Gene name: RPN14
Reference locus (S288C): YGL004C
Gene biotype: protein_coding
Description: 26S proteasome regulatory subunit RPN14; Evolutionarily conserved 19S regulatory particle assembly-chaperone; proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasome regulatory particle (RP); null mutants accumulate ubiquitinated Gcn4p and display decreased 26S proteasome stability; interacts with Rpt5p
Top 10 interactors (score): NAS6 (0.999); RPT3 (0.997); RPT6 (0.997); RPN8 (0.993); HSM3 (0.991); RPT1 (0.991); NAS2 (0.986); RPT5 (0.979); RPN11 (0.968); RPT4 (0.967); RPT2 (0.963); RPN10 (0.946); RPN5 (0.945); RPN13 (0.943); RPN1 (0.936); RPN3 (0.881); RPN9 (0.873); ECM29 (0.873); RPN2 (0.868); RPN12 (0.862)
Homologues (species, bitscore): PAAF1 (Homo sapiens, 110.5); Tbl1x (Mus musculus, 67.0); wdr5 (Danio rerio, 67.0); thul16 (Xenopus tropicalis, 129.0); wds (Drosophila melanogaster, 68.9); Y39G10AR.9 (Caenorhabditis elegans, 71.6); AT1G10580 (Arabidopsis thaliana, 63.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:492754-494007:- | gene-YGL004C_AKU4011 | rna-NM_001180869.3_AKU4011 | cds-NP_011511.3_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000060.1:82103-83356:+ | gene-YGL004C_BG1 | rna-NM_001180869.3_BG1 | cds-NP_011511.3_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:493723-494976:- | gene-YGL004C_Bruggeman | rna-NM_001180869.3_Bruggeman | cds-NP_011511.3_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:492266-493519:- | gene-YGL004C_CAT1 | rna-NM_001180869.3_CAT1 | cds-NP_011511.3_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:494227-495480:- | gene-YGL004C_CBS1585 | rna-NM_001180869.3_CBS1585 | cds-NP_011511.3_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:488609-489862:- | gene-YGL004C_CBS436 | rna-NM_001180869.3_CBS436 | cds-NP_011511.3_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:486843-488096:- | gene-YGL004C_CBS6412 | rna-NM_001180869.3_CBS6412 | cds-NP_011511.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:490898-492151:- | gene-YGL004C_CBS6413 | rna-NM_001180869.3_CBS6413 | cds-NP_011511.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:490520-491773:- | gene-YGL004C_CENPK1137D | rna-NM_001180869.3_CENPK1137D | cds-NP_011511.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:481125-482378:- | gene-YGL004C_EthanolRed | rna-NM_001180869.3_EthanolRed | cds-NP_011511.3_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:484377-485630:- | gene-YGL004C_FaliES1 | rna-NM_001180869.3_FaliES1 | cds-NP_011511.3_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000020.1:23007-24260:- | gene-YGL004C_JAY291 | rna-NM_001180869.3_JAY291 | cds-NP_011511.3_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:490945-492198:- | gene-YGL004C_MUCL30387 | rna-NM_001180869.3_MUCL30387 | cds-NP_011511.3_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:493496-494749:- | gene-YGL004C_MUCL30388 | rna-NM_001180869.3_MUCL30388 | cds-NP_011511.3_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:490066-491319:- | gene-YGL004C_MUCL39482 | rna-NM_001180869.3_MUCL39482 | cds-NP_011511.3_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:499497-500750:- | gene-YGL004C_MUCL42920 | rna-NM_001180869.3_MUCL42920 | cds-NP_011511.3_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:490703-491956:- | gene-YGL004C_NCIM3186 | rna-NM_001180869.3_NCIM3186 | cds-NP_011511.3_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:484086-485339:- | gene-YGL004C_NCYC1407 | rna-NM_001180869.3_NCYC1407 | cds-NP_011511.3_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:486776-488029:- | gene-YGL004C_PE2H3 | rna-NM_001180869.3_PE2H3 | cds-NP_011511.3_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:491826-493079:- | gene-YGL004C_PE2H4 | rna-NM_001180869.3_PE2H4 | cds-NP_011511.3_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:490703-491956:- | gene-YGL004C_S288C | rna-NM_001180869.3_S288C | cds-NP_011511.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000021.1:63626-64879:+ | gene-YGL004C_SA1 | rna-NM_001180869.3_SA1 | cds-NP_011511.3_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:503702-504955:- | gene-YGL004C_ThermosaccDry | rna-NM_001180869.3_ThermosaccDry | cds-NP_011511.3_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:593738-594991:- | gene-YGL004C_VR1 | rna-NM_001180869.3_VR1 | cds-NP_011511.3_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:482301-483554:- | gene-YGL004C_ZTW1 | rna-NM_001180869.3_ZTW1 | cds-NP_011511.3_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:491901-493154:- | gene-YGL004C_Sparadoxus | rna-NM_001180869.3_Sparadoxus | cds-NP_011511.3_Sparadoxus | 88.0 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |