RPN3 (YER021W)


Gene profile

Gene name: RPN3
Reference locus (S288C): YER021W
Gene biotype: protein_coding

Description: Essential non-ATPase regulatory subunit of the 26S proteasome lid; similar to the p58 subunit of the human 26S proteasome; temperature-sensitive alleles cause metaphase arrest, suggesting a role for the proteasome in cell cycle control

Top 10 interactors (score): RPN6 (0.999); RPN1 (0.999); PRE5 (0.999); RPT2 (0.999); RPT5 (0.999); SCL1 (0.999); PRE9 (0.999); PUP2 (0.999); PRE6 (0.999); RPN10 (0.999); RPN11 (0.999); RPN12 (0.999); PRE2 (0.999); RPN5 (0.999); UBP6 (0.999); RPN9 (0.999); PUP1 (0.999); RPN8 (0.999); RPN7 (0.999); PRE3 (0.999)

Homologues (species, bitscore): PSMD3 (Homo sapiens, 270.8); Psmd3 (Mus musculus, 270.0); psmd3 (Danio rerio, 275.0); psmd3 (Xenopus tropicalis, 265.0); Rpn3 (Drosophila melanogaster, 255.0); rpn-3 (Caenorhabditis elegans, 209.5); AT1G75990 (Arabidopsis thaliana, 241.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:190980-192551:+ gene-YER021W_AKU4011 rna-NM_001178912.1_AKU4011 cds-NP_010938.1_AKU4011 99.3 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000011.1:233537-235108:- gene-YER021W_BG1 rna-NM_001178912.1_BG1 cds-NP_010938.1_BG1 99.1 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:198837-200408:+ gene-YER021W_Bruggeman rna-NM_001178912.1_Bruggeman cds-NP_010938.1_Bruggeman 99.2 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:193729-195300:+ gene-YER021W_CAT1 rna-NM_001178912.1_CAT1 cds-NP_010938.1_CAT1 99.1 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:190903-192474:+ gene-YER021W_CBS1585 rna-NM_001178912.1_CBS1585 cds-NP_010938.1_CBS1585 99.2 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:192491-194062:+ gene-YER021W_CBS436 rna-NM_001178912.1_CBS436 cds-NP_010938.1_CBS436 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:191147-192718:+ gene-YER021W_CBS6412 rna-NM_001178912.1_CBS6412 cds-NP_010938.1_CBS6412 99.2 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:195933-197504:+ gene-YER021W_CBS6413 rna-NM_001178912.1_CBS6413 cds-NP_010938.1_CBS6413 99.3 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:194847-196418:+ gene-YER021W_CENPK1137D rna-NM_001178912.1_CENPK1137D cds-NP_010938.1_CENPK1137D 99.1 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:191609-193180:+ gene-YER021W_EthanolRed rna-NM_001178912.1_EthanolRed cds-NP_010938.1_EthanolRed 99.2 100.0 Mismatch 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:191868-193439:+ gene-YER021W_FaliES1 rna-NM_001178912.1_FaliES1 cds-NP_010938.1_FaliES1 99.2 100.0 Mismatch 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000024.1:58492-60063:+ gene-YER021W_JAY291 rna-NM_001178912.1_JAY291 cds-NP_010938.1_JAY291 99.1 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:195047-196618:+ gene-YER021W_MUCL30387 rna-NM_001178912.1_MUCL30387 cds-NP_010938.1_MUCL30387 99.1 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:191282-192853:+ gene-YER021W_MUCL30388 rna-NM_001178912.1_MUCL30388 cds-NP_010938.1_MUCL30388 99.3 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:189947-191518:+ gene-YER021W_MUCL39482 rna-NM_001178912.1_MUCL39482 cds-NP_010938.1_MUCL39482 99.3 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:197033-198604:+ gene-YER021W_MUCL42920 rna-NM_001178912.1_MUCL42920 cds-NP_010938.1_MUCL42920 99.2 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:196947-198518:+ gene-YER021W_NCIM3186 rna-NM_001178912.1_NCIM3186 cds-NP_010938.1_NCIM3186 99.1 100.0 Mismatch 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:195018-196589:+ gene-YER021W_NCYC1407 rna-NM_001178912.1_NCYC1407 cds-NP_010938.1_NCYC1407 99.3 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:199333-200904:+ gene-YER021W_PE2H3 rna-NM_001178912.1_PE2H3 cds-NP_010938.1_PE2H3 99.1 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:195233-196804:+ gene-YER021W_PE2H4 rna-NM_001178912.1_PE2H4 cds-NP_010938.1_PE2H4 99.1 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:196948-198519:+ gene-YER021W_S288C rna-NM_001178912.1_S288C cds-NP_010938.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000020.1:45166-46737:- gene-YER021W_SA1 rna-NM_001178912.1_SA1 cds-NP_010938.1_SA1 99.1 100.0 Mismatch 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:192639-194210:+ gene-YER021W_ThermosaccDry rna-NM_001178912.1_ThermosaccDry cds-NP_010938.1_ThermosaccDry 99.1 100.0 Mismatch 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:191393-192964:+ gene-YER021W_VR1 rna-NM_001178912.1_VR1 cds-NP_010938.1_VR1 99.1 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000009.1:189850-191421:+ gene-YER021W_ZTW1 rna-NM_001178912.1_ZTW1 cds-NP_010938.1_ZTW1 99.3 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:193576-195147:+ gene-YER021W_Sparadoxus rna-NM_001178912.1_Sparadoxus cds-NP_010938.1_Sparadoxus 92.2 100.0 Verified 1 1 1 False True False False False

Additional files