RPT1 (YKL145W)


Gene profile

Gene name: RPT1
Reference locus (S288C): YKL145W
Gene biotype: protein_coding

Description: ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; required for optimal CDC20 transcription; interacts with Rpn12p and Ubr1p; mutant has aneuploidy tolerance

Top 10 interactors (score): RPN1 (0.999); PRE5 (0.999); NAS6 (0.999); RPT2 (0.999); HSM3 (0.999); SCL1 (0.999); RPN3 (0.999); PRE8 (0.999); RPN13 (0.999); SEM1 (0.999); RPN6 (0.999); RPN2 (0.999); PUP3 (0.999); PRE1 (0.999); PRE7 (0.999); PRE4 (0.999); RPT3 (0.999); RPT4 (0.999); RPT6 (0.999); PRE10 (0.999)

Homologues (species, bitscore): PSMC2 (Homo sapiens, 670.6); Psmc2 (Mus musculus, 671.0); psmc2 (Danio rerio, 669.5); psmc2 (Xenopus tropicalis, 668.3); Rpt1 (Drosophila melanogaster, 651.4); rpt-1 (Caenorhabditis elegans, 659.1); RPT1A (Arabidopsis thaliana, 654.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:161091-162494:+ gene-YKL145W_AKU4011 rna-NM_001179711.1_AKU4011 cds-NP_012777.1_AKU4011 99.6 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000030.1:138223-139626:+ gene-YKL145W_BG1 rna-NM_001179711.1_BG1 cds-NP_012777.1_BG1 99.8 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:178752-180155:+ gene-YKL145W_Bruggeman rna-NM_001179711.1_Bruggeman cds-NP_012777.1_Bruggeman 99.6 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:174077-175480:+ gene-YKL145W_CAT1 rna-NM_001179711.1_CAT1 cds-NP_012777.1_CAT1 99.5 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:173322-174725:+ gene-YKL145W_CBS1585 rna-NM_001179711.1_CBS1585 cds-NP_012777.1_CBS1585 99.6 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:171922-173325:+ gene-YKL145W_CBS436 rna-NM_001179711.1_CBS436 cds-NP_012777.1_CBS436 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:158336-159739:+ gene-YKL145W_CBS6412 rna-NM_001179711.1_CBS6412 cds-NP_012777.1_CBS6412 99.6 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:173786-175189:+ gene-YKL145W_CBS6413 rna-NM_001179711.1_CBS6413 cds-NP_012777.1_CBS6413 99.6 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:173857-175260:+ gene-YKL145W_CENPK1137D rna-NM_001179711.1_CENPK1137D cds-NP_012777.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:171825-173228:+ gene-YKL145W_EthanolRed rna-NM_001179711.1_EthanolRed cds-NP_012777.1_EthanolRed 99.6 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:172637-174040:+ gene-YKL145W_FaliES1 rna-NM_001179711.1_FaliES1 cds-NP_012777.1_FaliES1 99.6 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000198.1:9350-10753:+ gene-YKL145W_JAY291 rna-NM_001179711.1_JAY291 cds-NP_012777.1_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:180849-182252:+ gene-YKL145W_MUCL30387 rna-NM_001179711.1_MUCL30387 cds-NP_012777.1_MUCL30387 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:175201-176604:+ gene-YKL145W_MUCL30388 rna-NM_001179711.1_MUCL30388 cds-NP_012777.1_MUCL30388 99.7 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:173123-174526:+ gene-YKL145W_MUCL39482 rna-NM_001179711.1_MUCL39482 cds-NP_012777.1_MUCL39482 99.6 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:177512-178915:+ gene-YKL145W_MUCL42920 rna-NM_001179711.1_MUCL42920 cds-NP_012777.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:174202-175605:+ gene-YKL145W_NCIM3186 rna-NM_001179711.1_NCIM3186 cds-NP_012777.1_NCIM3186 99.6 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:173313-174716:+ gene-YKL145W_NCYC1407 rna-NM_001179711.1_NCYC1407 cds-NP_012777.1_NCYC1407 99.6 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:180410-181813:+ gene-YKL145W_PE2H3 rna-NM_001179711.1_PE2H3 cds-NP_012777.1_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:176704-178107:+ gene-YKL145W_PE2H4 rna-NM_001179711.1_PE2H4 cds-NP_012777.1_PE2H4 99.9 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:174213-175616:+ gene-YKL145W_S288C rna-NM_001179711.1_S288C cds-NP_012777.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000008.1:90635-92038:+ gene-YKL145W_SA1 rna-NM_001179711.1_SA1 cds-NP_012777.1_SA1 99.5 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:173337-174740:+ gene-YKL145W_ThermosaccDry rna-NM_001179711.1_ThermosaccDry cds-NP_012777.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:172688-174091:+ gene-YKL145W_VR1 rna-NM_001179711.1_VR1 cds-NP_012777.1_VR1 99.8 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:171870-173273:+ gene-YKL145W_ZTW1 rna-NM_001179711.1_ZTW1 cds-NP_012777.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:188568-189971:+ gene-YKL145W_Sparadoxus rna-NM_001179711.1_Sparadoxus cds-NP_012777.1_Sparadoxus 92.2 100.0 Verified 1 1 1 False True False False False

Additional files