Gene name: RPL8B
Reference locus (S288C): YLL045C
Gene biotype: protein_coding
Description: Ribosomal 60S subunit protein L8B; required for processing of 27SA3 pre-rRNA to 27SB pre-rRNA during assembly of large ribosomal subunit; depletion leads to a turnover of pre-rRNA; L8 binds to Domain I of 25S and 5.8 S rRNAs; mutation results in decreased amounts of free 60S subunits; homologous to mammalian ribosomal protein L7A, no bacterial homolog; RPL8B has a paralog, RPL8A, that arose from the whole genome duplication
Top 10 interactors (score): RPL42B (0.999); RPS7B (0.999); RPS17A (0.999); RPS20 (0.999); RPL11A (0.999); RPL8A (0.999); RPS1B (0.999); RPL25 (0.999); RPL22A (0.999); RPS25A (0.999); RPL35B (0.999); RPL10 (0.999); RPS31 (0.999); RPL18A (0.999); RPL24B (0.999); RPS0A (0.999); RPL21A (0.999); RPL43A (0.999); RPL7A (0.999); ASC1 (0.999)
Homologues (species, bitscore): RPL7A (Homo sapiens, 296.2); Rpl7a (Mus musculus, 295.8); rpl7a (Danio rerio, 293.5); rpl7a (Xenopus tropicalis, 299.3); RpL7A (Drosophila melanogaster, 278.1); rpl-7A (Caenorhabditis elegans, 266.5); AT2G47610 (Arabidopsis thaliana, 283.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:35020-35790:- | gene-YLL045C_AKU4011 | rna-NM_001181865.1_AKU4011 | cds-NP_013055.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000104.1:222-992:+ | gene-YLL045C_BG1 | rna-NM_001181865.1_BG1 | cds-NP_013055.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:44364-45134:- | gene-YLL045C_Bruggeman | rna-NM_001181865.1_Bruggeman | cds-NP_013055.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:45890-46660:- | gene-YLL045C_CAT1 | rna-NM_001181865.1_CAT1 | cds-NP_013055.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:42931-43701:- | gene-YLL045C_CBS1585 | rna-NM_001181865.1_CBS1585 | cds-NP_013055.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:32928-33698:- | gene-YLL045C_CBS436 | rna-NM_001181865.1_CBS436 | cds-NP_013055.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:42591-43361:- | gene-YLL045C_CBS6412 | rna-NM_001181865.1_CBS6412 | cds-NP_013055.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:42734-43504:- | gene-YLL045C_CBS6413 | rna-NM_001181865.1_CBS6413 | cds-NP_013055.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:32842-33612:- | gene-YLL045C_CENPK1137D | rna-NM_001181865.1_CENPK1137D | cds-NP_013055.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:35646-36416:- | gene-YLL045C_EthanolRed | rna-NM_001181865.1_EthanolRed | cds-NP_013055.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:34967-35737:- | gene-YLL045C_FaliES1 | rna-NM_001181865.1_FaliES1 | cds-NP_013055.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000145.1:1-731:- | gene-YLL045C_JAY291 | rna-NM_001181865.1_JAY291 | cds-NP_013055.1_JAY291 | 94.4 | 94.8 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:42677-43447:- | gene-YLL045C_MUCL30387 | rna-NM_001181865.1_MUCL30387 | cds-NP_013055.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:46675-47445:- | gene-YLL045C_MUCL30388 | rna-NM_001181865.1_MUCL30388 | cds-NP_013055.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:42932-43702:- | gene-YLL045C_MUCL39482 | rna-NM_001181865.1_MUCL39482 | cds-NP_013055.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:43236-44006:- | gene-YLL045C_MUCL42920 | rna-NM_001181865.1_MUCL42920 | cds-NP_013055.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:47833-48603:- | gene-YLL045C_NCIM3186 | rna-NM_001181865.1_NCIM3186 | cds-NP_013055.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:34810-35580:- | gene-YLL045C_NCYC1407 | rna-NM_001181865.1_NCYC1407 | cds-NP_013055.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:41477-42247:- | gene-YLL045C_PE2H3 | rna-NM_001181865.1_PE2H3 | cds-NP_013055.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:41283-42053:- | gene-YLL045C_PE2H4 | rna-NM_001181865.1_PE2H4 | cds-NP_013055.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:47859-48629:- | gene-YLL045C_S288C | rna-NM_001181865.1_S288C | cds-NP_013055.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000047.1:41097-41867:- | gene-YLL045C_SA1 | rna-NM_001181865.1_SA1 | cds-NP_013055.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:35471-36241:- | gene-YLL045C_ThermosaccDry | rna-NM_001181865.1_ThermosaccDry | cds-NP_013055.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:49060-49830:- | gene-YLL045C_VR1 | rna-NM_001181865.1_VR1 | cds-NP_013055.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:34790-35560:- | gene-YLL045C_ZTW1 | rna-NM_001181865.1_ZTW1 | cds-NP_013055.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:43209-43979:- | gene-YLL045C_Sparadoxus | rna-NM_001181865.1_Sparadoxus | cds-NP_013055.1_Sparadoxus | 95.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |