Gene name: RPN6
Reference locus (S288C): YDL097C
Gene biotype: protein_coding
Description: Essential, non-ATPase regulatory subunit of the 26S proteasome lid; required for the assembly and activity of the 26S proteasome; the human homolog (S9 protein) partially rescues Rpn6p depletion; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): RPN9 (0.999); RPN10 (0.999); RPN11 (0.999); RPN12 (0.999); PRE2 (0.999); RPN5 (0.999); UBP6 (0.999); RPT5 (0.999); PUP1 (0.999); RPN8 (0.999); RPN7 (0.999); PRE3 (0.999); PRE6 (0.999); PUP2 (0.999); PRE9 (0.999); RPN1 (0.999); SEM1 (0.999); PRE5 (0.999); RPT2 (0.999); SCL1 (0.999)
Homologues (species, bitscore): PSMD11 (Homo sapiens, 337.0); Psmd11 (Mus musculus, 337.4); psmd11b (Danio rerio, 336.3); psmd11 (Xenopus tropicalis, 334.0); Rpn6 (Drosophila melanogaster, 353.2); rpn-6.1 (Caenorhabditis elegans, 301.2); ATS9 (Arabidopsis thaliana, 334.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:270005-271309:- | gene-YDL097C_AKU4011 | rna-NM_001180156.1_AKU4011 | cds-NP_010186.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:278635-279939:+ | gene-YDL097C_BG1 | rna-NM_001180156.1_BG1 | cds-NP_010186.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:287428-288732:- | gene-YDL097C_Bruggeman | rna-NM_001180156.1_Bruggeman | cds-NP_010186.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:284165-285469:- | gene-YDL097C_CAT1 | rna-NM_001180156.1_CAT1 | cds-NP_010186.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:268277-269581:- | gene-YDL097C_CBS1585 | rna-NM_001180156.1_CBS1585 | cds-NP_010186.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:284943-286247:- | gene-YDL097C_CBS436 | rna-NM_001180156.1_CBS436 | cds-NP_010186.1_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:266704-268008:- | gene-YDL097C_CBS6412 | rna-NM_001180156.1_CBS6412 | cds-NP_010186.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:286329-287633:- | gene-YDL097C_CBS6413 | rna-NM_001180156.1_CBS6413 | cds-NP_010186.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:284213-285517:- | gene-YDL097C_CENPK1137D | rna-NM_001180156.1_CENPK1137D | cds-NP_010186.1_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:281039-282343:- | gene-YDL097C_EthanolRed | rna-NM_001180156.1_EthanolRed | cds-NP_010186.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:287011-288315:- | gene-YDL097C_FaliES1 | rna-NM_001180156.1_FaliES1 | cds-NP_010186.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000010.1:57060-58364:- | gene-YDL097C_JAY291 | rna-NM_001180156.1_JAY291 | cds-NP_010186.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:285191-286495:- | gene-YDL097C_MUCL30387 | rna-NM_001180156.1_MUCL30387 | cds-NP_010186.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:275966-277270:- | gene-YDL097C_MUCL30388 | rna-NM_001180156.1_MUCL30388 | cds-NP_010186.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:269381-270685:- | gene-YDL097C_MUCL39482 | rna-NM_001180156.1_MUCL39482 | cds-NP_010186.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:191143-192447:- | gene-YDL097C_MUCL42920 | rna-NM_001180156.1_MUCL42920 | cds-NP_010186.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:285314-286618:- | gene-YDL097C_NCIM3186 | rna-NM_001180156.1_NCIM3186 | cds-NP_010186.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:269397-270701:- | gene-YDL097C_NCYC1407 | rna-NM_001180156.1_NCYC1407 | cds-NP_010186.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:276177-277481:- | gene-YDL097C_PE2H3 | rna-NM_001180156.1_PE2H3 | cds-NP_010186.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:276177-277481:- | gene-YDL097C_PE2H4 | rna-NM_001180156.1_PE2H4 | cds-NP_010186.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:285391-286695:- | gene-YDL097C_S288C | rna-NM_001180156.1_S288C | cds-NP_010186.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000010.1:148223-149527:+ | gene-YDL097C_SA1 | rna-NM_001180156.1_SA1 | cds-NP_010186.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:286522-287826:- | gene-YDL097C_ThermosaccDry | rna-NM_001180156.1_ThermosaccDry | cds-NP_010186.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:288595-289899:- | gene-YDL097C_VR1 | rna-NM_001180156.1_VR1 | cds-NP_010186.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:284442-285746:- | gene-YDL097C_ZTW1 | rna-NM_001180156.1_ZTW1 | cds-NP_010186.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:286568-287869:- | gene-YDL097C_Sparadoxus | rna-NM_001180156.1_Sparadoxus | cds-NP_010186.1_Sparadoxus | 91.3 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |