RPB7 (YDR404C)


Gene profile

Gene name: RPB7
Reference locus (S288C): YDR404C
Gene biotype: protein_coding

Description: RNA polymerase II subunit B16; forms dissociable heterodimer with Rpb4p; Rpb4/7 dissociates from RNAPII as Ser2 CTD phosphorylation increases; Rpb4/7 regulates cellular lifespan via mRNA decay process; involved in recruitment of 3'-end processing factors to transcribing RNA polymerase II complex, export of mRNA to cytoplasm under stress conditions; also involved in translation initiation

Top 10 interactors (score): RPB2 (0.999); RPB11 (0.999); RPB5 (0.999); ELF1 (0.999); RTR1 (0.999); SPT4 (0.999); RPB3 (0.999); RPO26 (0.999); SPT5 (0.999); SUA7 (0.999); RPC10 (0.999); RPB8 (0.999); RPO21 (0.999); RPB10 (0.999); RPB9 (0.999); DST1 (0.999); RPB4 (0.999); TFG2 (0.999); FCP1 (0.998); MED7 (0.997)

Homologues (species, bitscore): POLR2G (Homo sapiens, 148.3); Polr2g (Mus musculus, 148.3); polr2gl (Danio rerio, 147.5); polr2g (Xenopus tropicalis, 147.5); Rpb7 (Drosophila melanogaster, 143.7); rpb-7 (Caenorhabditis elegans, 141.0); NRPB7 (Arabidopsis thaliana, 138.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:1216800-1217315:- gene-YDR404C_AKU4011 rna-NM_001180712.3_AKU4011 cds-NP_010692.3_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000039.1:95284-95799:- gene-YDR404C_BG1 rna-NM_001180712.3_BG1 cds-NP_010692.3_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:1247685-1248200:- gene-YDR404C_Bruggeman rna-NM_001180712.3_Bruggeman cds-NP_010692.3_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:1226241-1226756:- gene-YDR404C_CAT1 rna-NM_001180712.3_CAT1 cds-NP_010692.3_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:1211720-1212235:- gene-YDR404C_CBS1585 rna-NM_001180712.3_CBS1585 cds-NP_010692.3_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:1230587-1231102:- gene-YDR404C_CBS436 rna-NM_001180712.3_CBS436 cds-NP_010692.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:1207774-1208289:- gene-YDR404C_CBS6412 rna-NM_001180712.3_CBS6412 cds-NP_010692.3_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:1229629-1230144:- gene-YDR404C_CBS6413 rna-NM_001180712.3_CBS6413 cds-NP_010692.3_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:1275314-1275829:- gene-YDR404C_CENPK1137D rna-NM_001180712.3_CENPK1137D cds-NP_010692.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:1221206-1221721:- gene-YDR404C_EthanolRed rna-NM_001180712.3_EthanolRed cds-NP_010692.3_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:1224516-1225031:- gene-YDR404C_FaliES1 rna-NM_001180712.3_FaliES1 cds-NP_010692.3_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000181.1:30501-31016:+ gene-YDR404C_JAY291 rna-NM_001180712.3_JAY291 cds-NP_010692.3_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:1231247-1231762:- gene-YDR404C_MUCL30387 rna-NM_001180712.3_MUCL30387 cds-NP_010692.3_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:1213353-1213868:- gene-YDR404C_MUCL30388 rna-NM_001180712.3_MUCL30388 cds-NP_010692.3_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:1203048-1203563:- gene-YDR404C_MUCL39482 rna-NM_001180712.3_MUCL39482 cds-NP_010692.3_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:1145486-1146001:- gene-YDR404C_MUCL42920 rna-NM_001180712.3_MUCL42920 cds-NP_010692.3_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:1276577-1277092:- gene-YDR404C_NCIM3186 rna-NM_001180712.3_NCIM3186 cds-NP_010692.3_NCIM3186 100.0 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:1217020-1217535:- gene-YDR404C_NCYC1407 rna-NM_001180712.3_NCYC1407 cds-NP_010692.3_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:1227153-1227668:- gene-YDR404C_PE2H3 rna-NM_001180712.3_PE2H3 cds-NP_010692.3_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:1232721-1233236:- gene-YDR404C_PE2H4 rna-NM_001180712.3_PE2H4 cds-NP_010692.3_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:1276654-1277169:- gene-YDR404C_S288C rna-NM_001180712.3_S288C cds-NP_010692.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000071.1:30618-31133:+ gene-YDR404C_SA1 rna-NM_001180712.3_SA1 cds-NP_010692.3_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:1228778-1229293:- gene-YDR404C_ThermosaccDry rna-NM_001180712.3_ThermosaccDry cds-NP_010692.3_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:1243959-1244474:- gene-YDR404C_VR1 rna-NM_001180712.3_VR1 cds-NP_010692.3_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000008.1:271579-272094:- gene-YDR404C_ZTW1 rna-NM_001180712.3_ZTW1 cds-NP_010692.3_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:1223978-1224493:- gene-YDR404C_Sparadoxus rna-NM_001180712.3_Sparadoxus cds-NP_010692.3_Sparadoxus 94.3 100.0 Verified 1 1 1 True True False False False

Additional files