RMA1 (YKL132C)


Gene profile

Gene name: RMA1
Reference locus (S288C): YKL132C
Gene biotype: protein_coding

Description: Probable folylpolyglutamate synthase; Putative dihydrofolate synthetase; similar to E. coli folylpolyglutamate synthetase/dihydrofolate synthetase; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; RMA1 has a paralog, FOL3, that arose from the whole genome duplication

Top 10 interactors (score): SHM1 (0.985); MIS1 (0.975); DFR1 (0.961); FOL3 (0.954); SHM2 (0.951); ADE3 (0.945); FOL1 (0.945); CDC21 (0.922); MET7 (0.899); FOL2 (0.888); MET12 (0.866); CAB5 (0.794); TRP3 (0.77); YBR013C (0.75); YMR103C (0.75); SLM2 (0.744); TRP5 (0.711); PMU1 (0.711); KTR4 (0.71); FAU1 (0.706)

Homologues (species, bitscore): fpgs (Xenopus tropicalis, 52.8); GLA1 (Arabidopsis thaliana, 79.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:180470-181762:- gene-YKL132C_AKU4011 rna-NM_001179698.1_AKU4011 cds-NP_012790.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000030.1:157634-158926:- gene-YKL132C_BG1 rna-NM_001179698.1_BG1 cds-NP_012790.1_BG1 99.1 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:198132-199424:- gene-YKL132C_Bruggeman rna-NM_001179698.1_Bruggeman cds-NP_012790.1_Bruggeman 99.3 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:193455-194747:- gene-YKL132C_CAT1 rna-NM_001179698.1_CAT1 cds-NP_012790.1_CAT1 99.3 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:192722-194014:- gene-YKL132C_CBS1585 rna-NM_001179698.1_CBS1585 cds-NP_012790.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:191312-192604:- gene-YKL132C_CBS436 rna-NM_001179698.1_CBS436 cds-NP_012790.1_CBS436 98.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:177344-178636:- gene-YKL132C_CBS6412 rna-NM_001179698.1_CBS6412 cds-NP_012790.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:193167-194459:- gene-YKL132C_CBS6413 rna-NM_001179698.1_CBS6413 cds-NP_012790.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:193218-194510:- gene-YKL132C_CENPK1137D rna-NM_001179698.1_CENPK1137D cds-NP_012790.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:191203-192495:- gene-YKL132C_EthanolRed rna-NM_001179698.1_EthanolRed cds-NP_012790.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:192015-193307:- gene-YKL132C_FaliES1 rna-NM_001179698.1_FaliES1 cds-NP_012790.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000357.1:14345-15637:- gene-YKL132C_JAY291 rna-NM_001179698.1_JAY291 cds-NP_012790.1_JAY291 99.1 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:200233-201525:- gene-YKL132C_MUCL30387 rna-NM_001179698.1_MUCL30387 cds-NP_012790.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:194584-195876:- gene-YKL132C_MUCL30388 rna-NM_001179698.1_MUCL30388 cds-NP_012790.1_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:192500-193792:- gene-YKL132C_MUCL39482 rna-NM_001179698.1_MUCL39482 cds-NP_012790.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:196894-198186:- gene-YKL132C_MUCL42920 rna-NM_001179698.1_MUCL42920 cds-NP_012790.1_MUCL42920 99.1 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:193563-194855:- gene-YKL132C_NCIM3186 rna-NM_001179698.1_NCIM3186 cds-NP_012790.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:192690-193982:- gene-YKL132C_NCYC1407 rna-NM_001179698.1_NCYC1407 cds-NP_012790.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:199813-201105:- gene-YKL132C_PE2H3 rna-NM_001179698.1_PE2H3 cds-NP_012790.1_PE2H3 99.1 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:196101-197393:- gene-YKL132C_PE2H4 rna-NM_001179698.1_PE2H4 cds-NP_012790.1_PE2H4 99.1 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:193574-194866:- gene-YKL132C_S288C rna-NM_001179698.1_S288C cds-NP_012790.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000008.1:110042-111334:- gene-YKL132C_SA1 rna-NM_001179698.1_SA1 cds-NP_012790.1_SA1 98.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:192715-194007:- gene-YKL132C_ThermosaccDry rna-NM_001179698.1_ThermosaccDry cds-NP_012790.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:192071-193363:- gene-YKL132C_VR1 rna-NM_001179698.1_VR1 cds-NP_012790.1_VR1 99.1 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:191247-192539:- gene-YKL132C_ZTW1 rna-NM_001179698.1_ZTW1 cds-NP_012790.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:207945-209240:- gene-YKL132C_Sparadoxus rna-NM_001179698.1_Sparadoxus cds-NP_012790.1_Sparadoxus 87.1 100.0 Verified 1 1 1 False True False False False

Additional files