RNY1 (YPL123C)


Gene profile

Gene name: RNY1
Reference locus (S288C): YPL123C
Gene biotype: protein_coding

Description: Ribonuclease T2-like; Vacuolar RNase of the T(2) family; relocalizes to the cytosol where it cleaves tRNAs upon oxidative or stationary phase stress; required for tRNA-specific translational pausing suring oxidative stress; promotes apoptosis under stress conditions and this function is independent of Rny1p catalytic activity

Top 10 interactors (score): YBR056W (0.857); DCS2 (0.857); TFS1 (0.835); SOL4 (0.812); UIP4 (0.811); GAD1 (0.804); YLR345W (0.787); YKL091C (0.772); DCS1 (0.769); RAT1 (0.758); NNR1 (0.735); SYM1 (0.733); GGA1 (0.732); VPS68 (0.728); STF2 (0.721); YHI9 (0.715); YJL120W (0.71); YBR139W (0.684); XRN1 (0.672); YJL144W (0.664)

Homologues (species, bitscore): RNASET2 (Homo sapiens, 57.4); Rnaset2a (Mus musculus, 59.7); rnaset2 (Xenopus tropicalis, 55.1); RNS1 (Arabidopsis thaliana, 61.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:295282-296586:- gene-YPL123C_AKU4011 rna-NM_001183937.1_AKU4011 cds-NP_015202.1_AKU4011 99.0 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000069.1:501039-502343:- gene-YPL123C_BG1 rna-NM_001183937.1_BG1 cds-NP_015202.1_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:321286-322590:- gene-YPL123C_Bruggeman rna-NM_001183937.1_Bruggeman cds-NP_015202.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:317954-319258:- gene-YPL123C_CAT1 rna-NM_001183937.1_CAT1 cds-NP_015202.1_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:299355-300659:- gene-YPL123C_CBS1585 rna-NM_001183937.1_CBS1585 cds-NP_015202.1_CBS1585 99.0 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:314029-315333:- gene-YPL123C_CBS436 rna-NM_001183937.1_CBS436 cds-NP_015202.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:304024-305328:- gene-YPL123C_CBS6412 rna-NM_001183937.1_CBS6412 cds-NP_015202.1_CBS6412 99.0 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:295991-297295:- gene-YPL123C_CBS6413 rna-NM_001183937.1_CBS6413 cds-NP_015202.1_CBS6413 99.1 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:317574-318878:- gene-YPL123C_CENPK1137D rna-NM_001183937.1_CENPK1137D cds-NP_015202.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:293971-295275:- gene-YPL123C_EthanolRed rna-NM_001183937.1_EthanolRed cds-NP_015202.1_EthanolRed 99.1 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:301563-302867:- gene-YPL123C_FaliES1 rna-NM_001183937.1_FaliES1 cds-NP_015202.1_FaliES1 99.1 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000007.1:62950-64254:+ gene-YPL123C_JAY291 rna-NM_001183937.1_JAY291 cds-NP_015202.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:312525-313829:- gene-YPL123C_MUCL30387 rna-NM_001183937.1_MUCL30387 cds-NP_015202.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:310546-311850:- gene-YPL123C_MUCL30388 rna-NM_001183937.1_MUCL30388 cds-NP_015202.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:292684-293988:- gene-YPL123C_MUCL39482 rna-NM_001183937.1_MUCL39482 cds-NP_015202.1_MUCL39482 99.0 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:349927-351231:- gene-YPL123C_MUCL42920 rna-NM_001183937.1_MUCL42920 cds-NP_015202.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:317624-318928:- gene-YPL123C_NCIM3186 rna-NM_001183937.1_NCIM3186 cds-NP_015202.1_NCIM3186 98.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:299137-300441:- gene-YPL123C_NCYC1407 rna-NM_001183937.1_NCYC1407 cds-NP_015202.1_NCYC1407 99.0 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:306628-307932:- gene-YPL123C_PE2H3 rna-NM_001183937.1_PE2H3 cds-NP_015202.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:306251-307555:- gene-YPL123C_PE2H4 rna-NM_001183937.1_PE2H4 cds-NP_015202.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:317641-318945:- gene-YPL123C_S288C rna-NM_001183937.1_S288C cds-NP_015202.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000012.1:54735-56039:+ gene-YPL123C_SA1 rna-NM_001183937.1_SA1 cds-NP_015202.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:301361-302665:- gene-YPL123C_ThermosaccDry rna-NM_001183937.1_ThermosaccDry cds-NP_015202.1_ThermosaccDry 99.1 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:316340-317644:- gene-YPL123C_VR1 rna-NM_001183937.1_VR1 cds-NP_015202.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:300686-301990:- gene-YPL123C_ZTW1 rna-NM_001183937.1_ZTW1 cds-NP_015202.1_ZTW1 99.1 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:302422-303726:- gene-YPL123C_Sparadoxus rna-NM_001183937.1_Sparadoxus cds-NP_015202.1_Sparadoxus 88.6 99.9 Verified 1 1 1 False True False False False

Additional files