Gene name: RPB4
Reference locus (S288C): YJL140W
Gene biotype: protein_coding
Description: RNA polymerase II subunit B32; forms dissociable heterodimer with Rpb7p; Rpb4/7 dissociates from RNAPII as Ser2 CTD phosphorylation increases; Rpb4/7 regulates cellular lifespan via mRNA decay process; involved in recruitment of 3'-end processing factors to transcribing RNAPII complex, export of mRNA to cytoplasm under stress conditions; also involved in translation initiation
Top 10 interactors (score): RPB9 (0.999); SPT5 (0.999); RPO26 (0.999); RPB3 (0.999); RTR1 (0.999); ELF1 (0.999); FCP1 (0.999); SPT4 (0.999); DST1 (0.999); RPB10 (0.999); RPO21 (0.999); RPC10 (0.999); RPB8 (0.999); RPB2 (0.999); TFG2 (0.999); RPB7 (0.999); RPB11 (0.999); TFG1 (0.999); RPB5 (0.999); SUA7 (0.998)
Homologues (species, bitscore): POLR2D (Homo sapiens, 68.6); Polr2d (Mus musculus, 68.6); polr2d (Danio rerio, 69.3); polr2d (Xenopus tropicalis, 69.7); Rpb4 (Drosophila melanogaster, 61.6); rpb-4 (Caenorhabditis elegans, 73.2); NRPB4 (Arabidopsis thaliana, 51.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:139257-139922:+ | gene-YJL140W_AKU4011 | rna-NM_001181573.1_AKU4011 | cds-NP_012395.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:473800-474465:- | gene-YJL140W_BG1 | rna-NM_001181573.1_BG1 | cds-NP_012395.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:151091-151756:+ | gene-YJL140W_Bruggeman | rna-NM_001181573.1_Bruggeman | cds-NP_012395.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:154879-155544:+ | gene-YJL140W_CAT1 | rna-NM_001181573.1_CAT1 | cds-NP_012395.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:144891-145556:+ | gene-YJL140W_CBS1585 | rna-NM_001181573.1_CBS1585 | cds-NP_012395.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:169640-170305:+ | gene-YJL140W_CBS436 | rna-NM_001181573.1_CBS436 | cds-NP_012395.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:141303-141968:+ | gene-YJL140W_CBS6412 | rna-NM_001181573.1_CBS6412 | cds-NP_012395.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:142367-143032:+ | gene-YJL140W_CBS6413 | rna-NM_001181573.1_CBS6413 | cds-NP_012395.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:133349-134014:+ | gene-YJL140W_CENPK1137D | rna-NM_001181573.1_CENPK1137D | cds-NP_012395.1_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:143415-144080:+ | gene-YJL140W_EthanolRed | rna-NM_001181573.1_EthanolRed | cds-NP_012395.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:148893-149558:+ | gene-YJL140W_FaliES1 | rna-NM_001181573.1_FaliES1 | cds-NP_012395.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000099.1:30071-30736:+ | gene-YJL140W_JAY291 | rna-NM_001181573.1_JAY291 | cds-NP_012395.1_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:153360-154025:+ | gene-YJL140W_MUCL30387 | rna-NM_001181573.1_MUCL30387 | cds-NP_012395.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:149412-150077:+ | gene-YJL140W_MUCL30388 | rna-NM_001181573.1_MUCL30388 | cds-NP_012395.1_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:143633-144298:+ | gene-YJL140W_MUCL39482 | rna-NM_001181573.1_MUCL39482 | cds-NP_012395.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:149151-149816:+ | gene-YJL140W_MUCL42920 | rna-NM_001181573.1_MUCL42920 | cds-NP_012395.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:150940-151605:+ | gene-YJL140W_NCIM3186 | rna-NM_001181573.1_NCIM3186 | cds-NP_012395.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:142245-142910:+ | gene-YJL140W_NCYC1407 | rna-NM_001181573.1_NCYC1407 | cds-NP_012395.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:155048-155713:+ | gene-YJL140W_PE2H3 | rna-NM_001181573.1_PE2H3 | cds-NP_012395.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:154691-155356:+ | gene-YJL140W_PE2H4 | rna-NM_001181573.1_PE2H4 | cds-NP_012395.1_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:150961-151626:+ | gene-YJL140W_S288C | rna-NM_001181573.1_S288C | cds-NP_012395.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000022.1:1988-2653:- | gene-YJL140W_SA1 | rna-NM_001181573.1_SA1 | cds-NP_012395.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:142084-142749:+ | gene-YJL140W_ThermosaccDry | rna-NM_001181573.1_ThermosaccDry | cds-NP_012395.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:149165-149830:+ | gene-YJL140W_VR1 | rna-NM_001181573.1_VR1 | cds-NP_012395.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:129373-130038:+ | gene-YJL140W_ZTW1 | rna-NM_001181573.1_ZTW1 | cds-NP_012395.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:154651-155316:+ | gene-YJL140W_Sparadoxus | rna-NM_001181573.1_Sparadoxus | cds-NP_012395.1_Sparadoxus | 93.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |