RPT4 (YOR259C)


Gene profile

Gene name: RPT4
Reference locus (S288C): YOR259C
Gene biotype: protein_coding

Description: 26S proteasome subunit RPT4; ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in degradation of ubiquitinated substrates; contributes preferentially to ERAD; required for spindle pole body duplication; mainly nuclear localization

Top 10 interactors (score): PRE3 (0.999); RPT3 (0.999); PRE4 (0.999); PRE1 (0.999); PUP3 (0.999); PRE7 (0.999); PRE8 (0.999); RPN13 (0.999); RPN3 (0.999); RPT6 (0.999); PRE10 (0.999); RPT1 (0.999); RPN2 (0.999); SEM1 (0.999); RPN6 (0.999); RPN1 (0.999); NAS6 (0.999); PRE5 (0.999); RPT2 (0.999); SCL1 (0.999)

Homologues (species, bitscore): PSMC6 (Homo sapiens, 557.4); Psmc6 (Mus musculus, 558.1); psmc6 (Danio rerio, 557.8); psmc6 (Xenopus tropicalis, 553.9); Rpt4 (Drosophila melanogaster, 576.2); rpt-4 (Caenorhabditis elegans, 545.0); RPT4A (Arabidopsis thaliana, 546.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:803170-804483:- gene-YOR259C_AKU4011 rna-NM_001183678.3_AKU4011 cds-NP_014902.3_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000123.1:205203-206516:- gene-YOR259C_BG1 rna-NM_001183678.3_BG1 cds-NP_014902.3_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:788629-789942:- gene-YOR259C_Bruggeman rna-NM_001183678.3_Bruggeman cds-NP_014902.3_Bruggeman 99.7 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:789281-790594:- gene-YOR259C_CAT1 rna-NM_001183678.3_CAT1 cds-NP_014902.3_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:786159-787472:- gene-YOR259C_CBS1585 rna-NM_001183678.3_CBS1585 cds-NP_014902.3_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:784847-786160:- gene-YOR259C_CBS436 rna-NM_001183678.3_CBS436 cds-NP_014902.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:783278-784591:- gene-YOR259C_CBS6412 rna-NM_001183678.3_CBS6412 cds-NP_014902.3_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:791919-793232:- gene-YOR259C_CBS6413 rna-NM_001183678.3_CBS6413 cds-NP_014902.3_CBS6413 99.7 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:812156-813469:- gene-YOR259C_CENPK1137D rna-NM_001183678.3_CENPK1137D cds-NP_014902.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:779286-780599:- gene-YOR259C_EthanolRed rna-NM_001183678.3_EthanolRed cds-NP_014902.3_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:784685-785998:- gene-YOR259C_FaliES1 rna-NM_001183678.3_FaliES1 cds-NP_014902.3_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000381.1:40836-42149:+ gene-YOR259C_JAY291 rna-NM_001183678.3_JAY291 cds-NP_014902.3_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:792911-794224:- gene-YOR259C_MUCL30387 rna-NM_001183678.3_MUCL30387 cds-NP_014902.3_MUCL30387 99.6 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:800027-801340:- gene-YOR259C_MUCL30388 rna-NM_001183678.3_MUCL30388 cds-NP_014902.3_MUCL30388 99.7 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:793490-794803:- gene-YOR259C_MUCL39482 rna-NM_001183678.3_MUCL39482 cds-NP_014902.3_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:803074-804387:- gene-YOR259C_MUCL42920 rna-NM_001183678.3_MUCL42920 cds-NP_014902.3_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:812284-813597:- gene-YOR259C_NCIM3186 rna-NM_001183678.3_NCIM3186 cds-NP_014902.3_NCIM3186 99.6 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:793588-794901:- gene-YOR259C_NCYC1407 rna-NM_001183678.3_NCYC1407 cds-NP_014902.3_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:792885-794198:- gene-YOR259C_PE2H3 rna-NM_001183678.3_PE2H3 cds-NP_014902.3_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:803262-804575:- gene-YOR259C_PE2H4 rna-NM_001183678.3_PE2H4 cds-NP_014902.3_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:812395-813708:- gene-YOR259C_S288C rna-NM_001183678.3_S288C cds-NP_014902.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000006.1:222385-223698:- gene-YOR259C_SA1 rna-NM_001183678.3_SA1 cds-NP_014902.3_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:783868-785181:- gene-YOR259C_ThermosaccDry rna-NM_001183678.3_ThermosaccDry cds-NP_014902.3_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:847325-848638:- gene-YOR259C_VR1 rna-NM_001183678.3_VR1 cds-NP_014902.3_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:516787-518100:- gene-YOR259C_ZTW1 rna-NM_001183678.3_ZTW1 cds-NP_014902.3_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:789653-790966:- gene-YOR259C_Sparadoxus rna-NM_001183678.3_Sparadoxus cds-NP_014902.3_Sparadoxus 92.5 100.0 Verified 1 1 1 False True False False False

Additional files