Gene name: RPN11
Reference locus (S288C): YFR004W
Gene biotype: protein_coding
Description: Ubiquitin carboxyl-terminal hydrolase RPN11; Metalloprotease subunit of 19S regulatory particle; part of 26S proteasome lid; couples the deubiquitination and degradation of proteasome substrates; involved, independent of catalytic activity, in fission of mitochondria and peroxisomes; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): RPN13 (0.999); PRE10 (0.999); RPT6 (0.999); RPT1 (0.999); RPN2 (0.999); CDC48 (0.999); RPN6 (0.999); SEM1 (0.999); PRE8 (0.999); RPN3 (0.999); PUP3 (0.999); PRE1 (0.999); RPN1 (0.999); ECM29 (0.999); RPT2 (0.999); SCL1 (0.999); RPT4 (0.999); RPT3 (0.999); PRE4 (0.999); PRE7 (0.999)
Homologues (species, bitscore): PSMD14 (Homo sapiens, 414.8); Psmd14 (Mus musculus, 414.8); psmd14 (Danio rerio, 412.1); psmd14 (Xenopus tropicalis, 411.8); Rpn11 (Drosophila melanogaster, 414.5); rpn-11 (Caenorhabditis elegans, 395.2); AT5G23540 (Arabidopsis thaliana, 398.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005300.1:143839-144759:+ | gene-YFR004W_AKU4011 | rna-NM_001179969.1_AKU4011 | cds-NP_116659.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000079.1:28734-29654:+ | gene-YFR004W_BG1 | rna-NM_001179969.1_BG1 | cds-NP_116659.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005508.1:143405-144325:+ | gene-YFR004W_Bruggeman | rna-NM_001179969.1_Bruggeman | cds-NP_116659.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005524.1:148570-149490:+ | gene-YFR004W_CAT1 | rna-NM_001179969.1_CAT1 | cds-NP_116659.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005364.1:144664-145584:+ | gene-YFR004W_CBS1585 | rna-NM_001179969.1_CBS1585 | cds-NP_116659.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005348.1:118511-119431:+ | gene-YFR004W_CBS436 | rna-NM_001179969.1_CBS436 | cds-NP_116659.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005332.1:144405-145325:+ | gene-YFR004W_CBS6412 | rna-NM_001179969.1_CBS6412 | cds-NP_116659.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005316.1:146915-147835:+ | gene-YFR004W_CBS6413 | rna-NM_001179969.1_CBS6413 | cds-NP_116659.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001527.1:149528-150448:+ | gene-YFR004W_CENPK1137D | rna-NM_001179969.1_CENPK1137D | cds-NP_116659.1_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005476.1:142825-143745:+ | gene-YFR004W_EthanolRed | rna-NM_001179969.1_EthanolRed | cds-NP_116659.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005540.1:144472-145392:+ | gene-YFR004W_FaliES1 | rna-NM_001179969.1_FaliES1 | cds-NP_116659.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000451.1:8579-9499:+ | gene-YFR004W_JAY291 | rna-NM_001179969.1_JAY291 | cds-NP_116659.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005412.1:145036-145956:+ | gene-YFR004W_MUCL30387 | rna-NM_001179969.1_MUCL30387 | cds-NP_116659.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005444.1:143012-143932:+ | gene-YFR004W_MUCL30388 | rna-NM_001179969.1_MUCL30388 | cds-NP_116659.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005284.1:143108-144028:+ | gene-YFR004W_MUCL39482 | rna-NM_001179969.1_MUCL39482 | cds-NP_116659.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005428.1:142371-143291:+ | gene-YFR004W_MUCL42920 | rna-NM_001179969.1_MUCL42920 | cds-NP_116659.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011815.1:153392-154312:+ | gene-YFR004W_NCIM3186 | rna-NM_001179969.1_NCIM3186 | cds-NP_116659.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005268.1:144123-145043:+ | gene-YFR004W_NCYC1407 | rna-NM_001179969.1_NCYC1407 | cds-NP_116659.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994145.1:163189-164109:+ | gene-YFR004W_PE2H3 | rna-NM_001179969.1_PE2H3 | cds-NP_116659.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999877.1:162737-163657:+ | gene-YFR004W_PE2H4 | rna-NM_001179969.1_PE2H4 | cds-NP_116659.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001138.5:153393-154313:+ | gene-YFR004W_S288C | rna-NM_001179969.1_S288C | cds-NP_116659.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000011.1:169913-170833:- | gene-YFR004W_SA1 | rna-NM_001179969.1_SA1 | cds-NP_116659.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005492.1:143632-144552:+ | gene-YFR004W_ThermosaccDry | rna-NM_001179969.1_ThermosaccDry | cds-NP_116659.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005460.1:158836-159756:+ | gene-YFR004W_VR1 | rna-NM_001179969.1_VR1 | cds-NP_116659.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000013.1:74082-75002:+ | gene-YFR004W_ZTW1 | rna-NM_001179969.1_ZTW1 | cds-NP_116659.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047492.1:167298-168218:+ | gene-YFR004W_Sparadoxus | rna-NM_001179969.1_Sparadoxus | cds-NP_116659.1_Sparadoxus | 93.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |