Gene name: RNR3
Reference locus (S288C): YIL066C
Gene biotype: protein_coding
Description: Ribonucleoside-diphosphate reductase large chain 2; Minor isoform of large subunit of ribonucleotide-diphosphate reductase; the RNR complex catalyzes rate-limiting step in dNTP synthesis, regulated by DNA replication and DNA damage checkpoint pathways via localization of small subunits; RNR3 has a paralog, RNR1, that arose from the whole genome duplication
Top 10 interactors (score): RNR4 (0.999); RNR2 (0.999); RNR1 (0.989); MCM5 (0.987); MCM7 (0.984); CDC8 (0.972); POL1 (0.964); DUT1 (0.963); CDC21 (0.963); POL30 (0.962); MCM4 (0.962); CDC6 (0.961); POL2 (0.96); PRI2 (0.956); MCM2 (0.952); PRI1 (0.95); YNK1 (0.946); RFA1 (0.944); POL12 (0.942); GUK1 (0.938)
Homologues (species, bitscore): RRM1 (Homo sapiens, 1122.1); Rrm1 (Mus musculus, 1121.7); rrm1 (Danio rerio, 1128.6); rrm1 (Xenopus tropicalis, 1115.9); RnrL (Drosophila melanogaster, 1070.5); rnr-1 (Caenorhabditis elegans, 1117.8); RNR1 (Arabidopsis thaliana, 1082.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:234769-237378:- | gene-YIL066C_AKU4011 | rna-NM_001179416.3_AKU4011 | cds-NP_012198.3_AKU4011 | 98.8 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000164.1:96701-99310:- | gene-YIL066C_BG1 | rna-NM_001179416.3_BG1 | cds-NP_012198.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:240184-242793:- | gene-YIL066C_Bruggeman | rna-NM_001179416.3_Bruggeman | cds-NP_012198.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:230463-233072:- | gene-YIL066C_CAT1 | rna-NM_001179416.3_CAT1 | cds-NP_012198.3_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:234340-236949:- | gene-YIL066C_CBS1585 | rna-NM_001179416.3_CBS1585 | cds-NP_012198.3_CBS1585 | 98.8 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:230390-232999:- | gene-YIL066C_CBS436 | rna-NM_001179416.3_CBS436 | cds-NP_012198.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:231717-234326:- | gene-YIL066C_CBS6412 | rna-NM_001179416.3_CBS6412 | cds-NP_012198.3_CBS6412 | 98.7 | 99.9 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:226260-228869:- | gene-YIL066C_CBS6413 | rna-NM_001179416.3_CBS6413 | cds-NP_012198.3_CBS6413 | 98.8 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:229802-232411:- | gene-YIL066C_CENPK1137D | rna-NM_001179416.3_CENPK1137D | cds-NP_012198.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:219064-221673:- | gene-YIL066C_EthanolRed | rna-NM_001179416.3_EthanolRed | cds-NP_012198.3_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:235973-238582:- | gene-YIL066C_FaliES1 | rna-NM_001179416.3_FaliES1 | cds-NP_012198.3_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000365.1:59551-62160:+ | gene-YIL066C_JAY291 | rna-NM_001179416.3_JAY291 | cds-NP_012198.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:238403-241012:- | gene-YIL066C_MUCL30387 | rna-NM_001179416.3_MUCL30387 | cds-NP_012198.3_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:235012-237621:- | gene-YIL066C_MUCL30388 | rna-NM_001179416.3_MUCL30388 | cds-NP_012198.3_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:235187-237796:- | gene-YIL066C_MUCL39482 | rna-NM_001179416.3_MUCL39482 | cds-NP_012198.3_MUCL39482 | 98.8 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:238551-241160:- | gene-YIL066C_MUCL42920 | rna-NM_001179416.3_MUCL42920 | cds-NP_012198.3_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:238099-240708:- | gene-YIL066C_NCIM3186 | rna-NM_001179416.3_NCIM3186 | cds-NP_012198.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:239464-242073:- | gene-YIL066C_NCYC1407 | rna-NM_001179416.3_NCYC1407 | cds-NP_012198.3_NCYC1407 | 98.9 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:233445-236054:- | gene-YIL066C_PE2H3 | rna-NM_001179416.3_PE2H3 | cds-NP_012198.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:228160-230769:- | gene-YIL066C_PE2H4 | rna-NM_001179416.3_PE2H4 | cds-NP_012198.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:238099-240708:- | gene-YIL066C_S288C | rna-NM_001179416.3_S288C | cds-NP_012198.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000031.1:85125-87734:+ | gene-YIL066C_SA1 | rna-NM_001179416.3_SA1 | cds-NP_012198.3_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:234636-237245:- | gene-YIL066C_ThermosaccDry | rna-NM_001179416.3_ThermosaccDry | cds-NP_012198.3_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:232319-234928:- | gene-YIL066C_VR1 | rna-NM_001179416.3_VR1 | cds-NP_012198.3_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:208897-211506:- | gene-YIL066C_ZTW1 | rna-NM_001179416.3_ZTW1 | cds-NP_012198.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:232997-235606:- | gene-YIL066C_Sparadoxus | rna-NM_001179416.3_Sparadoxus | cds-NP_012198.3_Sparadoxus | 91.2 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |