RLI1 (YDR091C)


Gene profile

Gene name: RLI1
Reference locus (S288C): YDR091C
Gene biotype: protein_coding

Description: Translation initiation factor RLI1; Essential Fe-S protein; required for ribosome biogenesis, translation initiation/termination; facilitates binding of multifactor complex (MFC) of initiation factors to small ribosomal subunit; Dom34-Hbs1 complex and Rli1p work in dissociating inactive ribosomes, thereby facilitating translation restart; forms complex with Lto1p and Yae1p; dependency on ROS-labile FeS clusters, activity in nuclear ribosomal-subunit export impaired by mild oxidative stress

Top 10 interactors (score): PRT1 (0.999); HCR1 (0.999); ARX1 (0.999); RPG1 (0.999); NIP1 (0.999); SUP45 (0.999); DOM34 (0.999); TIF34 (0.998); ARB1 (0.998); ASC1 (0.997); SUI2 (0.997); RPS13 (0.997); YTM1 (0.996); RPS20 (0.996); RPS3 (0.995); RPS17A (0.995); TIF11 (0.995); HAS1 (0.995); NOG1 (0.994); RPS17B (0.993)

Homologues (species, bitscore): ABCE1 (Homo sapiens, 878.6); Abce1 (Mus musculus, 878.6); abce1 (Danio rerio, 885.6); abce1 (Xenopus tropicalis, 866.3); pix (Drosophila melanogaster, 859.0); abce-1 (Caenorhabditis elegans, 792.0); ABCE2 (Arabidopsis thaliana, 873.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:604261-606087:- gene-YDR091C_AKU4011 rna-NM_001180399.3_AKU4011 cds-NP_010376.3_AKU4011 99.7 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000080.1:519241-521067:+ gene-YDR091C_BG1 rna-NM_001180399.3_BG1 cds-NP_010376.3_BG1 99.9 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:636488-638314:- gene-YDR091C_Bruggeman rna-NM_001180399.3_Bruggeman cds-NP_010376.3_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:621182-623008:- gene-YDR091C_CAT1 rna-NM_001180399.3_CAT1 cds-NP_010376.3_CAT1 99.9 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:595282-597108:- gene-YDR091C_CBS1585 rna-NM_001180399.3_CBS1585 cds-NP_010376.3_CBS1585 99.7 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:620294-622120:- gene-YDR091C_CBS436 rna-NM_001180399.3_CBS436 cds-NP_010376.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:591694-593520:- gene-YDR091C_CBS6412 rna-NM_001180399.3_CBS6412 cds-NP_010376.3_CBS6412 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:620227-622053:- gene-YDR091C_CBS6413 rna-NM_001180399.3_CBS6413 cds-NP_010376.3_CBS6413 99.7 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:625747-627607:- gene-YDR091C_CENPK1137D rna-NM_001180399.3_CENPK1137D cds-NP_010376.3_CENPK1137D 97.6 100.0 Unannotated 1 1 0 False False False True False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:606052-607878:- gene-YDR091C_EthanolRed rna-NM_001180399.3_EthanolRed cds-NP_010376.3_EthanolRed 99.7 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:612846-614672:- gene-YDR091C_FaliES1 rna-NM_001180399.3_FaliES1 cds-NP_010376.3_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000358.1:16594-18420:+ gene-YDR091C_JAY291 rna-NM_001180399.3_JAY291 cds-NP_010376.3_JAY291 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:621107-622933:- gene-YDR091C_MUCL30387 rna-NM_001180399.3_MUCL30387 cds-NP_010376.3_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:611416-613242:- gene-YDR091C_MUCL30388 rna-NM_001180399.3_MUCL30388 cds-NP_010376.3_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:596652-598478:- gene-YDR091C_MUCL39482 rna-NM_001180399.3_MUCL39482 cds-NP_010376.3_MUCL39482 99.7 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:528107-529933:- gene-YDR091C_MUCL42920 rna-NM_001180399.3_MUCL42920 cds-NP_010376.3_MUCL42920 99.9 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:626631-628457:- gene-YDR091C_NCIM3186 rna-NM_001180399.3_NCIM3186 cds-NP_010376.3_NCIM3186 98.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:595559-597385:- gene-YDR091C_NCYC1407 rna-NM_001180399.3_NCYC1407 cds-NP_010376.3_NCYC1407 99.7 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:615026-616852:- gene-YDR091C_PE2H3 rna-NM_001180399.3_PE2H3 cds-NP_010376.3_PE2H3 99.9 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:614331-616157:- gene-YDR091C_PE2H4 rna-NM_001180399.3_PE2H4 cds-NP_010376.3_PE2H4 99.9 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:626708-628534:- gene-YDR091C_S288C rna-NM_001180399.3_S288C cds-NP_010376.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000011.1:16807-18633:+ gene-YDR091C_SA1 rna-NM_001180399.3_SA1 cds-NP_010376.3_SA1 99.9 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:612376-614202:- gene-YDR091C_ThermosaccDry rna-NM_001180399.3_ThermosaccDry cds-NP_010376.3_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:624926-626752:- gene-YDR091C_VR1 rna-NM_001180399.3_VR1 cds-NP_010376.3_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:609958-611784:- gene-YDR091C_ZTW1 rna-NM_001180399.3_ZTW1 cds-NP_010376.3_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:614397-616223:- gene-YDR091C_Sparadoxus rna-NM_001180399.3_Sparadoxus cds-NP_010376.3_Sparadoxus 93.8 100.0 Verified 1 1 1 False True False False False

Additional files