RPT2 (YDL007W)


Gene profile

Gene name: RPT2
Reference locus (S288C): YDL007W
Gene biotype: protein_coding

Description: ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; required for normal peptide hydrolysis by the core 20S particle; N-myristoylation of Rpt2p at Gly2 is involved in regulating the proper intracellular distribution of proteasome activity by controlling the nuclear localization of the 26S proteasome

Top 10 interactors (score): PUP2 (0.999); SCL1 (0.999); RPN1 (0.999); NAS6 (0.999); PRE5 (0.999); RPN2 (0.999); SEM1 (0.999); RPN6 (0.999); RPT1 (0.999); PRE8 (0.999); RPN13 (0.999); RPN3 (0.999); RPT6 (0.999); PRE10 (0.999); PRE4 (0.999); RPT3 (0.999); RPT4 (0.999); PRE1 (0.999); PUP3 (0.999); PRE7 (0.999)

Homologues (species, bitscore): PSMC1 (Homo sapiens, 643.7); Psmc1 (Mus musculus, 643.7); psmc1a (Danio rerio, 646.0); psmc1 (Xenopus tropicalis, 641.3); Rpt2 (Drosophila melanogaster, 642.1); rpt-2 (Caenorhabditis elegans, 624.4); RPT2b (Arabidopsis thaliana, 631.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:423303-424616:+ gene-YDL007W_AKU4011 rna-NM_001180066.1_AKU4011 cds-NP_010277.1_AKU4011 99.9 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000102.1:124794-126107:- gene-YDL007W_BG1 rna-NM_001180066.1_BG1 cds-NP_010277.1_BG1 99.6 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:443902-445215:+ gene-YDL007W_Bruggeman rna-NM_001180066.1_Bruggeman cds-NP_010277.1_Bruggeman 99.9 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:436749-438062:+ gene-YDL007W_CAT1 rna-NM_001180066.1_CAT1 cds-NP_010277.1_CAT1 99.6 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:420514-421827:+ gene-YDL007W_CBS1585 rna-NM_001180066.1_CBS1585 cds-NP_010277.1_CBS1585 99.9 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:437277-438590:+ gene-YDL007W_CBS436 rna-NM_001180066.1_CBS436 cds-NP_010277.1_CBS436 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:417762-419075:+ gene-YDL007W_CBS6412 rna-NM_001180066.1_CBS6412 cds-NP_010277.1_CBS6412 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:439452-440765:+ gene-YDL007W_CBS6413 rna-NM_001180066.1_CBS6413 cds-NP_010277.1_CBS6413 99.9 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:436910-438223:+ gene-YDL007W_CENPK1137D rna-NM_001180066.1_CENPK1137D cds-NP_010277.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:432136-433449:+ gene-YDL007W_EthanolRed rna-NM_001180066.1_EthanolRed cds-NP_010277.1_EthanolRed 99.9 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:438304-439617:+ gene-YDL007W_FaliES1 rna-NM_001180066.1_FaliES1 cds-NP_010277.1_FaliES1 99.9 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000442.1:32423-33736:- gene-YDL007W_JAY291 rna-NM_001180066.1_JAY291 cds-NP_010277.1_JAY291 99.6 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:437773-439086:+ gene-YDL007W_MUCL30387 rna-NM_001180066.1_MUCL30387 cds-NP_010277.1_MUCL30387 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:428235-429548:+ gene-YDL007W_MUCL30388 rna-NM_001180066.1_MUCL30388 cds-NP_010277.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:421883-423196:+ gene-YDL007W_MUCL39482 rna-NM_001180066.1_MUCL39482 cds-NP_010277.1_MUCL39482 99.9 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:343308-344621:+ gene-YDL007W_MUCL42920 rna-NM_001180066.1_MUCL42920 cds-NP_010277.1_MUCL42920 99.9 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:437970-439283:+ gene-YDL007W_NCIM3186 rna-NM_001180066.1_NCIM3186 cds-NP_010277.1_NCIM3186 99.8 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:420805-422118:+ gene-YDL007W_NCYC1407 rna-NM_001180066.1_NCYC1407 cds-NP_010277.1_NCYC1407 99.9 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:436381-437694:+ gene-YDL007W_PE2H3 rna-NM_001180066.1_PE2H3 cds-NP_010277.1_PE2H3 99.6 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:435740-437053:+ gene-YDL007W_PE2H4 rna-NM_001180066.1_PE2H4 cds-NP_010277.1_PE2H4 99.6 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:438047-439360:+ gene-YDL007W_S288C rna-NM_001180066.1_S288C cds-NP_010277.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000099.1:32612-33925:- gene-YDL007W_SA1 rna-NM_001180066.1_SA1 cds-NP_010277.1_SA1 99.6 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:437784-439097:+ gene-YDL007W_ThermosaccDry rna-NM_001180066.1_ThermosaccDry cds-NP_010277.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:442238-443551:+ gene-YDL007W_VR1 rna-NM_001180066.1_VR1 cds-NP_010277.1_VR1 99.6 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:435678-436991:+ gene-YDL007W_ZTW1 rna-NM_001180066.1_ZTW1 cds-NP_010277.1_ZTW1 99.9 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:440062-441375:+ gene-YDL007W_Sparadoxus rna-NM_001180066.1_Sparadoxus cds-NP_010277.1_Sparadoxus 94.2 100.0 Verified 1 1 1 True True False False False

Additional files