Gene name: ROK1
Reference locus (S288C): YGL171W
Gene biotype: protein_coding
Description: ATP-dependent RNA helicase ROK1; RNA-dependent ATPase; involved in pre-rRNA processing at sites A0, A1, and A2, and in control of cell cycle progression; contains two upstream open reading frames (uORFs) in 5' untranslated region which regulate translation; Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily
Top 10 interactors (score): PNO1 (0.999); PRP43 (0.999); MRD1 (0.999); UTP15 (0.999); PWP2 (0.999); MTR4 (0.999); ERB1 (0.999); UTP30 (0.999); NOP7 (0.999); ENP2 (0.999); UTP13 (0.999); NOP58 (0.999); KRI1 (0.999); IMP4 (0.999); UTP21 (0.999); UTP7 (0.999); NOP14 (0.999); DBP8 (0.999); RRP12 (0.999); TSR1 (0.999)
Homologues (species, bitscore): DDX52 (Homo sapiens, 402.9); Ddx52 (Mus musculus, 408.3); ddx42 (Danio rerio, 228.4); ddx52 (Xenopus tropicalis, 353.2); CG5589 (Drosophila melanogaster, 378.3); R05D11.4 (Caenorhabditis elegans, 284.3); AT3G09720 (Arabidopsis thaliana, 393.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:184964-186658:+ | gene-YGL171W_AKU4011 | rna-NM_001181036.1_AKU4011 | cds-NP_011344.1_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000132.1:223704-225398:- | gene-YGL171W_BG1 | rna-NM_001181036.1_BG1 | cds-NP_011344.1_BG1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:187157-188851:+ | gene-YGL171W_Bruggeman | rna-NM_001181036.1_Bruggeman | cds-NP_011344.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:183027-184721:+ | gene-YGL171W_CAT1 | rna-NM_001181036.1_CAT1 | cds-NP_011344.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:188103-189797:+ | gene-YGL171W_CBS1585 | rna-NM_001181036.1_CBS1585 | cds-NP_011344.1_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:183017-184711:+ | gene-YGL171W_CBS436 | rna-NM_001181036.1_CBS436 | cds-NP_011344.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:174566-176260:+ | gene-YGL171W_CBS6412 | rna-NM_001181036.1_CBS6412 | cds-NP_011344.1_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:182415-184109:+ | gene-YGL171W_CBS6413 | rna-NM_001181036.1_CBS6413 | cds-NP_011344.1_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:182617-184311:+ | gene-YGL171W_CENPK1137D | rna-NM_001181036.1_CENPK1137D | cds-NP_011344.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:174771-176465:+ | gene-YGL171W_EthanolRed | rna-NM_001181036.1_EthanolRed | cds-NP_011344.1_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:176017-177711:+ | gene-YGL171W_FaliES1 | rna-NM_001181036.1_FaliES1 | cds-NP_011344.1_FaliES1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000090.1:26248-27942:+ | gene-YGL171W_JAY291 | rna-NM_001181036.1_JAY291 | cds-NP_011344.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:184405-186099:+ | gene-YGL171W_MUCL30387 | rna-NM_001181036.1_MUCL30387 | cds-NP_011344.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:187495-189189:+ | gene-YGL171W_MUCL30388 | rna-NM_001181036.1_MUCL30388 | cds-NP_011344.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:185127-186821:+ | gene-YGL171W_MUCL39482 | rna-NM_001181036.1_MUCL39482 | cds-NP_011344.1_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:187712-189406:+ | gene-YGL171W_MUCL42920 | rna-NM_001181036.1_MUCL42920 | cds-NP_011344.1_MUCL42920 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:182390-184084:+ | gene-YGL171W_NCIM3186 | rna-NM_001181036.1_NCIM3186 | cds-NP_011344.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:176591-178285:+ | gene-YGL171W_NCYC1407 | rna-NM_001181036.1_NCYC1407 | cds-NP_011344.1_NCYC1407 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:178548-180242:+ | gene-YGL171W_PE2H3 | rna-NM_001181036.1_PE2H3 | cds-NP_011344.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:178099-179793:+ | gene-YGL171W_PE2H4 | rna-NM_001181036.1_PE2H4 | cds-NP_011344.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:182390-184084:+ | gene-YGL171W_S288C | rna-NM_001181036.1_S288C | cds-NP_011344.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000067.1:42209-43903:+ | gene-YGL171W_SA1 | rna-NM_001181036.1_SA1 | cds-NP_011344.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:176246-177940:+ | gene-YGL171W_ThermosaccDry | rna-NM_001181036.1_ThermosaccDry | cds-NP_011344.1_ThermosaccDry | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:183453-185147:+ | gene-YGL171W_VR1 | rna-NM_001181036.1_VR1 | cds-NP_011344.1_VR1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:174697-176391:+ | gene-YGL171W_ZTW1 | rna-NM_001181036.1_ZTW1 | cds-NP_011344.1_ZTW1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:181515-183212:+ | gene-YGL171W_Sparadoxus | rna-NM_001181036.1_Sparadoxus | cds-NP_011344.1_Sparadoxus | 90.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |