RPL7A (YGL076C)


Gene profile

Gene name: RPL7A
Reference locus (S288C): YGL076C
Gene biotype: protein_coding

Description: Ribosomal 60S subunit protein L7A; required for processing of 27SA3 pre-rRNA to 27SB pre-rRNA during assembly of large ribosomal subunit; depletion leads to a turnover of pre-rRNA; contains a conserved C-terminal Nucleic acid Binding Domain (NDB2); binds to Domain II of 25S and 5.8S rRNAs; homologous to mammalian ribosomal protein L7 and bacterial L30; RPL7A has a paralog, RPL7B, that arose from the whole genome duplication

Top 10 interactors (score): RPL19A (0.999); RPS12 (0.999); RPL13B (0.999); RPS8A (0.999); RPS16B (0.999); RPS11A (0.999); RPS10A (0.999); RPL30 (0.999); RPS4B (0.999); RPL13A (0.999); RPL27B (0.999); RPL16A (0.999); RPS18A (0.999); RPL15A (0.999); RPL6A (0.999); RPL12A (0.999); RPS4A (0.999); RPL21B (0.999); RPS23A (0.999); RPL4B (0.999)

Homologues (species, bitscore): RPL7 (Homo sapiens, 250.4); Rpl7 (Mus musculus, 246.9); rpl7 (Danio rerio, 253.1); rpl7 (Xenopus tropicalis, 255.0); RpL7 (Drosophila melanogaster, 235.3); rpl-7 (Caenorhabditis elegans, 270.4); AT3G13580 (Arabidopsis thaliana, 276.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:367341-369009:- gene-YGL076C_AKU4011 rna-NM_001180941.1_AKU4011 cds-NP_011439.1_AKU4011 99.3 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000132.1:36401-38062:+ gene-YGL076C_BG1 rna-NM_001180941.1_BG1 cds-NP_011439.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:369824-371484:- gene-YGL076C_Bruggeman rna-NM_001180941.1_Bruggeman cds-NP_011439.1_Bruggeman 91.6 99.8 Unannotated 1 1 0 False False False True False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:366738-368487:- gene-YGL076C_CAT1 rna-NM_001180941.1_CAT1 cds-NP_011439.1_CAT1 89.1 100.0 Unannotated 1 1 0 False False False True False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:370666-372554:- gene-YGL076C_CBS1585 rna-NM_001180941.1_CBS1585 cds-NP_011439.1_CBS1585 76.5 100.0 Unannotated 1 1 0 False False False True False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:364949-366679:- gene-YGL076C_CBS436 rna-NM_001180941.1_CBS436 cds-NP_011439.1_CBS436 91.2 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:355046-356714:- gene-YGL076C_CBS6412 rna-NM_001180941.1_CBS6412 cds-NP_011439.1_CBS6412 99.3 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:364970-366638:- gene-YGL076C_CBS6413 rna-NM_001180941.1_CBS6413 cds-NP_011439.1_CBS6413 99.3 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:364524-366185:- gene-YGL076C_CENPK1137D rna-NM_001180941.1_CENPK1137D cds-NP_011439.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:356413-358081:- gene-YGL076C_EthanolRed rna-NM_001180941.1_EthanolRed cds-NP_011439.1_EthanolRed 99.4 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:358974-360642:- gene-YGL076C_FaliES1 rna-NM_001180941.1_FaliES1 cds-NP_011439.1_FaliES1 99.4 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000369.1:44677-46338:- gene-YGL076C_JAY291 rna-NM_001180941.1_JAY291 cds-NP_011439.1_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:366801-368680:- gene-YGL076C_MUCL30387 rna-NM_001180941.1_MUCL30387 cds-NP_011439.1_MUCL30387 76.9 100.0 Unannotated 1 1 0 False False False True False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:369786-371447:- gene-YGL076C_MUCL30388 rna-NM_001180941.1_MUCL30388 cds-NP_011439.1_MUCL30388 99.7 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:367194-368862:- gene-YGL076C_MUCL39482 rna-NM_001180941.1_MUCL39482 cds-NP_011439.1_MUCL39482 99.3 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:205251-206912:+ gene-YGL076C_MUCL42920 rna-NM_001180941.1_MUCL42920 cds-NP_011439.1_MUCL42920 99.1 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:364335-365996:- gene-YGL076C_NCIM3186 rna-NM_001180941.1_NCIM3186 cds-NP_011439.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:358729-360397:- gene-YGL076C_NCYC1407 rna-NM_001180941.1_NCYC1407 cds-NP_011439.1_NCYC1407 99.3 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:360377-362038:- gene-YGL076C_PE2H3 rna-NM_001180941.1_PE2H3 cds-NP_011439.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:365427-367088:- gene-YGL076C_PE2H4 rna-NM_001180941.1_PE2H4 cds-NP_011439.1_PE2H4 99.8 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:364335-365996:- gene-YGL076C_S288C rna-NM_001180941.1_S288C cds-NP_011439.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000096.1:1-1144:- gene-YGL076C_SA1 rna-NM_001180941.1_SA1 cds-NP_011439.1_SA1 29.5 29.5 Verified 1 1 0 False False False True False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:359227-360895:- gene-YGL076C_ThermosaccDry rna-NM_001180941.1_ThermosaccDry cds-NP_011439.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:469594-471263:- gene-YGL076C_VR1 rna-NM_001180941.1_VR1 cds-NP_011439.1_VR1 91.9 97.4 Verified 1 1 0 False False False True False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000014.1:356590-358258:- gene-YGL076C_ZTW1 rna-NM_001180941.1_ZTW1 cds-NP_011439.1_ZTW1 99.4 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:362207-363877:- gene-YGL076C_Sparadoxus rna-NM_001180941.1_Sparadoxus cds-NP_011439.1_Sparadoxus 95.7 100.0 Verified 1 1 1 False True False False False

Additional files