Gene name: RNA14
Reference locus (S288C): YMR061W
Gene biotype: protein_coding
Description: mRNA 3'-end-processing protein RNA14; Component of the cleavage and polyadenylation factor I (CF I); CF 1, composed of the CF 1A complex (Rna14p, Rna15p, Clp1p, Pcf11p) and Hrp1, is involved in cleavage and polyadenylation of mRNA 3' ends; bridges interaction between Rna15p and Hrp1p in the CF I complex; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay; required for gene looping and maintenance of genome stability; relocalizes to the cytosol in response to hypoxia
Top 10 interactors (score): YSH1 (0.999); CLP1 (0.999); CFT2 (0.999); RNA15 (0.999); PAP1 (0.999); PTA1 (0.999); REF2 (0.999); YTH1 (0.999); PCF11 (0.999); FIP1 (0.999); CFT1 (0.999); PFS2 (0.998); PTI1 (0.996); MPE1 (0.994); SSU72 (0.994); SYC1 (0.991); HRP1 (0.991); SWD2 (0.981); GLC7 (0.944); RPO21 (0.918)
Homologues (species, bitscore): CSTF3 (Homo sapiens, 211.8); Cstf3 (Mus musculus, 213.0); cstf3 (Danio rerio, 214.5); cstf3 (Xenopus tropicalis, 121.7); Su(f) (Drosophila melanogaster, 184.5); suf-1 (Caenorhabditis elegans, 187.2); CSTF77 (Arabidopsis thaliana, 164.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:430468-432501:+ | gene-YMR061W_AKU4011 | rna-NM_001182559.1_AKU4011 | cds-NP_013777.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:110282-112315:- | gene-YMR061W_BG1 | rna-NM_001182559.1_BG1 | cds-NP_013777.1_BG1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:372635-374668:+ | gene-YMR061W_Bruggeman | rna-NM_001182559.1_Bruggeman | cds-NP_013777.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:372974-375007:+ | gene-YMR061W_CAT1 | rna-NM_001182559.1_CAT1 | cds-NP_013777.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:363411-365444:+ | gene-YMR061W_CBS1585 | rna-NM_001182559.1_CBS1585 | cds-NP_013777.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:368967-371000:+ | gene-YMR061W_CBS436 | rna-NM_001182559.1_CBS436 | cds-NP_013777.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:476811-478844:+ | gene-YMR061W_CBS6412 | rna-NM_001182559.1_CBS6412 | cds-NP_013777.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:362668-364701:+ | gene-YMR061W_CBS6413 | rna-NM_001182559.1_CBS6413 | cds-NP_013777.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:386869-388902:+ | gene-YMR061W_CENPK1137D | rna-NM_001182559.1_CENPK1137D | cds-NP_013777.1_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:363263-365296:+ | gene-YMR061W_EthanolRed | rna-NM_001182559.1_EthanolRed | cds-NP_013777.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:366432-368465:+ | gene-YMR061W_FaliES1 | rna-NM_001182559.1_FaliES1 | cds-NP_013777.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000033.1:68478-70511:- | gene-YMR061W_JAY291 | rna-NM_001182559.1_JAY291 | cds-NP_013777.1_JAY291 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:368377-370410:+ | gene-YMR061W_MUCL30387 | rna-NM_001182559.1_MUCL30387 | cds-NP_013777.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:373046-375079:+ | gene-YMR061W_MUCL30388 | rna-NM_001182559.1_MUCL30388 | cds-NP_013777.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:363699-365732:+ | gene-YMR061W_MUCL39482 | rna-NM_001182559.1_MUCL39482 | cds-NP_013777.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:370357-372390:+ | gene-YMR061W_MUCL42920 | rna-NM_001182559.1_MUCL42920 | cds-NP_013777.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:392709-394742:+ | gene-YMR061W_NCIM3186 | rna-NM_001182559.1_NCIM3186 | cds-NP_013777.1_NCIM3186 | 96.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:363611-365644:+ | gene-YMR061W_NCYC1407 | rna-NM_001182559.1_NCYC1407 | cds-NP_013777.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:369564-371597:+ | gene-YMR061W_PE2H3 | rna-NM_001182559.1_PE2H3 | cds-NP_013777.1_PE2H3 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:375659-377692:+ | gene-YMR061W_PE2H4 | rna-NM_001182559.1_PE2H4 | cds-NP_013777.1_PE2H4 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:392755-394788:+ | gene-YMR061W_S288C | rna-NM_001182559.1_S288C | cds-NP_013777.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:155358-157391:- | gene-YMR061W_SA1 | rna-NM_001182559.1_SA1 | cds-NP_013777.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:364235-366268:+ | gene-YMR061W_ThermosaccDry | rna-NM_001182559.1_ThermosaccDry | cds-NP_013777.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:375130-377163:+ | gene-YMR061W_VR1 | rna-NM_001182559.1_VR1 | cds-NP_013777.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:342515-344548:+ | gene-YMR061W_ZTW1 | rna-NM_001182559.1_ZTW1 | cds-NP_013777.1_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:376112-378145:+ | gene-YMR061W_Sparadoxus | rna-NM_001182559.1_Sparadoxus | cds-NP_013777.1_Sparadoxus | 92.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |