Gene name: RRD1
Reference locus (S288C): YIL153W
Gene biotype: protein_coding
Description: Peptidyl-prolyl cis/trans-isomerase; activator of the phosphotyrosyl phosphatase activity of PP2A; involved in G1 phase progression, microtubule dynamics, bud morphogenesis and DNA repair; required for rapid reduction of Sgs1p levels in response to rapamycin; subunit of the Tap42p-Sit4p-Rrd1p complex; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; Belongs to the PTPA-type PPIase family
Top 10 interactors (score): SIT4 (0.999); TPD3 (0.997); PPH21 (0.993); TAP42 (0.992); PPH3 (0.991); PPH22 (0.982); PPE1 (0.975); PSY2 (0.968); CDC55 (0.951); ESS1 (0.937); RRD2 (0.929); TIP41 (0.925); RTS1 (0.911); PPM1 (0.903); PPG1 (0.877); SAP190 (0.875); PSY4 (0.867); SVF1 (0.861); YNL217W (0.855); QRI1 (0.846)
Homologues (species, bitscore): PPP2R4 (Homo sapiens, 211.5); Ppp2r4 (Mus musculus, 210.7); ppp2r4 (Danio rerio, 218.8); ptpa (Xenopus tropicalis, 151.4); Ptpa (Drosophila melanogaster, 204.5); Y71H2AM.20 (Caenorhabditis elegans, 179.9); AT4G08960 (Arabidopsis thaliana, 211.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:56415-57596:+ | gene-YIL153W_AKU4011 | rna-NM_001179501.1_AKU4011 | cds-NP_012113.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000174.1:79777-80958:- | gene-YIL153W_BG1 | rna-NM_001179501.1_BG1 | cds-NP_012113.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:59182-60363:+ | gene-YIL153W_Bruggeman | rna-NM_001179501.1_Bruggeman | cds-NP_012113.1_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:52988-54169:+ | gene-YIL153W_CAT1 | rna-NM_001179501.1_CAT1 | cds-NP_012113.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:56618-57799:+ | gene-YIL153W_CBS1585 | rna-NM_001179501.1_CBS1585 | cds-NP_012113.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:47769-48950:+ | gene-YIL153W_CBS436 | rna-NM_001179501.1_CBS436 | cds-NP_012113.1_CBS436 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:54147-55328:+ | gene-YIL153W_CBS6412 | rna-NM_001179501.1_CBS6412 | cds-NP_012113.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:48303-49484:+ | gene-YIL153W_CBS6413 | rna-NM_001179501.1_CBS6413 | cds-NP_012113.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:46901-48082:+ | gene-YIL153W_CENPK1137D | rna-NM_001179501.1_CENPK1137D | cds-NP_012113.1_CENPK1137D | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:41947-43128:+ | gene-YIL153W_EthanolRed | rna-NM_001179501.1_EthanolRed | cds-NP_012113.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:57751-58932:+ | gene-YIL153W_FaliES1 | rna-NM_001179501.1_FaliES1 | cds-NP_012113.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000319.1:49423-50604:- | gene-YIL153W_JAY291 | rna-NM_001179501.1_JAY291 | cds-NP_012113.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:56941-58122:+ | gene-YIL153W_MUCL30387 | rna-NM_001179501.1_MUCL30387 | cds-NP_012113.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:56182-57363:+ | gene-YIL153W_MUCL30388 | rna-NM_001179501.1_MUCL30388 | cds-NP_012113.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:57544-58725:+ | gene-YIL153W_MUCL39482 | rna-NM_001179501.1_MUCL39482 | cds-NP_012113.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:60764-61945:+ | gene-YIL153W_MUCL42920 | rna-NM_001179501.1_MUCL42920 | cds-NP_012113.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:55198-56379:+ | gene-YIL153W_NCIM3186 | rna-NM_001179501.1_NCIM3186 | cds-NP_012113.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:61510-62691:+ | gene-YIL153W_NCYC1407 | rna-NM_001179501.1_NCYC1407 | cds-NP_012113.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:56127-57308:+ | gene-YIL153W_PE2H3 | rna-NM_001179501.1_PE2H3 | cds-NP_012113.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:50089-51270:+ | gene-YIL153W_PE2H4 | rna-NM_001179501.1_PE2H4 | cds-NP_012113.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:55198-56379:+ | gene-YIL153W_S288C | rna-NM_001179501.1_S288C | cds-NP_012113.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000050.1:33780-34961:+ | gene-YIL153W_SA1 | rna-NM_001179501.1_SA1 | cds-NP_012113.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:56360-57541:+ | gene-YIL153W_ThermosaccDry | rna-NM_001179501.1_ThermosaccDry | cds-NP_012113.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:53552-54733:+ | gene-YIL153W_VR1 | rna-NM_001179501.1_VR1 | cds-NP_012113.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:31340-32521:+ | gene-YIL153W_ZTW1 | rna-NM_001179501.1_ZTW1 | cds-NP_012113.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:49082-50263:+ | gene-YIL153W_Sparadoxus | rna-NM_001179501.1_Sparadoxus | cds-NP_012113.1_Sparadoxus | 89.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |