RTK1 (YDL025C)


Gene profile

Gene name: RTK1
Reference locus (S288C): YDL025C
Gene biotype: protein_coding

Description: Probable serine/threonine-protein kinase RTK1; Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress

Top 10 interactors (score): YGR016W (0.935); MEC1 (0.875); YDR239C (0.869); AIM2 (0.817); DPB11 (0.772); CAF120 (0.768); TDA3 (0.763); ACK1 (0.753); TEL1 (0.748); TOF1 (0.742); CSM3 (0.711); CDC45 (0.698); RAD24 (0.697); RAD51 (0.692); RAD17 (0.637); RPN6 (0.631); PKP2 (0.626); MIH1 (0.612); ARR2 (0.612); YCH1 (0.612)

Homologues (species, bitscore): CHEK1 (Homo sapiens, 122.1); Chek1 (Mus musculus, 117.5); mark4a (Danio rerio, 117.9); chek1 (Xenopus tropicalis, 122.5); KP78b (Drosophila melanogaster, 115.5); kin-33 (Caenorhabditis elegans, 117.1); CIPK25 (Arabidopsis thaliana, 117.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:391418-393280:- gene-YDL025C_AKU4011 rna-NM_001180084.1_AKU4011 cds-NP_010259.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000102.1:156586-158448:+ gene-YDL025C_BG1 rna-NM_001180084.1_BG1 cds-NP_010259.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:410085-411947:- gene-YDL025C_Bruggeman rna-NM_001180084.1_Bruggeman cds-NP_010259.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:404629-406491:- gene-YDL025C_CAT1 rna-NM_001180084.1_CAT1 cds-NP_010259.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:387834-389696:- gene-YDL025C_CBS1585 rna-NM_001180084.1_CBS1585 cds-NP_010259.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:405368-407230:- gene-YDL025C_CBS436 rna-NM_001180084.1_CBS436 cds-NP_010259.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:385630-387492:- gene-YDL025C_CBS6412 rna-NM_001180084.1_CBS6412 cds-NP_010259.1_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:407595-409457:- gene-YDL025C_CBS6413 rna-NM_001180084.1_CBS6413 cds-NP_010259.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:404204-406066:- gene-YDL025C_CENPK1137D rna-NM_001180084.1_CENPK1137D cds-NP_010259.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:400250-402112:- gene-YDL025C_EthanolRed rna-NM_001180084.1_EthanolRed cds-NP_010259.1_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:406442-408304:- gene-YDL025C_FaliES1 rna-NM_001180084.1_FaliES1 cds-NP_010259.1_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000370.1:20987-22849:- gene-YDL025C_JAY291 rna-NM_001180084.1_JAY291 cds-NP_010259.1_JAY291 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:405816-407678:- gene-YDL025C_MUCL30387 rna-NM_001180084.1_MUCL30387 cds-NP_010259.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:396330-398192:- gene-YDL025C_MUCL30388 rna-NM_001180084.1_MUCL30388 cds-NP_010259.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:389014-390876:- gene-YDL025C_MUCL39482 rna-NM_001180084.1_MUCL39482 cds-NP_010259.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:311376-313238:- gene-YDL025C_MUCL42920 rna-NM_001180084.1_MUCL42920 cds-NP_010259.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:405267-407129:- gene-YDL025C_NCIM3186 rna-NM_001180084.1_NCIM3186 cds-NP_010259.1_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:388927-390789:- gene-YDL025C_NCYC1407 rna-NM_001180084.1_NCYC1407 cds-NP_010259.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:396469-398331:- gene-YDL025C_PE2H3 rna-NM_001180084.1_PE2H3 cds-NP_010259.1_PE2H3 99.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:395827-397689:- gene-YDL025C_PE2H4 rna-NM_001180084.1_PE2H4 cds-NP_010259.1_PE2H4 99.3 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:405344-407206:- gene-YDL025C_S288C rna-NM_001180084.1_S288C cds-NP_010259.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000010.1:27730-29592:+ gene-YDL025C_SA1 rna-NM_001180084.1_SA1 cds-NP_010259.1_SA1 99.3 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:405902-407764:- gene-YDL025C_ThermosaccDry rna-NM_001180084.1_ThermosaccDry cds-NP_010259.1_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:408963-410825:- gene-YDL025C_VR1 rna-NM_001180084.1_VR1 cds-NP_010259.1_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:403802-405664:- gene-YDL025C_ZTW1 rna-NM_001180084.1_ZTW1 cds-NP_010259.1_ZTW1 99.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:408038-409909:- gene-YDL025C_Sparadoxus rna-NM_001180084.1_Sparadoxus cds-NP_010259.1_Sparadoxus 89.7 100.0 Verified 1 1 1 False True False False False

Additional files