Gene name: RPN12
Reference locus (S288C): YFR052W
Gene biotype: protein_coding
Description: Subunit of the 19S regulatory particle of the 26S proteasome lid; synthetically lethal with RPT1, which is an ATPase component of the 19S regulatory particle; physically interacts with Nob1p and Rpn3p; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): PRE3 (0.999); RPT3 (0.999); PRE4 (0.999); SCL1 (0.999); RPT2 (0.999); PRE5 (0.999); RPN1 (0.999); RPN11 (0.999); RPN10 (0.999); PRE6 (0.999); PUP2 (0.999); PRE9 (0.999); RPN7 (0.999); RPT5 (0.999); PUP1 (0.999); RPN8 (0.999); RPN9 (0.999); UBP6 (0.999); RPN5 (0.999); PRE2 (0.999)
Homologues (species, bitscore): PSMD8 (Homo sapiens, 121.7); Psmd8 (Mus musculus, 121.7); psmd8 (Danio rerio, 123.2); psmd8 (Xenopus tropicalis, 113.6); Rpn12 (Drosophila melanogaster, 96.7); rpn-12 (Caenorhabditis elegans, 81.6); RPN12a (Arabidopsis thaliana, 115.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005300.1:242655-243479:+ | gene-YFR052W_AKU4011 | rna-NM_001180017.1_AKU4011 | cds-NP_116710.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000071.1:17530-18354:- | gene-YFR052W_BG1 | rna-NM_001180017.1_BG1 | cds-NP_116710.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005508.1:246307-247131:+ | gene-YFR052W_Bruggeman | rna-NM_001180017.1_Bruggeman | cds-NP_116710.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005524.1:248281-249105:+ | gene-YFR052W_CAT1 | rna-NM_001180017.1_CAT1 | cds-NP_116710.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005364.1:244155-244979:+ | gene-YFR052W_CBS1585 | rna-NM_001180017.1_CBS1585 | cds-NP_116710.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005348.1:217116-217940:+ | gene-YFR052W_CBS436 | rna-NM_001180017.1_CBS436 | cds-NP_116710.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005332.1:243229-244053:+ | gene-YFR052W_CBS6412 | rna-NM_001180017.1_CBS6412 | cds-NP_116710.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005316.1:245903-246727:+ | gene-YFR052W_CBS6413 | rna-NM_001180017.1_CBS6413 | cds-NP_116710.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001527.1:248592-249416:+ | gene-YFR052W_CENPK1137D | rna-NM_001180017.1_CENPK1137D | cds-NP_116710.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005476.1:241774-242598:+ | gene-YFR052W_EthanolRed | rna-NM_001180017.1_EthanolRed | cds-NP_116710.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005540.1:243424-244248:+ | gene-YFR052W_FaliES1 | rna-NM_001180017.1_FaliES1 | cds-NP_116710.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000453.1:46554-47378:+ | gene-YFR052W_JAY291 | rna-NM_001180017.1_JAY291 | cds-NP_116710.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005412.1:246755-247579:+ | gene-YFR052W_MUCL30387 | rna-NM_001180017.1_MUCL30387 | cds-NP_116710.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005444.1:242236-243060:+ | gene-YFR052W_MUCL30388 | rna-NM_001180017.1_MUCL30388 | cds-NP_116710.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005284.1:242077-242901:+ | gene-YFR052W_MUCL39482 | rna-NM_001180017.1_MUCL39482 | cds-NP_116710.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005428.1:241675-242499:+ | gene-YFR052W_MUCL42920 | rna-NM_001180017.1_MUCL42920 | cds-NP_116710.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011815.1:252504-253328:+ | gene-YFR052W_NCIM3186 | rna-NM_001180017.1_NCIM3186 | cds-NP_116710.1_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005268.1:242927-243751:+ | gene-YFR052W_NCYC1407 | rna-NM_001180017.1_NCYC1407 | cds-NP_116710.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994145.1:284964-285788:+ | gene-YFR052W_PE2H3 | rna-NM_001180017.1_PE2H3 | cds-NP_116710.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999877.1:284512-285336:+ | gene-YFR052W_PE2H4 | rna-NM_001180017.1_PE2H4 | cds-NP_116710.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001138.5:252505-253329:+ | gene-YFR052W_S288C | rna-NM_001180017.1_S288C | cds-NP_116710.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000086.1:17773-18597:- | gene-YFR052W_SA1 | rna-NM_001180017.1_SA1 | cds-NP_116710.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005492.1:242593-243417:+ | gene-YFR052W_ThermosaccDry | rna-NM_001180017.1_ThermosaccDry | cds-NP_116710.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005460.1:258348-259172:+ | gene-YFR052W_VR1 | rna-NM_001180017.1_VR1 | cds-NP_116710.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000013.1:173039-173863:+ | gene-YFR052W_ZTW1 | rna-NM_001180017.1_ZTW1 | cds-NP_116710.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047492.1:266072-266896:+ | gene-YFR052W_Sparadoxus | rna-NM_001180017.1_Sparadoxus | cds-NP_116710.1_Sparadoxus | 92.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |