Gene name: RPT6
Reference locus (S288C): YGL048C
Gene biotype: protein_coding
Description: ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; bound by ubiquitin-protein ligases Ubr1p and Ufd4p; localized mainly to the nucleus throughout the cell cycle; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): PRE2 (0.999); RPN2 (0.999); RPN6 (0.999); SEM1 (0.999); RPT1 (0.999); RPN3 (0.999); RPN13 (0.999); PRE8 (0.999); PRE10 (0.999); RPT4 (0.999); PRE4 (0.999); RPT3 (0.999); PRE7 (0.999); PUP3 (0.999); PRE1 (0.999); SCL1 (0.999); RPT2 (0.999); PRE5 (0.999); NAS6 (0.999); RPN1 (0.999)
Homologues (species, bitscore): PSMC5 (Homo sapiens, 629.4); Psmc5 (Mus musculus, 629.4); psmc5 (Danio rerio, 630.6); psmc5 (Xenopus tropicalis, 625.2); Rpt6 (Drosophila melanogaster, 625.5); rpt-6 (Caenorhabditis elegans, 625.2); RPT6A (Arabidopsis thaliana, 611.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:412144-413361:- | gene-YGL048C_AKU4011 | rna-NM_001180913.1_AKU4011 | cds-NP_011467.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000060.1:162768-163985:+ | gene-YGL048C_BG1 | rna-NM_001180913.1_BG1 | cds-NP_011467.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:412713-413930:- | gene-YGL048C_Bruggeman | rna-NM_001180913.1_Bruggeman | cds-NP_011467.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:411126-412343:- | gene-YGL048C_CAT1 | rna-NM_001180913.1_CAT1 | cds-NP_011467.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:413607-414824:- | gene-YGL048C_CBS1585 | rna-NM_001180913.1_CBS1585 | cds-NP_011467.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:407733-408950:- | gene-YGL048C_CBS436 | rna-NM_001180913.1_CBS436 | cds-NP_011467.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:405787-407004:- | gene-YGL048C_CBS6412 | rna-NM_001180913.1_CBS6412 | cds-NP_011467.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:409824-411041:- | gene-YGL048C_CBS6413 | rna-NM_001180913.1_CBS6413 | cds-NP_011467.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:409911-411128:- | gene-YGL048C_CENPK1137D | rna-NM_001180913.1_CENPK1137D | cds-NP_011467.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:400520-401737:- | gene-YGL048C_EthanolRed | rna-NM_001180913.1_EthanolRed | cds-NP_011467.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:403783-405000:- | gene-YGL048C_FaliES1 | rna-NM_001180913.1_FaliES1 | cds-NP_011467.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000165.1:11831-13048:+ | gene-YGL048C_JAY291 | rna-NM_001180913.1_JAY291 | cds-NP_011467.1_JAY291 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:409917-411134:- | gene-YGL048C_MUCL30387 | rna-NM_001180913.1_MUCL30387 | cds-NP_011467.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:412964-414181:- | gene-YGL048C_MUCL30388 | rna-NM_001180913.1_MUCL30388 | cds-NP_011467.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:409400-410617:- | gene-YGL048C_MUCL39482 | rna-NM_001180913.1_MUCL39482 | cds-NP_011467.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:417818-419035:- | gene-YGL048C_MUCL42920 | rna-NM_001180913.1_MUCL42920 | cds-NP_011467.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:410069-411286:- | gene-YGL048C_NCIM3186 | rna-NM_001180913.1_NCIM3186 | cds-NP_011467.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:403525-404742:- | gene-YGL048C_NCYC1407 | rna-NM_001180913.1_NCYC1407 | cds-NP_011467.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:406098-407315:- | gene-YGL048C_PE2H3 | rna-NM_001180913.1_PE2H3 | cds-NP_011467.1_PE2H3 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:411148-412365:- | gene-YGL048C_PE2H4 | rna-NM_001180913.1_PE2H4 | cds-NP_011467.1_PE2H4 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:410069-411286:- | gene-YGL048C_S288C | rna-NM_001180913.1_S288C | cds-NP_011467.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000021.1:144342-145559:+ | gene-YGL048C_SA1 | rna-NM_001180913.1_SA1 | cds-NP_011467.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:423147-424364:- | gene-YGL048C_ThermosaccDry | rna-NM_001180913.1_ThermosaccDry | cds-NP_011467.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:513093-514310:- | gene-YGL048C_VR1 | rna-NM_001180913.1_VR1 | cds-NP_011467.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:401387-402604:- | gene-YGL048C_ZTW1 | rna-NM_001180913.1_ZTW1 | cds-NP_011467.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:410815-412032:- | gene-YGL048C_Sparadoxus | rna-NM_001180913.1_Sparadoxus | cds-NP_011467.1_Sparadoxus | 92.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |