RPN8 (YOR261C)


Gene profile

Gene name: RPN8
Reference locus (S288C): YOR261C
Gene biotype: protein_coding

Description: Essential non-ATPase regulatory subunit of the 26S proteasome; has similarity to the human p40 proteasomal subunit and to another S. cerevisiae regulatory subunit, Rpn11p; Belongs to the peptidase M67A family

Top 10 interactors (score): RPN5 (0.999); RPN12 (0.999); PRE3 (0.999); RPN7 (0.999); PUP1 (0.999); RPT5 (0.999); RPN9 (0.999); UBP6 (0.999); PRE2 (0.999); RPN10 (0.999); RPN11 (0.999); RPN2 (0.999); RPT1 (0.999); RPT2 (0.999); PRE5 (0.999); RPN1 (0.999); SCL1 (0.999); PRE6 (0.999); PUP2 (0.999); PRE9 (0.999)

Homologues (species, bitscore): PSMD7 (Homo sapiens, 320.9); Psmd7 (Mus musculus, 317.4); psmd7 (Danio rerio, 319.3); psmd7 (Xenopus tropicalis, 315.8); Rpn8 (Drosophila melanogaster, 310.1); rpn-8 (Caenorhabditis elegans, 292.0); MEE34 (Arabidopsis thaliana, 308.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:806696-807706:- gene-YOR261C_AKU4011 rna-NM_001183680.3_AKU4011 cds-NP_014904.3_AKU4011 98.4 99.4 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000123.1:208724-209734:- gene-YOR261C_BG1 rna-NM_001183680.3_BG1 cds-NP_014904.3_BG1 98.4 99.4 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:792149-793165:- gene-YOR261C_Bruggeman rna-NM_001183680.3_Bruggeman cds-NP_014904.3_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:792802-793818:- gene-YOR261C_CAT1 rna-NM_001183680.3_CAT1 cds-NP_014904.3_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:789679-790689:- gene-YOR261C_CBS1585 rna-NM_001183680.3_CBS1585 cds-NP_014904.3_CBS1585 98.4 99.4 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:788367-789383:- gene-YOR261C_CBS436 rna-NM_001183680.3_CBS436 cds-NP_014904.3_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:786464-787474:- gene-YOR261C_CBS6412 rna-NM_001183680.3_CBS6412 cds-NP_014904.3_CBS6412 98.4 99.4 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:795441-796451:- gene-YOR261C_CBS6413 rna-NM_001183680.3_CBS6413 cds-NP_014904.3_CBS6413 98.4 99.4 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:815676-816692:- gene-YOR261C_CENPK1137D rna-NM_001183680.3_CENPK1137D cds-NP_014904.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:782809-783819:- gene-YOR261C_EthanolRed rna-NM_001183680.3_EthanolRed cds-NP_014904.3_EthanolRed 98.3 99.4 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:788208-789218:- gene-YOR261C_FaliES1 rna-NM_001183680.3_FaliES1 cds-NP_014904.3_FaliES1 98.3 99.4 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000381.1:37618-38628:+ gene-YOR261C_JAY291 rna-NM_001183680.3_JAY291 cds-NP_014904.3_JAY291 98.6 99.4 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:796431-797441:- gene-YOR261C_MUCL30387 rna-NM_001183680.3_MUCL30387 cds-NP_014904.3_MUCL30387 98.4 99.4 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:803547-804557:- gene-YOR261C_MUCL30388 rna-NM_001183680.3_MUCL30388 cds-NP_014904.3_MUCL30388 98.5 99.4 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:797013-798023:- gene-YOR261C_MUCL39482 rna-NM_001183680.3_MUCL39482 cds-NP_014904.3_MUCL39482 98.4 99.4 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:806594-807610:- gene-YOR261C_MUCL42920 rna-NM_001183680.3_MUCL42920 cds-NP_014904.3_MUCL42920 99.3 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:815804-816820:- gene-YOR261C_NCIM3186 rna-NM_001183680.3_NCIM3186 cds-NP_014904.3_NCIM3186 98.8 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:797108-798118:- gene-YOR261C_NCYC1407 rna-NM_001183680.3_NCYC1407 cds-NP_014904.3_NCYC1407 98.4 99.4 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:796406-797416:- gene-YOR261C_PE2H3 rna-NM_001183680.3_PE2H3 cds-NP_014904.3_PE2H3 98.6 99.4 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:806783-807793:- gene-YOR261C_PE2H4 rna-NM_001183680.3_PE2H4 cds-NP_014904.3_PE2H4 98.6 99.4 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:815915-816931:- gene-YOR261C_S288C rna-NM_001183680.3_S288C cds-NP_014904.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000006.1:225905-226921:- gene-YOR261C_SA1 rna-NM_001183680.3_SA1 cds-NP_014904.3_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:787391-788401:- gene-YOR261C_ThermosaccDry rna-NM_001183680.3_ThermosaccDry cds-NP_014904.3_ThermosaccDry 98.3 99.4 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:850846-851856:- gene-YOR261C_VR1 rna-NM_001183680.3_VR1 cds-NP_014904.3_VR1 98.6 99.4 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:520312-521322:- gene-YOR261C_ZTW1 rna-NM_001183680.3_ZTW1 cds-NP_014904.3_ZTW1 98.5 99.4 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:793185-794195:- gene-YOR261C_Sparadoxus rna-NM_001183680.3_Sparadoxus cds-NP_014904.3_Sparadoxus 91.1 99.4 Verified 1 1 1 False True False False False

Additional files