Gene name: RTF1
Reference locus (S288C): YGL244W
Gene biotype: protein_coding
Description: RNA polymerase-associated protein RTF1; Subunit of RNAPII-associated chromatin remodeling Paf1 complex; regulates gene expression by directing cotranscriptional histone modification, influences transcription and chromatin structure through several independent functional domains; directly or indirectly regulates DNA-binding properties of Spt15p and relative activities of different TATA elements; involved in transcription elongation as demonstrated by the G-less-based run-on (GLRO) assay
Top 10 interactors (score): PAF1 (0.999); POB3 (0.999); SPT5 (0.999); CTR9 (0.999); CDC73 (0.999); LEO1 (0.999); SPT16 (0.998); RPO21 (0.997); CHD1 (0.996); SKI8 (0.995); SPT4 (0.993); SPT6 (0.989); DST1 (0.981); BRE1 (0.977); SET1 (0.97); RAD6 (0.958); SET2 (0.952); RPB3 (0.944); RPB2 (0.936); SPN1 (0.935)
Homologues (species, bitscore): RTF1 (Homo sapiens, 117.9); Rtf1 (Mus musculus, 117.9); rtf1 (Danio rerio, 115.5); rtf1 (Xenopus tropicalis, 103.2); Rtf1 (Drosophila melanogaster, 94.0); F25B3.6 (Caenorhabditis elegans, 52.0); VIP5 (Arabidopsis thaliana, 100.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:43023-44699:+ | gene-YGL244W_AKU4011 | rna-NM_001181110.1_AKU4011 | cds-NP_011270.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000175.1:35062-36738:+ | gene-YGL244W_BG1 | rna-NM_001181110.1_BG1 | cds-NP_011270.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:43378-45054:+ | gene-YGL244W_Bruggeman | rna-NM_001181110.1_Bruggeman | cds-NP_011270.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:41450-43126:+ | gene-YGL244W_CAT1 | rna-NM_001181110.1_CAT1 | cds-NP_011270.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:47311-48987:+ | gene-YGL244W_CBS1585 | rna-NM_001181110.1_CBS1585 | cds-NP_011270.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:42039-43715:+ | gene-YGL244W_CBS436 | rna-NM_001181110.1_CBS436 | cds-NP_011270.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:34879-36555:+ | gene-YGL244W_CBS6412 | rna-NM_001181110.1_CBS6412 | cds-NP_011270.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:41167-42843:+ | gene-YGL244W_CBS6413 | rna-NM_001181110.1_CBS6413 | cds-NP_011270.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:41160-42836:+ | gene-YGL244W_CENPK1137D | rna-NM_001181110.1_CENPK1137D | cds-NP_011270.1_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:34300-35976:+ | gene-YGL244W_EthanolRed | rna-NM_001181110.1_EthanolRed | cds-NP_011270.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:34661-36337:+ | gene-YGL244W_FaliES1 | rna-NM_001181110.1_FaliES1 | cds-NP_011270.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000079.1:30744-32420:- | gene-YGL244W_JAY291 | rna-NM_001181110.1_JAY291 | cds-NP_011270.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:43315-44991:+ | gene-YGL244W_MUCL30387 | rna-NM_001181110.1_MUCL30387 | cds-NP_011270.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:45468-47144:+ | gene-YGL244W_MUCL30388 | rna-NM_001181110.1_MUCL30388 | cds-NP_011270.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:43908-45584:+ | gene-YGL244W_MUCL39482 | rna-NM_001181110.1_MUCL39482 | cds-NP_011270.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:46801-48477:+ | gene-YGL244W_MUCL42920 | rna-NM_001181110.1_MUCL42920 | cds-NP_011270.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:41498-43174:+ | gene-YGL244W_NCIM3186 | rna-NM_001181110.1_NCIM3186 | cds-NP_011270.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:35672-37348:+ | gene-YGL244W_NCYC1407 | rna-NM_001181110.1_NCYC1407 | cds-NP_011270.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:37528-39204:+ | gene-YGL244W_PE2H3 | rna-NM_001181110.1_PE2H3 | cds-NP_011270.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:37076-38752:+ | gene-YGL244W_PE2H4 | rna-NM_001181110.1_PE2H4 | cds-NP_011270.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:41498-43174:+ | gene-YGL244W_S288C | rna-NM_001181110.1_S288C | cds-NP_011270.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:332160-333836:- | gene-YGL244W_SA1 | rna-NM_001181110.1_SA1 | cds-NP_011270.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:34976-36652:+ | gene-YGL244W_ThermosaccDry | rna-NM_001181110.1_ThermosaccDry | cds-NP_011270.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:41965-43641:+ | gene-YGL244W_VR1 | rna-NM_001181110.1_VR1 | cds-NP_011270.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:34049-35725:+ | gene-YGL244W_ZTW1 | rna-NM_001181110.1_ZTW1 | cds-NP_011270.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:42764-44437:+ | gene-YGL244W_Sparadoxus | rna-NM_001181110.1_Sparadoxus | cds-NP_011270.1_Sparadoxus | 91.9 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |