RLF2 (YPR018W)


Gene profile

Gene name: RLF2
Reference locus (S288C): YPR018W
Gene biotype: protein_coding

Description: Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1); chromatin assembly by CAF-1 is important for multiple processes including silencing at telomeres, mating type loci, and rDNA; maintenance of kinetochore structure; deactivation of the DNA damage checkpoint after DNA repair; chromatin dynamics during transcription; and repression of divergent noncoding transcription

Top 10 interactors (score): CAC2 (0.999); MSI1 (0.999); ASF1 (0.997); HIR1 (0.993); RTT106 (0.989); HHT1 (0.971); HHT2 (0.966); POL30 (0.956); HHF1 (0.943); HIR2 (0.936); HPC2 (0.927); RTT109 (0.862); HIR3 (0.85); NCR1 (0.782); SAS4 (0.781); CYR1 (0.766); RRM3 (0.765); ACA1 (0.764); RAD53 (0.757); HMG2 (0.753)

Homologues (species, bitscore): CHAF1A (Homo sapiens, 87.0); chaf1a (Danio rerio, 97.4); Caf1-180 (Drosophila melanogaster, 94.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:566134-567951:+ gene-YPR018W_AKU4011 rna-NM_001184115.1_AKU4011 cds-NP_015343.1_AKU4011 98.4 99.8 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000091.1:329180-330997:- gene-YPR018W_BG1 rna-NM_001184115.1_BG1 cds-NP_015343.1_BG1 98.4 99.8 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:643795-645615:+ gene-YPR018W_Bruggeman rna-NM_001184115.1_Bruggeman cds-NP_015343.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:687296-689113:+ gene-YPR018W_CAT1 rna-NM_001184115.1_CAT1 cds-NP_015343.1_CAT1 98.9 99.8 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:569820-571637:+ gene-YPR018W_CBS1585 rna-NM_001184115.1_CBS1585 cds-NP_015343.1_CBS1585 98.5 99.8 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:584190-586010:+ gene-YPR018W_CBS436 rna-NM_001184115.1_CBS436 cds-NP_015343.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:573569-575386:+ gene-YPR018W_CBS6412 rna-NM_001184115.1_CBS6412 cds-NP_015343.1_CBS6412 98.5 99.8 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:566283-568100:+ gene-YPR018W_CBS6413 rna-NM_001184115.1_CBS6413 cds-NP_015343.1_CBS6413 98.6 99.8 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:594449-596269:+ gene-YPR018W_CENPK1137D rna-NM_001184115.1_CENPK1137D cds-NP_015343.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:564069-565886:+ gene-YPR018W_EthanolRed rna-NM_001184115.1_EthanolRed cds-NP_015343.1_EthanolRed 98.5 99.8 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:571871-573688:+ gene-YPR018W_FaliES1 rna-NM_001184115.1_FaliES1 cds-NP_015343.1_FaliES1 98.6 99.8 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000116.1:53749-55569:- gene-YPR018W_JAY291 rna-NM_001184115.1_JAY291 cds-NP_015343.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:585015-586835:+ gene-YPR018W_MUCL30387 rna-NM_001184115.1_MUCL30387 cds-NP_015343.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:583668-585488:+ gene-YPR018W_MUCL30388 rna-NM_001184115.1_MUCL30388 cds-NP_015343.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:563061-564878:+ gene-YPR018W_MUCL39482 rna-NM_001184115.1_MUCL39482 cds-NP_015343.1_MUCL39482 98.5 99.8 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:624392-626212:+ gene-YPR018W_MUCL42920 rna-NM_001184115.1_MUCL42920 cds-NP_015343.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:594459-596279:+ gene-YPR018W_NCIM3186 rna-NM_001184115.1_NCIM3186 cds-NP_015343.1_NCIM3186 98.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:571008-572825:+ gene-YPR018W_NCYC1407 rna-NM_001184115.1_NCYC1407 cds-NP_015343.1_NCYC1407 98.5 99.8 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:577741-579558:+ gene-YPR018W_PE2H3 rna-NM_001184115.1_PE2H3 cds-NP_015343.1_PE2H3 98.4 99.8 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:577356-579173:+ gene-YPR018W_PE2H4 rna-NM_001184115.1_PE2H4 cds-NP_015343.1_PE2H4 98.4 99.8 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:594476-596296:+ gene-YPR018W_S288C rna-NM_001184115.1_S288C cds-NP_015343.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000026.1:104011-105831:- gene-YPR018W_SA1 rna-NM_001184115.1_SA1 cds-NP_015343.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:571673-573490:+ gene-YPR018W_ThermosaccDry rna-NM_001184115.1_ThermosaccDry cds-NP_015343.1_ThermosaccDry 98.6 99.8 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:587909-589729:+ gene-YPR018W_VR1 rna-NM_001184115.1_VR1 cds-NP_015343.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:570978-572795:+ gene-YPR018W_ZTW1 rna-NM_001184115.1_ZTW1 cds-NP_015343.1_ZTW1 98.6 99.8 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:571154-572971:+ gene-YPR018W_Sparadoxus rna-NM_001184115.1_Sparadoxus cds-NP_015343.1_Sparadoxus 86.6 99.6 Verified 1 1 1 False True False False False

Additional files