Gene name: RPL8A
Reference locus (S288C): YHL033C
Gene biotype: protein_coding
Description: Ribosomal 60S subunit protein L8A; required for processing of 27SA3 pre-rRNA to 27SB pre-rRNA during assembly of large ribosomal subunit; depletion leads to a turnover of pre-rRNA; L8 binds to Domain I of 25S and 5.8 S rRNAs; mutation results in decreased amounts of free 60S subunits; homologous to mammalian ribosomal protein L7A, no bacterial homolog; RPL8A has a paralog, RPL8B, that arose from the whole genome duplication
Top 10 interactors (score): RPL24A (0.999); RPP0 (0.999); RPS19A (0.999); RPL16B (0.999); RPS8B (0.999); RPL33A (0.999); RPL42A (0.999); RPL19B (0.999); RPP2A (0.999); RPL39 (0.999); RPL34A (0.999); RPL18B (0.999); RPL20B (0.999); RPL17B (0.999); RPL29 (0.999); RPS17B (0.999); RPL17A (0.999); RPL23A (0.999); RPS26A (0.999); RPL40A (0.999)
Homologues (species, bitscore): RPL7A (Homo sapiens, 293.1); Rpl7a (Mus musculus, 293.1); rpl7a (Danio rerio, 291.6); rpl7a (Xenopus tropicalis, 297.7); RpL7A (Drosophila melanogaster, 278.9); rpl-7A (Caenorhabditis elegans, 261.9); AT2G47610 (Arabidopsis thaliana, 283.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:30109-30879:- | gene-YHL033C_AKU4011 | rna-NM_001179113.1_AKU4011 | cds-NP_011830.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000180.1:45948-46718:+ | gene-YHL033C_BG1 | rna-NM_001179113.1_BG1 | cds-NP_011830.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:36770-37540:- | gene-YHL033C_Bruggeman | rna-NM_001179113.1_Bruggeman | cds-NP_011830.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:31026-31796:- | gene-YHL033C_CAT1 | rna-NM_001179113.1_CAT1 | cds-NP_011830.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:30712-31482:- | gene-YHL033C_CBS1585 | rna-NM_001179113.1_CBS1585 | cds-NP_011830.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:23295-24065:- | gene-YHL033C_CBS436 | rna-NM_001179113.1_CBS436 | cds-NP_011830.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005334.1:30661-31431:- | gene-YHL033C_CBS6412 | rna-NM_001179113.1_CBS6412 | cds-NP_011830.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:30127-30897:- | gene-YHL033C_CBS6413 | rna-NM_001179113.1_CBS6413 | cds-NP_011830.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:28420-29190:- | gene-YHL033C_CENPK1137D | rna-NM_001179113.1_CENPK1137D | cds-NP_011830.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:30337-31107:- | gene-YHL033C_EthanolRed | rna-NM_001179113.1_EthanolRed | cds-NP_011830.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:30661-31431:- | gene-YHL033C_FaliES1 | rna-NM_001179113.1_FaliES1 | cds-NP_011830.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000157.1:22617-22690:- | gene-YHL033C_JAY291 | rna-NM_001179113.1_JAY291 | cds-NP_011830.1_JAY291 | 9.5 | 9.5 | Mismatch | 1 | 1 | 0 | False | False | True | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:32605-33375:- | gene-YHL033C_MUCL30387 | rna-NM_001179113.1_MUCL30387 | cds-NP_011830.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:34443-35213:- | gene-YHL033C_MUCL30388 | rna-NM_001179113.1_MUCL30388 | cds-NP_011830.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:29703-30473:- | gene-YHL033C_MUCL39482 | rna-NM_001179113.1_MUCL39482 | cds-NP_011830.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:33673-34443:- | gene-YHL033C_MUCL42920 | rna-NM_001179113.1_MUCL42920 | cds-NP_011830.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:35137-35907:- | gene-YHL033C_NCIM3186 | rna-NM_001179113.1_NCIM3186 | cds-NP_011830.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005270.1:29189-29959:- | gene-YHL033C_NCYC1407 | rna-NM_001179113.1_NCYC1407 | cds-NP_011830.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:25479-26249:- | gene-YHL033C_PE2H3 | rna-NM_001179113.1_PE2H3 | cds-NP_011830.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:32856-33626:- | gene-YHL033C_PE2H4 | rna-NM_001179113.1_PE2H4 | cds-NP_011830.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:35255-36025:- | gene-YHL033C_S288C | rna-NM_001179113.1_S288C | cds-NP_011830.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:19544-20314:- | gene-YHL033C_SA1 | rna-NM_001179113.1_SA1 | cds-NP_011830.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:31750-32520:- | gene-YHL033C_ThermosaccDry | rna-NM_001179113.1_ThermosaccDry | cds-NP_011830.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:36459-37229:- | gene-YHL033C_VR1 | rna-NM_001179113.1_VR1 | cds-NP_011830.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:22965-23735:- | gene-YHL033C_ZTW1 | rna-NM_001179113.1_ZTW1 | cds-NP_011830.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:29296-30066:- | gene-YHL033C_Sparadoxus | rna-NM_001179113.1_Sparadoxus | cds-NP_011830.1_Sparadoxus | 94.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |