Gene name: RQC1
Reference locus (S288C): YDR333C
Gene biotype: protein_coding
Description: Component of the ribosome quality control complex (RQC); RQC (Rqc1p-Rkr1p-Tae2p-Cdc48p-Npl4p-Ufd1p) is a ribosome-bound complex required for the degradation of polypeptides arising from stalled translation; required along with Rkr1p for recruitment of the Cdc48p-Npl4p-Ufd1p AAA ATPase complex to the RQC; Belongs to the TCF25 family
Top 10 interactors (score): RQC2 (0.999); RKR1 (0.999); CDC48 (0.998); UFD1 (0.99); NPL4 (0.99); VMS1 (0.95); HBS1 (0.923); DOM34 (0.868); HEL2 (0.818); VID27 (0.815); KRI1 (0.803); RLI1 (0.753); SKI7 (0.753); YPL225W (0.746); MOT2 (0.702); YPR097W (0.7); AIM29 (0.698); SDD2 (0.685); SFB3 (0.671); UBR1 (0.637)
Homologues (species, bitscore): TCF25 (Homo sapiens, 105.9); Tcf25 (Mus musculus, 111.7); tcf25 (Danio rerio, 101.3); tcf25 (Xenopus tropicalis, 71.6); CG7927 (Drosophila melanogaster, 107.8); K07A12.1 (Caenorhabditis elegans, 59.3); AT2G46900 (Arabidopsis thaliana, 65.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1079299-1081470:- | gene-YDR333C_AKU4011 | rna-NM_001180641.3_AKU4011 | cds-NP_010620.3_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:50089-52260:+ | gene-YDR333C_BG1 | rna-NM_001180641.3_BG1 | cds-NP_010620.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1106844-1109015:- | gene-YDR333C_Bruggeman | rna-NM_001180641.3_Bruggeman | cds-NP_010620.3_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1093590-1095761:- | gene-YDR333C_CAT1 | rna-NM_001180641.3_CAT1 | cds-NP_010620.3_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1073743-1075914:- | gene-YDR333C_CBS1585 | rna-NM_001180641.3_CBS1585 | cds-NP_010620.3_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1092127-1094298:- | gene-YDR333C_CBS436 | rna-NM_001180641.3_CBS436 | cds-NP_010620.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1070431-1072602:- | gene-YDR333C_CBS6412 | rna-NM_001180641.3_CBS6412 | cds-NP_010620.3_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1091662-1093833:- | gene-YDR333C_CBS6413 | rna-NM_001180641.3_CBS6413 | cds-NP_010620.3_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1131897-1134068:- | gene-YDR333C_CENPK1137D | rna-NM_001180641.3_CENPK1137D | cds-NP_010620.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:254839-257010:- | gene-YDR333C_EthanolRed | rna-NM_001180641.3_EthanolRed | cds-NP_010620.3_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1086054-1088225:- | gene-YDR333C_FaliES1 | rna-NM_001180641.3_FaliES1 | cds-NP_010620.3_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000386.1:38568-40739:- | gene-YDR333C_JAY291 | rna-NM_001180641.3_JAY291 | cds-NP_010620.3_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1092088-1094259:- | gene-YDR333C_MUCL30387 | rna-NM_001180641.3_MUCL30387 | cds-NP_010620.3_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1081043-1083214:- | gene-YDR333C_MUCL30388 | rna-NM_001180641.3_MUCL30388 | cds-NP_010620.3_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1065550-1067721:- | gene-YDR333C_MUCL39482 | rna-NM_001180641.3_MUCL39482 | cds-NP_010620.3_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1012621-1014792:- | gene-YDR333C_MUCL42920 | rna-NM_001180641.3_MUCL42920 | cds-NP_010620.3_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1133183-1135354:- | gene-YDR333C_NCIM3186 | rna-NM_001180641.3_NCIM3186 | cds-NP_010620.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1078841-1081012:- | gene-YDR333C_NCYC1407 | rna-NM_001180641.3_NCYC1407 | cds-NP_010620.3_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1089848-1092019:- | gene-YDR333C_PE2H3 | rna-NM_001180641.3_PE2H3 | cds-NP_010620.3_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1095433-1097604:- | gene-YDR333C_PE2H4 | rna-NM_001180641.3_PE2H4 | cds-NP_010620.3_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1133260-1135431:- | gene-YDR333C_S288C | rna-NM_001180641.3_S288C | cds-NP_010620.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000025.1:104070-106241:- | gene-YDR333C_SA1 | rna-NM_001180641.3_SA1 | cds-NP_010620.3_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1090327-1092498:- | gene-YDR333C_ThermosaccDry | rna-NM_001180641.3_ThermosaccDry | cds-NP_010620.3_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1106244-1108415:- | gene-YDR333C_VR1 | rna-NM_001180641.3_VR1 | cds-NP_010620.3_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:134437-136608:- | gene-YDR333C_ZTW1 | rna-NM_001180641.3_ZTW1 | cds-NP_010620.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1085723-1087900:- | gene-YDR333C_Sparadoxus | rna-NM_001180641.3_Sparadoxus | cds-NP_010620.3_Sparadoxus | 88.2 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |