Gene name: RSC4
Reference locus (S288C): YKR008W
Gene biotype: protein_coding
Description: Chromatin structure-remodeling complex subunit RSC4; Component of the RSC chromatin remodeling complex; found in close proximity to nucleosomal DNA; displaced from the surface of nucleosomal DNA after chromatin remodeling; acetylated (K25) by Gcn5p, altering replication stress tolerance; contains tandem bromodomains that recognize histone H3 acetylated on K14 (H3K14ac) by Gcn5p
Top 10 interactors (score): RSC9 (0.999); RSC8 (0.999); RSC3 (0.999); ARP7 (0.999); RSC58 (0.999); ARP9 (0.999); NPL6 (0.999); STH1 (0.999); SFH1 (0.999); RSC2 (0.999); RSC6 (0.999); RSC1 (0.999); HTL1 (0.998); RTT102 (0.998); LDB7 (0.996); RSC30 (0.996); HHT2 (0.985); HHT1 (0.985); SNF5 (0.891); ISW1 (0.88)
Homologues (species, bitscore): PBRM1 (Homo sapiens, 74.7); Pbrm1 (Mus musculus, 75.1); pbrm1 (Danio rerio, 73.6); pbrm1 (Xenopus tropicalis, 74.3); polybromo (Drosophila melanogaster, 79.0); pbrm-1 (Caenorhabditis elegans, 74.3); HAG1 (Arabidopsis thaliana, 60.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:438199-440076:+ | gene-YKR008W_AKU4011 | rna-NM_001179798.4_AKU4011 | cds-NP_012933.4_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:203833-205710:- | gene-YKR008W_BG1 | rna-NM_001179798.4_BG1 | cds-NP_012933.4_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:459902-461779:+ | gene-YKR008W_Bruggeman | rna-NM_001179798.4_Bruggeman | cds-NP_012933.4_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:455007-456884:+ | gene-YKR008W_CAT1 | rna-NM_001179798.4_CAT1 | cds-NP_012933.4_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:450939-452816:+ | gene-YKR008W_CBS1585 | rna-NM_001179798.4_CBS1585 | cds-NP_012933.4_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:449776-451653:+ | gene-YKR008W_CBS436 | rna-NM_001179798.4_CBS436 | cds-NP_012933.4_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:435097-436974:+ | gene-YKR008W_CBS6412 | rna-NM_001179798.4_CBS6412 | cds-NP_012933.4_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:450771-452648:+ | gene-YKR008W_CBS6413 | rna-NM_001179798.4_CBS6413 | cds-NP_012933.4_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:451872-453749:+ | gene-YKR008W_CENPK1137D | rna-NM_001179798.4_CENPK1137D | cds-NP_012933.4_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:448680-450557:+ | gene-YKR008W_EthanolRed | rna-NM_001179798.4_EthanolRed | cds-NP_012933.4_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:450769-452646:+ | gene-YKR008W_FaliES1 | rna-NM_001179798.4_FaliES1 | cds-NP_012933.4_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000120.1:4161-6038:- | gene-YKR008W_JAY291 | rna-NM_001179798.4_JAY291 | cds-NP_012933.4_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:459216-461093:+ | gene-YKR008W_MUCL30387 | rna-NM_001179798.4_MUCL30387 | cds-NP_012933.4_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:454827-456704:+ | gene-YKR008W_MUCL30388 | rna-NM_001179798.4_MUCL30388 | cds-NP_012933.4_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:450256-452133:+ | gene-YKR008W_MUCL39482 | rna-NM_001179798.4_MUCL39482 | cds-NP_012933.4_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:456061-457938:+ | gene-YKR008W_MUCL42920 | rna-NM_001179798.4_MUCL42920 | cds-NP_012933.4_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:452190-454067:+ | gene-YKR008W_NCIM3186 | rna-NM_001179798.4_NCIM3186 | cds-NP_012933.4_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:450464-452341:+ | gene-YKR008W_NCYC1407 | rna-NM_001179798.4_NCYC1407 | cds-NP_012933.4_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:475114-476991:+ | gene-YKR008W_PE2H3 | rna-NM_001179798.4_PE2H3 | cds-NP_012933.4_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:459856-461733:+ | gene-YKR008W_PE2H4 | rna-NM_001179798.4_PE2H4 | cds-NP_012933.4_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:452201-454078:+ | gene-YKR008W_S288C | rna-NM_001179798.4_S288C | cds-NP_012933.4_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000027.1:130458-132335:+ | gene-YKR008W_SA1 | rna-NM_001179798.4_SA1 | cds-NP_012933.4_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:450867-452744:+ | gene-YKR008W_ThermosaccDry | rna-NM_001179798.4_ThermosaccDry | cds-NP_012933.4_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:450137-452014:+ | gene-YKR008W_VR1 | rna-NM_001179798.4_VR1 | cds-NP_012933.4_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:448905-450782:+ | gene-YKR008W_ZTW1 | rna-NM_001179798.4_ZTW1 | cds-NP_012933.4_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:473847-475724:+ | gene-YKR008W_Sparadoxus | rna-NM_001179798.4_Sparadoxus | cds-NP_012933.4_Sparadoxus | 91.3 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |