Gene name: ROG3
Reference locus (S288C): YFR022W
Gene biotype: protein_coding
Description: Arrestin-related trafficking adapter 4/5/7; Protein ROG3; Alpha-arrestin involved in ubiquitin-dependent endocytosis; contributes to desensitization of agonist-occupied alpha-factor receptor Ste2p by Rsp5p-independent internalization; PPXY motif-mediated binding of the ubiquitin ligase Rsp5p is not required for adaptation; mutation suppresses the temperature sensitivity of an mck1 rim11 double mutant; SWAT-GFP and mCherry fusion proteins localize to the cytosol; ROG3 has a paralog, ROD1, that arose from the whole genome duplication
Top 10 interactors (score): RSP5 (0.994); LDB19 (0.938); CSR2 (0.846); STE2 (0.838); ECM21 (0.813); ART10 (0.809); RIM8 (0.774); BUL2 (0.712); SPO23 (0.711); BUL1 (0.693); DCR2 (0.675); YNR068C (0.65); RHO1 (0.624); SST2 (0.616); SNF1 (0.587); BSC5 (0.569); RAS2 (0.547); YCK2 (0.534); JEN1 (0.53); SVL3 (0.499)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005300.1:187070-189271:+ | gene-YFR022W_AKU4011 | rna-NM_001179987.3_AKU4011 | cds-NP_116677.3_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000071.1:71424-73625:- | gene-YFR022W_BG1 | rna-NM_001179987.3_BG1 | cds-NP_116677.3_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005508.1:189163-191364:+ | gene-YFR022W_Bruggeman | rna-NM_001179987.3_Bruggeman | cds-NP_116677.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005524.1:192436-194609:+ | gene-YFR022W_CAT1 | rna-NM_001179987.3_CAT1 | cds-NP_116677.3_CAT1 | 98.0 | 98.7 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005364.1:188561-190762:+ | gene-YFR022W_CBS1585 | rna-NM_001179987.3_CBS1585 | cds-NP_116677.3_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005348.1:161760-163961:+ | gene-YFR022W_CBS436 | rna-NM_001179987.3_CBS436 | cds-NP_116677.3_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005332.1:187642-189843:+ | gene-YFR022W_CBS6412 | rna-NM_001179987.3_CBS6412 | cds-NP_116677.3_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005316.1:190296-192497:+ | gene-YFR022W_CBS6413 | rna-NM_001179987.3_CBS6413 | cds-NP_116677.3_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001527.1:192904-195105:+ | gene-YFR022W_CENPK1137D | rna-NM_001179987.3_CENPK1137D | cds-NP_116677.3_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005476.1:186177-188378:+ | gene-YFR022W_EthanolRed | rna-NM_001179987.3_EthanolRed | cds-NP_116677.3_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005540.1:187827-190028:+ | gene-YFR022W_FaliES1 | rna-NM_001179987.3_FaliES1 | cds-NP_116677.3_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000452.1:34553-36754:+ | gene-YFR022W_JAY291 | rna-NM_001179987.3_JAY291 | cds-NP_116677.3_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005412.1:190389-192590:+ | gene-YFR022W_MUCL30387 | rna-NM_001179987.3_MUCL30387 | cds-NP_116677.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005444.1:186646-188847:+ | gene-YFR022W_MUCL30388 | rna-NM_001179987.3_MUCL30388 | cds-NP_116677.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005284.1:186479-188680:+ | gene-YFR022W_MUCL39482 | rna-NM_001179987.3_MUCL39482 | cds-NP_116677.3_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005428.1:185757-187958:+ | gene-YFR022W_MUCL42920 | rna-NM_001179987.3_MUCL42920 | cds-NP_116677.3_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011815.1:196832-199033:+ | gene-YFR022W_NCIM3186 | rna-NM_001179987.3_NCIM3186 | cds-NP_116677.3_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005268.1:187361-189562:+ | gene-YFR022W_NCYC1407 | rna-NM_001179987.3_NCYC1407 | cds-NP_116677.3_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994145.1:229767-231968:+ | gene-YFR022W_PE2H3 | rna-NM_001179987.3_PE2H3 | cds-NP_116677.3_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999877.1:229315-231516:+ | gene-YFR022W_PE2H4 | rna-NM_001179987.3_PE2H4 | cds-NP_116677.3_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001138.5:196833-199034:+ | gene-YFR022W_S288C | rna-NM_001179987.3_S288C | cds-NP_116677.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000011.1:125372-127573:- | gene-YFR022W_SA1 | rna-NM_001179987.3_SA1 | cds-NP_116677.3_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005492.1:186984-189185:+ | gene-YFR022W_ThermosaccDry | rna-NM_001179987.3_ThermosaccDry | cds-NP_116677.3_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005460.1:202998-205199:+ | gene-YFR022W_VR1 | rna-NM_001179987.3_VR1 | cds-NP_116677.3_VR1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000013.1:117458-119659:+ | gene-YFR022W_ZTW1 | rna-NM_001179987.3_ZTW1 | cds-NP_116677.3_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047492.1:210991-213186:+ | gene-YFR022W_Sparadoxus | rna-NM_001179987.3_Sparadoxus | cds-NP_116677.3_Sparadoxus | 90.0 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |