of the RTNLA subfamily
Top 10 interactors (score): RTN2 (0.999); YOP1 (0.995); SEY1 (0.985); POM33 (0.967); LNP1 (0.932); PEX30 (0.922); SCS2 (0.91); SEC6 (0.836); PER33 (0.818); NDC1 (0.804); SEC63 (0.787); POM152 (0.785); PEP4 (0.784); SBH1 (0.764); POM34 (0.75); VPS54 (0.749); ICE2 (0.727); DPM1 (0.722); BRR6 (0.72); APQ12 (0.72)
Homologues (species, bitscore): RTN4 (Homo sapiens, 51.6); Rtn4 (Mus musculus, 51.2); rtn4a (Danio rerio, 52.0); Rtnl1 (Drosophila melanogaster, 50.1); AT5G58000 (Arabidopsis thaliana, 55.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:886156-887043:- | gene-YDR233C_AKU4011 | rna-NM_001180541.3_AKU4011 | cds-NP_010519.3_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:238767-239654:+ | gene-YDR233C_BG1 | rna-NM_001180541.3_BG1 | cds-NP_010519.3_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:918480-919367:- | gene-YDR233C_Bruggeman | rna-NM_001180541.3_Bruggeman | cds-NP_010519.3_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:905770-906657:- | gene-YDR233C_CAT1 | rna-NM_001180541.3_CAT1 | cds-NP_010519.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:876505-877392:- | gene-YDR233C_CBS1585 | rna-NM_001180541.3_CBS1585 | cds-NP_010519.3_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:905531-906418:- | gene-YDR233C_CBS436 | rna-NM_001180541.3_CBS436 | cds-NP_010519.3_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:873265-874152:- | gene-YDR233C_CBS6412 | rna-NM_001180541.3_CBS6412 | cds-NP_010519.3_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:903867-904754:- | gene-YDR233C_CBS6413 | rna-NM_001180541.3_CBS6413 | cds-NP_010519.3_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:928271-929158:- | gene-YDR233C_CENPK1137D | rna-NM_001180541.3_CENPK1137D | cds-NP_010519.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:886889-887776:- | gene-YDR233C_EthanolRed | rna-NM_001180541.3_EthanolRed | cds-NP_010519.3_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:895091-895978:- | gene-YDR233C_FaliES1 | rna-NM_001180541.3_FaliES1 | cds-NP_010519.3_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000348.1:15618-16505:+ | gene-YDR233C_JAY291 | rna-NM_001180541.3_JAY291 | cds-NP_010519.3_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:904378-905265:- | gene-YDR233C_MUCL30387 | rna-NM_001180541.3_MUCL30387 | cds-NP_010519.3_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:892408-893295:- | gene-YDR233C_MUCL30388 | rna-NM_001180541.3_MUCL30388 | cds-NP_010519.3_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:877910-878797:- | gene-YDR233C_MUCL39482 | rna-NM_001180541.3_MUCL39482 | cds-NP_010519.3_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:817185-818072:- | gene-YDR233C_MUCL42920 | rna-NM_001180541.3_MUCL42920 | cds-NP_010519.3_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:929393-930280:- | gene-YDR233C_NCIM3186 | rna-NM_001180541.3_NCIM3186 | cds-NP_010519.3_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:881578-882465:- | gene-YDR233C_NCYC1407 | rna-NM_001180541.3_NCYC1407 | cds-NP_010519.3_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:897833-898720:- | gene-YDR233C_PE2H3 | rna-NM_001180541.3_PE2H3 | cds-NP_010519.3_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:903110-903997:- | gene-YDR233C_PE2H4 | rna-NM_001180541.3_PE2H4 | cds-NP_010519.3_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:929470-930357:- | gene-YDR233C_S288C | rna-NM_001180541.3_S288C | cds-NP_010519.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000013.1:135664-136551:- | gene-YDR233C_SA1 | rna-NM_001180541.3_SA1 | cds-NP_010519.3_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:893245-894132:- | gene-YDR233C_ThermosaccDry | rna-NM_001180541.3_ThermosaccDry | cds-NP_010519.3_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:908433-909320:- | gene-YDR233C_VR1 | rna-NM_001180541.3_VR1 | cds-NP_010519.3_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000007.1:155920-156812:- | gene-YDR233C_ZTW1 | rna-NM_001180541.3_ZTW1 | cds-NP_010519.3_ZTW1 | 99.1 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:898075-898974:- | gene-YDR233C_Sparadoxus | rna-NM_001180541.3_Sparadoxus | cds-NP_010519.3_Sparadoxus | 90.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |