Gene name: RRM3
Reference locus (S288C): YHR031C
Gene biotype: protein_coding
Description: DNA helicase involved in rDNA replication and Ty1 transposition; binds to and suppresses DNA damage at G4 motifs in vivo; relieves replication fork pauses at telomeric regions; structurally and functionally related to Pif1p; Belongs to the helicase family
Top 10 interactors (score): SGS1 (0.998); SRS2 (0.993); TOF1 (0.986); RAD51 (0.983); RAD52 (0.982); MEC1 (0.968); MRC1 (0.962); DNA2 (0.958); RAD53 (0.958); CSM3 (0.953); POL2 (0.952); MUS81 (0.945); ORC5 (0.943); EST2 (0.937); TOP3 (0.932); FOB1 (0.929); MPH1 (0.927); POL30 (0.916); TEL1 (0.896); RAD27 (0.889)
Homologues (species, bitscore): PIF1 (Homo sapiens, 298.1); Pif1 (Mus musculus, 290.4); pif1 (Danio rerio, 303.1); pif1 (Xenopus tropicalis, 299.3); CG3238 (Drosophila melanogaster, 264.6); pif-1 (Caenorhabditis elegans, 297.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:159027-161198:- | gene-YHR031C_AKU4011 | rna-NM_001179161.1_AKU4011 | cds-NP_011896.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000053.1:79276-81447:- | gene-YHR031C_BG1 | rna-NM_001179161.1_BG1 | cds-NP_011896.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:166508-168679:- | gene-YHR031C_Bruggeman | rna-NM_001179161.1_Bruggeman | cds-NP_011896.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:160895-163066:- | gene-YHR031C_CAT1 | rna-NM_001179161.1_CAT1 | cds-NP_011896.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:159374-161545:- | gene-YHR031C_CBS1585 | rna-NM_001179161.1_CBS1585 | cds-NP_011896.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:153677-155848:- | gene-YHR031C_CBS436 | rna-NM_001179161.1_CBS436 | cds-NP_011896.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:158673-160844:- | gene-YHR031C_CBS6412 | rna-NM_001179161.1_CBS6412 | cds-NP_011896.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:159189-161360:- | gene-YHR031C_CBS6413 | rna-NM_001179161.1_CBS6413 | cds-NP_011896.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:164067-166238:- | gene-YHR031C_CENPK1137D | rna-NM_001179161.1_CENPK1137D | cds-NP_011896.1_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:158570-160741:- | gene-YHR031C_EthanolRed | rna-NM_001179161.1_EthanolRed | cds-NP_011896.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:159549-161720:- | gene-YHR031C_FaliES1 | rna-NM_001179161.1_FaliES1 | cds-NP_011896.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000273.1:19924-22095:+ | gene-YHR031C_JAY291 | rna-NM_001179161.1_JAY291 | cds-NP_011896.1_JAY291 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:165582-167753:- | gene-YHR031C_MUCL30387 | rna-NM_001179161.1_MUCL30387 | cds-NP_011896.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:166047-168218:- | gene-YHR031C_MUCL30388 | rna-NM_001179161.1_MUCL30388 | cds-NP_011896.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:158445-160616:- | gene-YHR031C_MUCL39482 | rna-NM_001179161.1_MUCL39482 | cds-NP_011896.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:165138-167309:- | gene-YHR031C_MUCL42920 | rna-NM_001179161.1_MUCL42920 | cds-NP_011896.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:170681-172852:- | gene-YHR031C_NCIM3186 | rna-NM_001179161.1_NCIM3186 | cds-NP_011896.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005270.1:158291-160462:- | gene-YHR031C_NCYC1407 | rna-NM_001179161.1_NCYC1407 | cds-NP_011896.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:160667-162838:- | gene-YHR031C_PE2H3 | rna-NM_001179161.1_PE2H3 | cds-NP_011896.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:168108-170279:- | gene-YHR031C_PE2H4 | rna-NM_001179161.1_PE2H4 | cds-NP_011896.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:170799-172970:- | gene-YHR031C_S288C | rna-NM_001179161.1_S288C | cds-NP_011896.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000106.1:24341-26512:- | gene-YHR031C_SA1 | rna-NM_001179161.1_SA1 | cds-NP_011896.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:160638-162809:- | gene-YHR031C_ThermosaccDry | rna-NM_001179161.1_ThermosaccDry | cds-NP_011896.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:167163-169334:- | gene-YHR031C_VR1 | rna-NM_001179161.1_VR1 | cds-NP_011896.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:152196-154367:- | gene-YHR031C_ZTW1 | rna-NM_001179161.1_ZTW1 | cds-NP_011896.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:158289-160460:- | gene-YHR031C_Sparadoxus | rna-NM_001179161.1_Sparadoxus | cds-NP_011896.1_Sparadoxus | 90.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |