RRD2 (YPL152W)


Gene profile

Gene name: RRD2
Reference locus (S288C): YPL152W
Gene biotype: protein_coding

Description: Serine/threonine-protein phosphatase 2A activator 2; Peptidyl-prolyl cis/trans-isomerase; also activates the phosphotyrosyl phosphatase activity of protein phosphatase 2A (PP2A); regulates G1 phase progression, the osmoresponse, microtubule dynamics; subunit of the Tap42p-Pph21p-Rrd2p complex; protein abundance increases in response to DNA replication stress

Top 10 interactors (score): PPH21 (0.999); TPD3 (0.999); SIT4 (0.997); PPH22 (0.993); PPH3 (0.99); CDC55 (0.99); TAP42 (0.986); PPE1 (0.975); PPM1 (0.967); GLC7 (0.964); RTS1 (0.949); PSY2 (0.947); CMP2 (0.944); CNA1 (0.942); PSY4 (0.936); RRD1 (0.929); SDS22 (0.926); CNB1 (0.917); GAC1 (0.915); TIP41 (0.912)

Homologues (species, bitscore): PPP2R4 (Homo sapiens, 212.2); Ppp2r4 (Mus musculus, 214.2); ppp2r4 (Danio rerio, 213.0); ptpa (Xenopus tropicalis, 125.9); Ptpa (Drosophila melanogaster, 172.9); Y71H2AM.20 (Caenorhabditis elegans, 203.4); AT4G08960 (Arabidopsis thaliana, 253.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:242683-243759:+ gene-YPL152W_AKU4011 rna-NM_001183966.1_AKU4011 cds-NP_015173.1_AKU4011 99.5 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000069.1:448371-449447:+ gene-YPL152W_BG1 rna-NM_001183966.1_BG1 cds-NP_015173.1_BG1 99.8 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:268676-269752:+ gene-YPL152W_Bruggeman rna-NM_001183966.1_Bruggeman cds-NP_015173.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:265360-266436:+ gene-YPL152W_CAT1 rna-NM_001183966.1_CAT1 cds-NP_015173.1_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:246746-247822:+ gene-YPL152W_CBS1585 rna-NM_001183966.1_CBS1585 cds-NP_015173.1_CBS1585 99.5 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:261423-262499:+ gene-YPL152W_CBS436 rna-NM_001183966.1_CBS436 cds-NP_015173.1_CBS436 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:251424-252500:+ gene-YPL152W_CBS6412 rna-NM_001183966.1_CBS6412 cds-NP_015173.1_CBS6412 99.5 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:243386-244462:+ gene-YPL152W_CBS6413 rna-NM_001183966.1_CBS6413 cds-NP_015173.1_CBS6413 99.5 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:264930-266006:+ gene-YPL152W_CENPK1137D rna-NM_001183966.1_CENPK1137D cds-NP_015173.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:241373-242449:+ gene-YPL152W_EthanolRed rna-NM_001183966.1_EthanolRed cds-NP_015173.1_EthanolRed 99.6 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:248965-250041:+ gene-YPL152W_FaliES1 rna-NM_001183966.1_FaliES1 cds-NP_015173.1_FaliES1 99.6 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000007.1:115809-116885:- gene-YPL152W_JAY291 rna-NM_001183966.1_JAY291 cds-NP_015173.1_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:259919-260995:+ gene-YPL152W_MUCL30387 rna-NM_001183966.1_MUCL30387 cds-NP_015173.1_MUCL30387 99.6 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:257936-259012:+ gene-YPL152W_MUCL30388 rna-NM_001183966.1_MUCL30388 cds-NP_015173.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:240075-241151:+ gene-YPL152W_MUCL39482 rna-NM_001183966.1_MUCL39482 cds-NP_015173.1_MUCL39482 99.5 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:297316-298392:+ gene-YPL152W_MUCL42920 rna-NM_001183966.1_MUCL42920 cds-NP_015173.1_MUCL42920 99.6 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:265011-266087:+ gene-YPL152W_NCIM3186 rna-NM_001183966.1_NCIM3186 cds-NP_015173.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:246538-247614:+ gene-YPL152W_NCYC1407 rna-NM_001183966.1_NCYC1407 cds-NP_015173.1_NCYC1407 99.5 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:253984-255060:+ gene-YPL152W_PE2H3 rna-NM_001183966.1_PE2H3 cds-NP_015173.1_PE2H3 99.5 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:253616-254692:+ gene-YPL152W_PE2H4 rna-NM_001183966.1_PE2H4 cds-NP_015173.1_PE2H4 99.8 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:265028-266104:+ gene-YPL152W_S288C rna-NM_001183966.1_S288C cds-NP_015173.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000012.1:107583-108659:- gene-YPL152W_SA1 rna-NM_001183966.1_SA1 cds-NP_015173.1_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:248763-249839:+ gene-YPL152W_ThermosaccDry rna-NM_001183966.1_ThermosaccDry cds-NP_015173.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:263744-264820:+ gene-YPL152W_VR1 rna-NM_001183966.1_VR1 cds-NP_015173.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:248091-249167:+ gene-YPL152W_ZTW1 rna-NM_001183966.1_ZTW1 cds-NP_015173.1_ZTW1 99.6 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:249732-250808:+ gene-YPL152W_Sparadoxus rna-NM_001183966.1_Sparadoxus cds-NP_015173.1_Sparadoxus 90.2 100.0 Verified 1 1 1 False True False False False

Additional files