Gene name: ROM1
Reference locus (S288C): YGR070W
Gene biotype: protein_coding
Description: Guanine nucleotide exchange factor (GEF) for Rho1p; mutations are synthetically lethal with mutations in rom2, which also encodes a GEP; ROM1 has a paralog, ROM2, that arose from the whole genome duplication
Top 10 interactors (score): RHO1 (0.998); SLG1 (0.977); MID2 (0.964); TUS1 (0.951); MTL1 (0.941); WSC3 (0.937); RHO2 (0.928); WSC2 (0.922); ROM2 (0.895); RHO3 (0.874); RHO5 (0.873); RHO4 (0.873); PKC1 (0.872); LRG1 (0.852); MKK1 (0.828); BEM2 (0.821); BCK1 (0.811); SLT2 (0.805); FKS1 (0.757); MKK2 (0.735)
Homologues (species, bitscore): ARHGEF1 (Homo sapiens, 77.4); Net1 (Mus musculus, 78.6); arhgef12a (Danio rerio, 76.3); arhgef12 (Xenopus tropicalis, 75.9); RhoGEF4 (Drosophila melanogaster, 65.9); tag-52 (Caenorhabditis elegans, 56.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:611499-614966:+ | gene-YGR070W_AKU4011 | rna-NM_001181199.2_AKU4011 | cds-NP_011584.2_AKU4011 | 98.9 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000173.1:47766-51233:+ | gene-YGR070W_BG1 | rna-NM_001181199.2_BG1 | cds-NP_011584.2_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:613773-617240:+ | gene-YGR070W_Bruggeman | rna-NM_001181199.2_Bruggeman | cds-NP_011584.2_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:612205-615672:+ | gene-YGR070W_CAT1 | rna-NM_001181199.2_CAT1 | cds-NP_011584.2_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:612793-616260:+ | gene-YGR070W_CBS1585 | rna-NM_001181199.2_CBS1585 | cds-NP_011584.2_CBS1585 | 98.9 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:614103-617570:+ | gene-YGR070W_CBS436 | rna-NM_001181199.2_CBS436 | cds-NP_011584.2_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:605618-609085:+ | gene-YGR070W_CBS6412 | rna-NM_001181199.2_CBS6412 | cds-NP_011584.2_CBS6412 | 98.9 | 99.9 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:609501-612968:+ | gene-YGR070W_CBS6413 | rna-NM_001181199.2_CBS6413 | cds-NP_011584.2_CBS6413 | 98.9 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:627512-630979:+ | gene-YGR070W_CENPK1137D | rna-NM_001181199.2_CENPK1137D | cds-NP_011584.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:599752-603219:+ | gene-YGR070W_EthanolRed | rna-NM_001181199.2_EthanolRed | cds-NP_011584.2_EthanolRed | 98.9 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:603219-606686:+ | gene-YGR070W_FaliES1 | rna-NM_001181199.2_FaliES1 | cds-NP_011584.2_FaliES1 | 98.9 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000435.1:54153-57620:+ | gene-YGR070W_JAY291 | rna-NM_001181199.2_JAY291 | cds-NP_011584.2_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:610433-613900:+ | gene-YGR070W_MUCL30387 | rna-NM_001181199.2_MUCL30387 | cds-NP_011584.2_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:613803-617270:+ | gene-YGR070W_MUCL30388 | rna-NM_001181199.2_MUCL30388 | cds-NP_011584.2_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:608644-612111:+ | gene-YGR070W_MUCL39482 | rna-NM_001181199.2_MUCL39482 | cds-NP_011584.2_MUCL39482 | 98.9 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:618434-621901:+ | gene-YGR070W_MUCL42920 | rna-NM_001181199.2_MUCL42920 | cds-NP_011584.2_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:627806-631273:+ | gene-YGR070W_NCIM3186 | rna-NM_001181199.2_NCIM3186 | cds-NP_011584.2_NCIM3186 | 97.7 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:602825-606292:+ | gene-YGR070W_NCYC1407 | rna-NM_001181199.2_NCYC1407 | cds-NP_011584.2_NCYC1407 | 98.9 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:606058-609525:+ | gene-YGR070W_PE2H3 | rna-NM_001181199.2_PE2H3 | cds-NP_011584.2_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:611182-614649:+ | gene-YGR070W_PE2H4 | rna-NM_001181199.2_PE2H4 | cds-NP_011584.2_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:627806-631273:+ | gene-YGR070W_S288C | rna-NM_001181199.2_S288C | cds-NP_011584.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000015.1:54348-57815:+ | gene-YGR070W_SA1 | rna-NM_001181199.2_SA1 | cds-NP_011584.2_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:622545-626012:+ | gene-YGR070W_ThermosaccDry | rna-NM_001181199.2_ThermosaccDry | cds-NP_011584.2_ThermosaccDry | 98.9 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:719503-722970:+ | gene-YGR070W_VR1 | rna-NM_001181199.2_VR1 | cds-NP_011584.2_VR1 | 99.3 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000015.1:78015-81482:+ | gene-YGR070W_ZTW1 | rna-NM_001181199.2_ZTW1 | cds-NP_011584.2_ZTW1 | 98.9 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:613124-616591:+ | gene-YGR070W_Sparadoxus | rna-NM_001181199.2_Sparadoxus | cds-NP_011584.2_Sparadoxus | 88.4 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |