RNR2 (YJL026W)


Gene profile

Gene name: RNR2
Reference locus (S288C): YJL026W
Gene biotype: protein_coding

Description: Ribonucleoside-diphosphate reductase small chain 1; Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits; RNR2 has a paralog, RNR4, that arose from the whole genome duplication; Belongs to the ribonucleoside diphosphate reductase small chain family

Top 10 interactors (score): RNR3 (0.999); RNR4 (0.999); RNR1 (0.999); WTM1 (0.986); DUN1 (0.978); ASF1 (0.968); MEC1 (0.967); CDC21 (0.958); CDC8 (0.952); MCM2 (0.949); HUG1 (0.947); MCM7 (0.943); RAD53 (0.941); RFA2 (0.941); POL30 (0.939); PRI1 (0.936); DUT1 (0.934); POL1 (0.921); MCM5 (0.92); MAD2 (0.919)

Homologues (species, bitscore): RRM2 (Homo sapiens, 473.8); Rrm2 (Mus musculus, 474.9); rrm2 (Danio rerio, 481.1); rrm2.1 (Xenopus tropicalis, 474.9); RnrS (Drosophila melanogaster, 448.7); rnr-2 (Caenorhabditis elegans, 421.8); TSO2 (Arabidopsis thaliana, 433.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005304.1:375360-376559:+ gene-YJL026W_AKU4011 rna-NM_001181460.1_AKU4011 cds-NP_012508.1_AKU4011 99.6 100.0 Mismatch 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000190.1:237526-238725:- gene-YJL026W_BG1 rna-NM_001181460.1_BG1 cds-NP_012508.1_BG1 99.5 100.0 Mismatch 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005512.1:389553-390752:+ gene-YJL026W_Bruggeman rna-NM_001181460.1_Bruggeman cds-NP_012508.1_Bruggeman 99.5 100.0 Mismatch 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005528.1:393510-394709:+ gene-YJL026W_CAT1 rna-NM_001181460.1_CAT1 cds-NP_012508.1_CAT1 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005368.1:387025-388224:+ gene-YJL026W_CBS1585 rna-NM_001181460.1_CBS1585 cds-NP_012508.1_CBS1585 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005352.1:405381-406580:+ gene-YJL026W_CBS436 rna-NM_001181460.1_CBS436 cds-NP_012508.1_CBS436 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005336.1:375621-376820:+ gene-YJL026W_CBS6412 rna-NM_001181460.1_CBS6412 cds-NP_012508.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005320.1:377502-378701:+ gene-YJL026W_CBS6413 rna-NM_001181460.1_CBS6413 cds-NP_012508.1_CBS6413 99.6 100.0 Mismatch 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001531.1:374830-376029:+ gene-YJL026W_CENPK1137D rna-NM_001181460.1_CENPK1137D cds-NP_012508.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005480.1:378577-379776:+ gene-YJL026W_EthanolRed rna-NM_001181460.1_EthanolRed cds-NP_012508.1_EthanolRed 99.7 100.0 Mismatch 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005544.1:391024-392223:+ gene-YJL026W_FaliES1 rna-NM_001181460.1_FaliES1 cds-NP_012508.1_FaliES1 99.5 100.0 Mismatch 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000200.1:23207-24406:- gene-YJL026W_JAY291 rna-NM_001181460.1_JAY291 cds-NP_012508.1_JAY291 99.5 100.0 Mismatch 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005416.1:389794-390993:+ gene-YJL026W_MUCL30387 rna-NM_001181460.1_MUCL30387 cds-NP_012508.1_MUCL30387 99.5 100.0 Mismatch 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005448.1:385938-387137:+ gene-YJL026W_MUCL30388 rna-NM_001181460.1_MUCL30388 cds-NP_012508.1_MUCL30388 99.6 100.0 Mismatch 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005288.1:380349-381548:+ gene-YJL026W_MUCL39482 rna-NM_001181460.1_MUCL39482 cds-NP_012508.1_MUCL39482 99.6 100.0 Mismatch 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005432.1:385681-386880:+ gene-YJL026W_MUCL42920 rna-NM_001181460.1_MUCL42920 cds-NP_012508.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011819.1:392383-393582:+ gene-YJL026W_NCIM3186 rna-NM_001181460.1_NCIM3186 cds-NP_012508.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005272.1:378297-379496:+ gene-YJL026W_NCYC1407 rna-NM_001181460.1_NCYC1407 cds-NP_012508.1_NCYC1407 99.6 100.0 Mismatch 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994149.1:390371-391570:+ gene-YJL026W_PE2H3 rna-NM_001181460.1_PE2H3 cds-NP_012508.1_PE2H3 99.5 100.0 Mismatch 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999881.1:390017-391216:+ gene-YJL026W_PE2H4 rna-NM_001181460.1_PE2H4 cds-NP_012508.1_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001142.9:392404-393603:+ gene-YJL026W_S288C rna-NM_001181460.1_S288C cds-NP_012508.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000003.1:187902-189101:+ gene-YJL026W_SA1 rna-NM_001181460.1_SA1 cds-NP_012508.1_SA1 99.5 100.0 Mismatch 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005496.1:384685-385884:+ gene-YJL026W_ThermosaccDry rna-NM_001181460.1_ThermosaccDry cds-NP_012508.1_ThermosaccDry 99.7 100.0 Mismatch 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005464.1:386529-387728:+ gene-YJL026W_VR1 rna-NM_001181460.1_VR1 cds-NP_012508.1_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000021.1:365350-366549:+ gene-YJL026W_ZTW1 rna-NM_001181460.1_ZTW1 cds-NP_012508.1_ZTW1 99.6 100.0 Mismatch 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047496.1:390598-391797:+ gene-YJL026W_Sparadoxus rna-NM_001181460.1_Sparadoxus cds-NP_012508.1_Sparadoxus 95.5 100.0 Verified 1 1 1 False True False False False

Additional files