Gene name: RLF2
Reference locus (S288C): YPR018W
Gene biotype: protein_coding
Description: Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1); chromatin assembly by CAF-1 is important for multiple processes including silencing at telomeres, mating type loci, and rDNA; maintenance of kinetochore structure; deactivation of the DNA damage checkpoint after DNA repair; chromatin dynamics during transcription; and repression of divergent noncoding transcription
Top 10 interactors (score): CAC2 (0.999); MSI1 (0.999); ASF1 (0.997); HIR1 (0.993); RTT106 (0.989); HHT1 (0.971); HHT2 (0.966); POL30 (0.956); HHF1 (0.943); HIR2 (0.936); HPC2 (0.927); RTT109 (0.862); HIR3 (0.85); NCR1 (0.782); SAS4 (0.781); CYR1 (0.766); RRM3 (0.765); ACA1 (0.764); RAD53 (0.757); HMG2 (0.753)
Homologues (species, bitscore): CHAF1A (Homo sapiens, 87.0); chaf1a (Danio rerio, 97.4); Caf1-180 (Drosophila melanogaster, 94.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:566134-567951:+ | gene-YPR018W_AKU4011 | rna-NM_001184115.1_AKU4011 | cds-NP_015343.1_AKU4011 | 98.4 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:329180-330997:- | gene-YPR018W_BG1 | rna-NM_001184115.1_BG1 | cds-NP_015343.1_BG1 | 98.4 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:643795-645615:+ | gene-YPR018W_Bruggeman | rna-NM_001184115.1_Bruggeman | cds-NP_015343.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:687296-689113:+ | gene-YPR018W_CAT1 | rna-NM_001184115.1_CAT1 | cds-NP_015343.1_CAT1 | 98.9 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:569820-571637:+ | gene-YPR018W_CBS1585 | rna-NM_001184115.1_CBS1585 | cds-NP_015343.1_CBS1585 | 98.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:584190-586010:+ | gene-YPR018W_CBS436 | rna-NM_001184115.1_CBS436 | cds-NP_015343.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:573569-575386:+ | gene-YPR018W_CBS6412 | rna-NM_001184115.1_CBS6412 | cds-NP_015343.1_CBS6412 | 98.5 | 99.8 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:566283-568100:+ | gene-YPR018W_CBS6413 | rna-NM_001184115.1_CBS6413 | cds-NP_015343.1_CBS6413 | 98.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:594449-596269:+ | gene-YPR018W_CENPK1137D | rna-NM_001184115.1_CENPK1137D | cds-NP_015343.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:564069-565886:+ | gene-YPR018W_EthanolRed | rna-NM_001184115.1_EthanolRed | cds-NP_015343.1_EthanolRed | 98.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:571871-573688:+ | gene-YPR018W_FaliES1 | rna-NM_001184115.1_FaliES1 | cds-NP_015343.1_FaliES1 | 98.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000116.1:53749-55569:- | gene-YPR018W_JAY291 | rna-NM_001184115.1_JAY291 | cds-NP_015343.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:585015-586835:+ | gene-YPR018W_MUCL30387 | rna-NM_001184115.1_MUCL30387 | cds-NP_015343.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:583668-585488:+ | gene-YPR018W_MUCL30388 | rna-NM_001184115.1_MUCL30388 | cds-NP_015343.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:563061-564878:+ | gene-YPR018W_MUCL39482 | rna-NM_001184115.1_MUCL39482 | cds-NP_015343.1_MUCL39482 | 98.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:624392-626212:+ | gene-YPR018W_MUCL42920 | rna-NM_001184115.1_MUCL42920 | cds-NP_015343.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:594459-596279:+ | gene-YPR018W_NCIM3186 | rna-NM_001184115.1_NCIM3186 | cds-NP_015343.1_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:571008-572825:+ | gene-YPR018W_NCYC1407 | rna-NM_001184115.1_NCYC1407 | cds-NP_015343.1_NCYC1407 | 98.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:577741-579558:+ | gene-YPR018W_PE2H3 | rna-NM_001184115.1_PE2H3 | cds-NP_015343.1_PE2H3 | 98.4 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:577356-579173:+ | gene-YPR018W_PE2H4 | rna-NM_001184115.1_PE2H4 | cds-NP_015343.1_PE2H4 | 98.4 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:594476-596296:+ | gene-YPR018W_S288C | rna-NM_001184115.1_S288C | cds-NP_015343.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000026.1:104011-105831:- | gene-YPR018W_SA1 | rna-NM_001184115.1_SA1 | cds-NP_015343.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:571673-573490:+ | gene-YPR018W_ThermosaccDry | rna-NM_001184115.1_ThermosaccDry | cds-NP_015343.1_ThermosaccDry | 98.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:587909-589729:+ | gene-YPR018W_VR1 | rna-NM_001184115.1_VR1 | cds-NP_015343.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:570978-572795:+ | gene-YPR018W_ZTW1 | rna-NM_001184115.1_ZTW1 | cds-NP_015343.1_ZTW1 | 98.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:571154-572971:+ | gene-YPR018W_Sparadoxus | rna-NM_001184115.1_Sparadoxus | cds-NP_015343.1_Sparadoxus | 86.6 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |