RPN13 (YLR421C)


Gene profile

Gene name: RPN13
Reference locus (S288C): YLR421C
Gene biotype: protein_coding

Description: Subunit of the 19S regulatory particle of the 26S proteasome lid; acts as a ubiquitin receptor for the proteasome; null mutants accumulate ubiquitinated Gcn4p and display decreased 26S proteasome stability; protein abundance increases in response to DNA replication stress; Belongs to the RPN13 family

Top 10 interactors (score): RPN5 (0.999); RPT2 (0.999); RPN10 (0.999); RPT1 (0.999); RPN2 (0.999); SEM1 (0.999); RPN6 (0.999); RPN11 (0.999); PRE4 (0.999); RPT3 (0.999); PRE9 (0.999); RPT4 (0.999); PRE1 (0.999); PRE7 (0.999); PUP2 (0.999); PRE8 (0.999); RPN3 (0.999); PRE6 (0.999); RPT6 (0.999); PRE10 (0.999)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:908639-909109:- gene-YLR421C_AKU4011 rna-NM_001182309.3_AKU4011 cds-NP_013525.3_AKU4011 99.7 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000048.1:140804-141274:- gene-YLR421C_BG1 rna-NM_001182309.3_BG1 cds-NP_013525.3_BG1 98.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:946942-947412:- gene-YLR421C_Bruggeman rna-NM_001182309.3_Bruggeman cds-NP_013525.3_Bruggeman 98.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:942489-942959:- gene-YLR421C_CAT1 rna-NM_001182309.3_CAT1 cds-NP_013525.3_CAT1 98.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:944236-944706:- gene-YLR421C_CBS1585 rna-NM_001182309.3_CBS1585 cds-NP_013525.3_CBS1585 99.7 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:927893-928363:- gene-YLR421C_CBS436 rna-NM_001182309.3_CBS436 cds-NP_013525.3_CBS436 98.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:980276-980746:- gene-YLR421C_CBS6412 rna-NM_001182309.3_CBS6412 cds-NP_013525.3_CBS6412 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:944528-944998:- gene-YLR421C_CBS6413 rna-NM_001182309.3_CBS6413 cds-NP_013525.3_CBS6413 99.7 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:944290-944760:- gene-YLR421C_CENPK1137D rna-NM_001182309.3_CENPK1137D cds-NP_013525.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:901519-901989:- gene-YLR421C_EthanolRed rna-NM_001182309.3_EthanolRed cds-NP_013525.3_EthanolRed 99.7 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:931000-931470:- gene-YLR421C_FaliES1 rna-NM_001182309.3_FaliES1 cds-NP_013525.3_FaliES1 99.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000434.1:83633-84103:- gene-YLR421C_JAY291 rna-NM_001182309.3_JAY291 cds-NP_013525.3_JAY291 98.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:945805-946275:- gene-YLR421C_MUCL30387 rna-NM_001182309.3_MUCL30387 cds-NP_013525.3_MUCL30387 98.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:951908-952378:- gene-YLR421C_MUCL30388 rna-NM_001182309.3_MUCL30388 cds-NP_013525.3_MUCL30388 99.5 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:945456-945926:- gene-YLR421C_MUCL39482 rna-NM_001182309.3_MUCL39482 cds-NP_013525.3_MUCL39482 99.7 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:940113-940583:- gene-YLR421C_MUCL42920 rna-NM_001182309.3_MUCL42920 cds-NP_013525.3_MUCL42920 98.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:965064-965534:- gene-YLR421C_NCIM3186 rna-NM_001182309.3_NCIM3186 cds-NP_013525.3_NCIM3186 98.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:954635-955105:- gene-YLR421C_NCYC1407 rna-NM_001182309.3_NCYC1407 cds-NP_013525.3_NCYC1407 99.7 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:941014-941484:- gene-YLR421C_PE2H3 rna-NM_001182309.3_PE2H3 cds-NP_013525.3_PE2H3 98.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:940758-941228:- gene-YLR421C_PE2H4 rna-NM_001182309.3_PE2H4 cds-NP_013525.3_PE2H4 98.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:965090-965560:- gene-YLR421C_S288C rna-NM_001182309.3_S288C cds-NP_013525.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000007.1:89113-89583:+ gene-YLR421C_SA1 rna-NM_001182309.3_SA1 cds-NP_013525.3_SA1 99.7 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:934079-934549:- gene-YLR421C_ThermosaccDry rna-NM_001182309.3_ThermosaccDry cds-NP_013525.3_ThermosaccDry 99.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:946456-946926:- gene-YLR421C_VR1 rna-NM_001182309.3_VR1 cds-NP_013525.3_VR1 99.7 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000025.1:270292-270762:- gene-YLR421C_ZTW1 rna-NM_001182309.3_ZTW1 cds-NP_013525.3_ZTW1 99.5 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:919491-919964:- gene-YLR421C_Sparadoxus rna-NM_001182309.3_Sparadoxus cds-NP_013525.3_Sparadoxus 89.2 100.0 Verified 1 1 0 False False True False False

Additional files