Gene name: RRP45
Reference locus (S288C): YDR280W
Gene biotype: protein_coding
Description: Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp45p (PM/SCL-75, EXOSC9); protein abundance increases in response to DNA replication stress
Top 10 interactors (score): SKI7 (0.999); RRP46 (0.999); RRP40 (0.999); CSL4 (0.999); RRP43 (0.999); RRP6 (0.999); LRP1 (0.999); MPP6 (0.999); MTR3 (0.999); MTR4 (0.999); DIS3 (0.999); RRP42 (0.999); RRP4 (0.999); SKI6 (0.999); SKI2 (0.987); PNO1 (0.987); UTP6 (0.983); DIP2 (0.981); SKI3 (0.977); UTP22 (0.968)
Homologues (species, bitscore): EXOSC9 (Homo sapiens, 208.8); Exosc9 (Mus musculus, 207.2); exosc9 (Danio rerio, 213.0); exosc9 (Xenopus tropicalis, 224.2); Rrp45 (Drosophila melanogaster, 167.9); exos-9 (Caenorhabditis elegans, 185.7); CER7 (Arabidopsis thaliana, 216.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:973077-973994:+ | gene-YDR280W_AKU4011 | rna-NM_001180588.1_AKU4011 | cds-NP_010566.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:157906-158823:- | gene-YDR280W_BG1 | rna-NM_001180588.1_BG1 | cds-NP_010566.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:999225-1000142:+ | gene-YDR280W_Bruggeman | rna-NM_001180588.1_Bruggeman | cds-NP_010566.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:987363-988280:+ | gene-YDR280W_CAT1 | rna-NM_001180588.1_CAT1 | cds-NP_010566.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:967523-968440:+ | gene-YDR280W_CBS1585 | rna-NM_001180588.1_CBS1585 | cds-NP_010566.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:985545-986462:+ | gene-YDR280W_CBS436 | rna-NM_001180588.1_CBS436 | cds-NP_010566.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:964206-965123:+ | gene-YDR280W_CBS6412 | rna-NM_001180588.1_CBS6412 | cds-NP_010566.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:985442-986359:+ | gene-YDR280W_CBS6413 | rna-NM_001180588.1_CBS6413 | cds-NP_010566.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1019393-1020310:+ | gene-YDR280W_CENPK1137D | rna-NM_001180588.1_CENPK1137D | cds-NP_010566.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:971622-972539:+ | gene-YDR280W_EthanolRed | rna-NM_001180588.1_EthanolRed | cds-NP_010566.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:979824-980741:+ | gene-YDR280W_FaliES1 | rna-NM_001180588.1_FaliES1 | cds-NP_010566.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000297.1:1505-2422:- | gene-YDR280W_JAY291 | rna-NM_001180588.1_JAY291 | cds-NP_010566.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:985271-986188:+ | gene-YDR280W_MUCL30387 | rna-NM_001180588.1_MUCL30387 | cds-NP_010566.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:972588-973505:+ | gene-YDR280W_MUCL30388 | rna-NM_001180588.1_MUCL30388 | cds-NP_010566.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:959329-960246:+ | gene-YDR280W_MUCL39482 | rna-NM_001180588.1_MUCL39482 | cds-NP_010566.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:899314-900231:+ | gene-YDR280W_MUCL42920 | rna-NM_001180588.1_MUCL42920 | cds-NP_010566.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1020670-1021587:+ | gene-YDR280W_NCIM3186 | rna-NM_001180588.1_NCIM3186 | cds-NP_010566.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:972619-973536:+ | gene-YDR280W_NCYC1407 | rna-NM_001180588.1_NCYC1407 | cds-NP_010566.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:983275-984192:+ | gene-YDR280W_PE2H3 | rna-NM_001180588.1_PE2H3 | cds-NP_010566.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:988860-989777:+ | gene-YDR280W_PE2H4 | rna-NM_001180588.1_PE2H4 | cds-NP_010566.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1020747-1021664:+ | gene-YDR280W_S288C | rna-NM_001180588.1_S288C | cds-NP_010566.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000102.1:28403-29320:+ | gene-YDR280W_SA1 | rna-NM_001180588.1_SA1 | cds-NP_010566.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:984109-985026:+ | gene-YDR280W_ThermosaccDry | rna-NM_001180588.1_ThermosaccDry | cds-NP_010566.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:999702-1000619:+ | gene-YDR280W_VR1 | rna-NM_001180588.1_VR1 | cds-NP_010566.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:28232-29149:+ | gene-YDR280W_ZTW1 | rna-NM_001180588.1_ZTW1 | cds-NP_010566.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:979605-980522:+ | gene-YDR280W_Sparadoxus | rna-NM_001180588.1_Sparadoxus | cds-NP_010566.1_Sparadoxus | 91.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |