Gene name: RMD5
Reference locus (S288C): YDR255C
Gene biotype: protein_coding
Description: E3 ubiquitin-protein transferase RMND5; Sporulation protein RMD5; Component of GID Complex that confers ubiquitin ligase (U3) activity; necessary for polyubiquitination and degradation of the gluconeogenic enzyme fructose-1,6-bisphosphatase; forms dimer with Fyv10p that is then recruited to GID Complex by Gid8p; also required for sporulation; conserved protein that has a degenerate RING finger domain
Top 10 interactors (score): GID7 (0.999); VID30 (0.999); VID28 (0.999); GID8 (0.999); FYV10 (0.999); VID24 (0.998); YGR066C (0.886); UBC8 (0.877); MOH1 (0.794); YDL176W (0.695); EAR1 (0.693); SSH4 (0.693); FBP1 (0.685); UBP14 (0.614); RDL2 (0.567); GYL1 (0.564); GYP5 (0.564); MDH2 (0.56); RFU1 (0.559); KAP95 (0.538)
Homologues (species, bitscore): RMND5A (Homo sapiens, 108.6); Rmnd5a (Mus musculus, 108.6); rmnd5b (Danio rerio, 105.1); rmnd5a (Xenopus tropicalis, 100.1); CG3295 (Drosophila melanogaster, 105.5); T07D1.2 (Caenorhabditis elegans, 71.6); AT4G37880 (Arabidopsis thaliana, 113.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:922915-924180:- | gene-YDR255C_AKU4011 | rna-NM_001180563.3_AKU4011 | cds-NP_010541.3_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:201087-202352:+ | gene-YDR255C_BG1 | rna-NM_001180563.3_BG1 | cds-NP_010541.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:955244-956509:- | gene-YDR255C_Bruggeman | rna-NM_001180563.3_Bruggeman | cds-NP_010541.3_Bruggeman | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:942528-943793:- | gene-YDR255C_CAT1 | rna-NM_001180563.3_CAT1 | cds-NP_010541.3_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:913264-914529:- | gene-YDR255C_CBS1585 | rna-NM_001180563.3_CBS1585 | cds-NP_010541.3_CBS1585 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:942793-944058:- | gene-YDR255C_CBS436 | rna-NM_001180563.3_CBS436 | cds-NP_010541.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:910024-911289:- | gene-YDR255C_CBS6412 | rna-NM_001180563.3_CBS6412 | cds-NP_010541.3_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:941118-942383:- | gene-YDR255C_CBS6413 | rna-NM_001180563.3_CBS6413 | cds-NP_010541.3_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:965480-966745:- | gene-YDR255C_CENPK1137D | rna-NM_001180563.3_CENPK1137D | cds-NP_010541.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:923583-924848:- | gene-YDR255C_EthanolRed | rna-NM_001180563.3_EthanolRed | cds-NP_010541.3_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:931785-933050:- | gene-YDR255C_FaliES1 | rna-NM_001180563.3_FaliES1 | cds-NP_010541.3_FaliES1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000261.1:20289-21554:- | gene-YDR255C_JAY291 | rna-NM_001180563.3_JAY291 | cds-NP_010541.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:941142-942407:- | gene-YDR255C_MUCL30387 | rna-NM_001180563.3_MUCL30387 | cds-NP_010541.3_MUCL30387 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:929172-930437:- | gene-YDR255C_MUCL30388 | rna-NM_001180563.3_MUCL30388 | cds-NP_010541.3_MUCL30388 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:914669-915934:- | gene-YDR255C_MUCL39482 | rna-NM_001180563.3_MUCL39482 | cds-NP_010541.3_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:854433-855698:- | gene-YDR255C_MUCL42920 | rna-NM_001180563.3_MUCL42920 | cds-NP_010541.3_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:966480-967745:- | gene-YDR255C_NCIM3186 | rna-NM_001180563.3_NCIM3186 | cds-NP_010541.3_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:918338-919603:- | gene-YDR255C_NCYC1407 | rna-NM_001180563.3_NCYC1407 | cds-NP_010541.3_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:934566-935831:- | gene-YDR255C_PE2H3 | rna-NM_001180563.3_PE2H3 | cds-NP_010541.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:939843-941108:- | gene-YDR255C_PE2H4 | rna-NM_001180563.3_PE2H4 | cds-NP_010541.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:966557-967822:- | gene-YDR255C_S288C | rna-NM_001180563.3_S288C | cds-NP_010541.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000013.1:172403-173668:- | gene-YDR255C_SA1 | rna-NM_001180563.3_SA1 | cds-NP_010541.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:929939-931204:- | gene-YDR255C_ThermosaccDry | rna-NM_001180563.3_ThermosaccDry | cds-NP_010541.3_ThermosaccDry | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:945166-946431:- | gene-YDR255C_VR1 | rna-NM_001180563.3_VR1 | cds-NP_010541.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000007.1:192683-193948:- | gene-YDR255C_ZTW1 | rna-NM_001180563.3_ZTW1 | cds-NP_010541.3_ZTW1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:935325-936590:- | gene-YDR255C_Sparadoxus | rna-NM_001180563.3_Sparadoxus | cds-NP_010541.3_Sparadoxus | 90.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |