RPO41 (YFL036W)


Gene profile

Gene name: RPO41
Reference locus (S288C): YFL036W
Gene biotype: protein_coding

Description: Mitochondrial RNA polymerase; single subunit enzyme similar to those of T3 and T7 bacteriophages; requires a specificity subunit encoded by MTF1 for promoter recognition; Mtf1p interacts with and stabilizes the Rpo41p-promoter complex, enhancing DNA bending and melting to facilitate pre-initiation open complex formation; Rpo41p also synthesizes RNA primers for mitochondrial DNA replication

Top 10 interactors (score): MTF1 (0.999); MTF2 (0.971); MNP1 (0.957); PET309 (0.954); SUV3 (0.951); DIM1 (0.936); MIP1 (0.922); ATP6 (0.914); RET1 (0.89); MGM101 (0.883); MSS116 (0.882); ABF2 (0.881); NOG2 (0.876); PWP2 (0.872); COB (0.866); COX2 (0.849); ORI5 (0.846); COX1 (0.831); CCM1 (0.789); IRC3 (0.759)

Homologues (species, bitscore): POLRMT (Homo sapiens, 488.0); Polrmt (Mus musculus, 475.7); POLRMT (Danio rerio, 494.2); polrmt (Xenopus tropicalis, 487.6); mtRNApol (Drosophila melanogaster, 447.2); rpom-1 (Caenorhabditis elegans, 382.9); AT5G15700 (Arabidopsis thaliana, 539.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005300.1:55112-59167:+ gene-YFL036W_AKU4011 rna-NM_001179930.1_AKU4011 cds-NP_116617.1_AKU4011 99.9 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000182.1:10565-14620:- gene-YFL036W_BG1 rna-NM_001179930.1_BG1 cds-NP_116617.1_BG1 99.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005508.1:53984-58039:+ gene-YFL036W_Bruggeman rna-NM_001179930.1_Bruggeman cds-NP_116617.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005524.1:58878-62933:+ gene-YFL036W_CAT1 rna-NM_001179930.1_CAT1 cds-NP_116617.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005364.1:55921-59976:+ gene-YFL036W_CBS1585 rna-NM_001179930.1_CBS1585 cds-NP_116617.1_CBS1585 99.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005348.1:29421-33476:+ gene-YFL036W_CBS436 rna-NM_001179930.1_CBS436 cds-NP_116617.1_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005332.1:55657-59712:+ gene-YFL036W_CBS6412 rna-NM_001179930.1_CBS6412 cds-NP_116617.1_CBS6412 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005316.1:58187-62242:+ gene-YFL036W_CBS6413 rna-NM_001179930.1_CBS6413 cds-NP_116617.1_CBS6413 99.9 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001527.1:55112-59167:+ gene-YFL036W_CENPK1137D rna-NM_001179930.1_CENPK1137D cds-NP_116617.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005476.1:54239-58294:+ gene-YFL036W_EthanolRed rna-NM_001179930.1_EthanolRed cds-NP_116617.1_EthanolRed 99.9 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005540.1:55663-59718:+ gene-YFL036W_FaliES1 rna-NM_001179930.1_FaliES1 cds-NP_116617.1_FaliES1 99.9 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000448.1:64113-68168:+ gene-YFL036W_JAY291 rna-NM_001179930.1_JAY291 cds-NP_116617.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005412.1:56084-60139:+ gene-YFL036W_MUCL30387 rna-NM_001179930.1_MUCL30387 cds-NP_116617.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005444.1:53983-58038:+ gene-YFL036W_MUCL30388 rna-NM_001179930.1_MUCL30388 cds-NP_116617.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005284.1:54306-58361:+ gene-YFL036W_MUCL39482 rna-NM_001179930.1_MUCL39482 cds-NP_116617.1_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005428.1:52005-56060:+ gene-YFL036W_MUCL42920 rna-NM_001179930.1_MUCL42920 cds-NP_116617.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011815.1:58781-62836:+ gene-YFL036W_NCIM3186 rna-NM_001179930.1_NCIM3186 cds-NP_116617.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005268.1:55379-59434:+ gene-YFL036W_NCYC1407 rna-NM_001179930.1_NCYC1407 cds-NP_116617.1_NCYC1407 99.9 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994145.1:75268-79323:+ gene-YFL036W_PE2H3 rna-NM_001179930.1_PE2H3 cds-NP_116617.1_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999877.1:74819-78874:+ gene-YFL036W_PE2H4 rna-NM_001179930.1_PE2H4 cds-NP_116617.1_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001138.5:58782-62837:+ gene-YFL036W_S288C rna-NM_001179930.1_S288C cds-NP_116617.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000004.1:272798-276853:- gene-YFL036W_SA1 rna-NM_001179930.1_SA1 cds-NP_116617.1_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005492.1:54856-58911:+ gene-YFL036W_ThermosaccDry rna-NM_001179930.1_ThermosaccDry cds-NP_116617.1_ThermosaccDry 99.9 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005460.1:63394-67449:+ gene-YFL036W_VR1 rna-NM_001179930.1_VR1 cds-NP_116617.1_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000012.1:40146-44201:+ gene-YFL036W_ZTW1 rna-NM_001179930.1_ZTW1 cds-NP_116617.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047492.1:79183-83238:+ gene-YFL036W_Sparadoxus rna-NM_001179930.1_Sparadoxus cds-NP_116617.1_Sparadoxus 90.4 100.0 Verified 1 1 1 False True False False False

Additional files