Gene name: RRP6
Reference locus (S288C): YOR001W
Gene biotype: protein_coding
Description: Nuclear exosome exonuclease component; has 3'-5' exonuclease activity that is regulated by Lrp1p; involved in RNA processing, maturation, surveillance, degradation, tethering, and export; role in sn/snoRNAs precursor degradation; forms a stable heterodimer with Lrp1p; has similarity to E. coli RNase D and to human PM-Sc1 100 (EXOSC10); mutant displays reduced transcription elongation in the G-less-based
Top 10 interactors (score): MPP6 (0.999); SKI7 (0.999); MTR3 (0.999); RRP46 (0.999); RRP43 (0.999); LRP1 (0.999); RRP40 (0.999); CSL4 (0.999); RRP42 (0.999); NOT5 (0.999); RRP4 (0.999); MOT2 (0.999); SKI6 (0.999); MTR4 (0.999); RRP45 (0.999); DIS3 (0.999); PWP2 (0.998); RAT1 (0.998); UTP13 (0.998); NOP14 (0.998)
Homologues (species, bitscore): EXOSC10 (Homo sapiens, 278.9); Exosc10 (Mus musculus, 278.5); exosc10 (Danio rerio, 291.2); exosc10 (Xenopus tropicalis, 257.7); Rrp6 (Drosophila melanogaster, 287.7); crn-3 (Caenorhabditis elegans, 259.2); AT5G35910 (Arabidopsis thaliana, 212.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:311190-313391:+ | gene-YOR001W_AKU4011 | rna-NM_001183420.1_AKU4011 | cds-NP_014643.1_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000152.1:126813-129014:+ | gene-YOR001W_BG1 | rna-NM_001183420.1_BG1 | cds-NP_014643.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:313965-316166:+ | gene-YOR001W_Bruggeman | rna-NM_001183420.1_Bruggeman | cds-NP_014643.1_Bruggeman | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:312119-314320:+ | gene-YOR001W_CAT1 | rna-NM_001183420.1_CAT1 | cds-NP_014643.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:305866-308067:+ | gene-YOR001W_CBS1585 | rna-NM_001183420.1_CBS1585 | cds-NP_014643.1_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:310145-312346:+ | gene-YOR001W_CBS436 | rna-NM_001183420.1_CBS436 | cds-NP_014643.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:305170-307371:+ | gene-YOR001W_CBS6412 | rna-NM_001183420.1_CBS6412 | cds-NP_014643.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:312703-314904:+ | gene-YOR001W_CBS6413 | rna-NM_001183420.1_CBS6413 | cds-NP_014643.1_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:326513-328714:+ | gene-YOR001W_CENPK1137D | rna-NM_001183420.1_CENPK1137D | cds-NP_014643.1_CENPK1137D | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:307953-310154:+ | gene-YOR001W_EthanolRed | rna-NM_001183420.1_EthanolRed | cds-NP_014643.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:311280-313481:+ | gene-YOR001W_FaliES1 | rna-NM_001183420.1_FaliES1 | cds-NP_014643.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000015.1:15748-17949:- | gene-YOR001W_JAY291 | rna-NM_001183420.1_JAY291 | cds-NP_014643.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:318180-320381:+ | gene-YOR001W_MUCL30387 | rna-NM_001183420.1_MUCL30387 | cds-NP_014643.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:321616-323817:+ | gene-YOR001W_MUCL30388 | rna-NM_001183420.1_MUCL30388 | cds-NP_014643.1_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:313349-315550:+ | gene-YOR001W_MUCL39482 | rna-NM_001183420.1_MUCL39482 | cds-NP_014643.1_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:328203-330404:+ | gene-YOR001W_MUCL42920 | rna-NM_001183420.1_MUCL42920 | cds-NP_014643.1_MUCL42920 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:326721-328922:+ | gene-YOR001W_NCIM3186 | rna-NM_001183420.1_NCIM3186 | cds-NP_014643.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:320034-322235:+ | gene-YOR001W_NCYC1407 | rna-NM_001183420.1_NCYC1407 | cds-NP_014643.1_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:314737-316938:+ | gene-YOR001W_PE2H3 | rna-NM_001183420.1_PE2H3 | cds-NP_014643.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:325116-327317:+ | gene-YOR001W_PE2H4 | rna-NM_001183420.1_PE2H4 | cds-NP_014643.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:326832-329033:+ | gene-YOR001W_S288C | rna-NM_001183420.1_S288C | cds-NP_014643.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:294804-297005:+ | gene-YOR001W_SA1 | rna-NM_001183420.1_SA1 | cds-NP_014643.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:309851-312052:+ | gene-YOR001W_ThermosaccDry | rna-NM_001183420.1_ThermosaccDry | cds-NP_014643.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:310688-312889:+ | gene-YOR001W_VR1 | rna-NM_001183420.1_VR1 | cds-NP_014643.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:44516-46717:+ | gene-YOR001W_ZTW1 | rna-NM_001183420.1_ZTW1 | cds-NP_014643.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:318331-320532:+ | gene-YOR001W_Sparadoxus | rna-NM_001183420.1_Sparadoxus | cds-NP_014643.1_Sparadoxus | 87.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |