Gene name: RRS1
Reference locus (S288C): YOR294W
Gene biotype: protein_coding
Description: Regulator of ribosome biosynthesis; Essential protein that binds ribosomal protein L11; required for nuclear export of the 60S pre-ribosomal subunit during ribosome biogenesis; localizes to the nucleolus and in foci along nuclear periphery; cooperates with Ebp2p and Mps3p to mediate telomere clustering by binding Sir4p, but is not involved in telomere tethering; mouse homolog shows altered expression in Huntington's disease model mice; Belongs to the RRS1 family
Top 10 interactors (score): EBP2 (0.999); RPF2 (0.999); PUF6 (0.999); NOP15 (0.999); SPB1 (0.999); YTM1 (0.999); NOG1 (0.999); NOP4 (0.999); CIC1 (0.999); MRT4 (0.999); CGR1 (0.999); RLP7 (0.999); NIP7 (0.999); DBP10 (0.999); NOP7 (0.999); NMD3 (0.999); NUG1 (0.999); SSF1 (0.999); ERB1 (0.999); ARX1 (0.999)
Homologues (species, bitscore): RRS1 (Homo sapiens, 121.7); Rrs1 (Mus musculus, 124.4); rrs1 (Danio rerio, 115.9); CG32409 (Drosophila melanogaster, 101.7); rrbs-1 (Caenorhabditis elegans, 96.7); AT2G37990 (Arabidopsis thaliana, 83.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:858800-859411:+ | gene-YOR294W_AKU4011 | rna-NM_001183713.1_AKU4011 | cds-NP_014937.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:260844-261455:+ | gene-YOR294W_BG1 | rna-NM_001183713.1_BG1 | cds-NP_014937.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:844246-844857:+ | gene-YOR294W_Bruggeman | rna-NM_001183713.1_Bruggeman | cds-NP_014937.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:844971-845582:+ | gene-YOR294W_CAT1 | rna-NM_001183713.1_CAT1 | cds-NP_014937.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:842634-843245:+ | gene-YOR294W_CBS1585 | rna-NM_001183713.1_CBS1585 | cds-NP_014937.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:840475-841086:+ | gene-YOR294W_CBS436 | rna-NM_001183713.1_CBS436 | cds-NP_014937.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:838332-838943:+ | gene-YOR294W_CBS6412 | rna-NM_001183713.1_CBS6412 | cds-NP_014937.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:847527-848138:+ | gene-YOR294W_CBS6413 | rna-NM_001183713.1_CBS6413 | cds-NP_014937.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:868129-868740:+ | gene-YOR294W_CENPK1137D | rna-NM_001183713.1_CENPK1137D | cds-NP_014937.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:834713-835324:+ | gene-YOR294W_EthanolRed | rna-NM_001183713.1_EthanolRed | cds-NP_014937.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:840331-840942:+ | gene-YOR294W_FaliES1 | rna-NM_001183713.1_FaliES1 | cds-NP_014937.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000078.1:162299-162910:- | gene-YOR294W_JAY291 | rna-NM_001183713.1_JAY291 | cds-NP_014937.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:848497-849108:+ | gene-YOR294W_MUCL30387 | rna-NM_001183713.1_MUCL30387 | cds-NP_014937.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:856473-857084:+ | gene-YOR294W_MUCL30388 | rna-NM_001183713.1_MUCL30388 | cds-NP_014937.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:849162-849773:+ | gene-YOR294W_MUCL39482 | rna-NM_001183713.1_MUCL39482 | cds-NP_014937.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:858663-859274:+ | gene-YOR294W_MUCL42920 | rna-NM_001183713.1_MUCL42920 | cds-NP_014937.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:868229-868840:+ | gene-YOR294W_NCIM3186 | rna-NM_001183713.1_NCIM3186 | cds-NP_014937.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:850175-850786:+ | gene-YOR294W_NCYC1407 | rna-NM_001183713.1_NCYC1407 | cds-NP_014937.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:848407-849018:+ | gene-YOR294W_PE2H3 | rna-NM_001183713.1_PE2H3 | cds-NP_014937.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:864757-865368:+ | gene-YOR294W_PE2H4 | rna-NM_001183713.1_PE2H4 | cds-NP_014937.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:868340-868951:+ | gene-YOR294W_S288C | rna-NM_001183713.1_S288C | cds-NP_014937.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:278038-278649:+ | gene-YOR294W_SA1 | rna-NM_001183713.1_SA1 | cds-NP_014937.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:839514-840125:+ | gene-YOR294W_ThermosaccDry | rna-NM_001183713.1_ThermosaccDry | cds-NP_014937.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:902851-903462:+ | gene-YOR294W_VR1 | rna-NM_001183713.1_VR1 | cds-NP_014937.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:572402-573013:+ | gene-YOR294W_ZTW1 | rna-NM_001183713.1_ZTW1 | cds-NP_014937.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:846327-846938:+ | gene-YOR294W_Sparadoxus | rna-NM_001183713.1_Sparadoxus | cds-NP_014937.1_Sparadoxus | 91.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |