Gene name: RIO1
Reference locus (S288C): YOR119C
Gene biotype: protein_coding
Description: Serine/threonine-protein kinase RIO1; Serine kinase involved in cell cycle regulation and rDNA integrity; associated with late pre-40S particles via its conserved C-terminal domain and participates in late 40S biogenesis; association with pre-40S particles regulated by its catalytic ATPase site and likely occurs after the release of Rio2p from these particles; involved in cell cycle progression and processing of the 20S pre-rRNA into mature 18S rRNA; phosphorylates Rpa43p in anaphase to remove Pol I from rDNA; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family
Top 10 interactors (score): NOB1 (0.999); RIO2 (0.997); HSL7 (0.996); PNO1 (0.995); TSR1 (0.988); ENP1 (0.977); LTV1 (0.96); NOC4 (0.958); FAP7 (0.943); BMS1 (0.941); NOP4 (0.94); SPB1 (0.936); RRP12 (0.933); KRE33 (0.926); UTP23 (0.924); PRP43 (0.923); PXR1 (0.92); NOP7 (0.917); SDA1 (0.917); ESF1 (0.917)
Homologues (species, bitscore): RIOK1 (Homo sapiens, 292.7); Riok1 (Mus musculus, 264.2); riok1 (Danio rerio, 295.0); riok1 (Xenopus tropicalis, 292.7); RIOK1 (Drosophila melanogaster, 282.7); riok-1 (Caenorhabditis elegans, 270.4); AT2G24990 (Arabidopsis thaliana, 283.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:532857-534311:- | gene-YOR119C_AKU4011 | rna-NM_001183538.3_AKU4011 | cds-NP_014762.3_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000171.1:44958-46412:+ | gene-YOR119C_BG1 | rna-NM_001183538.3_BG1 | cds-NP_014762.3_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:536405-537859:- | gene-YOR119C_Bruggeman | rna-NM_001183538.3_Bruggeman | cds-NP_014762.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:536409-537863:- | gene-YOR119C_CAT1 | rna-NM_001183538.3_CAT1 | cds-NP_014762.3_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:528420-529874:- | gene-YOR119C_CBS1585 | rna-NM_001183538.3_CBS1585 | cds-NP_014762.3_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:533129-534583:- | gene-YOR119C_CBS436 | rna-NM_001183538.3_CBS436 | cds-NP_014762.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:526906-528360:- | gene-YOR119C_CBS6412 | rna-NM_001183538.3_CBS6412 | cds-NP_014762.3_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:534202-535656:- | gene-YOR119C_CBS6413 | rna-NM_001183538.3_CBS6413 | cds-NP_014762.3_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:548872-550326:- | gene-YOR119C_CENPK1137D | rna-NM_001183538.3_CENPK1137D | cds-NP_014762.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:529225-530679:- | gene-YOR119C_EthanolRed | rna-NM_001183538.3_EthanolRed | cds-NP_014762.3_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:532920-534374:- | gene-YOR119C_FaliES1 | rna-NM_001183538.3_FaliES1 | cds-NP_014762.3_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000063.1:24891-26345:+ | gene-YOR119C_JAY291 | rna-NM_001183538.3_JAY291 | cds-NP_014762.3_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:540962-542416:- | gene-YOR119C_MUCL30387 | rna-NM_001183538.3_MUCL30387 | cds-NP_014762.3_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:546171-547625:- | gene-YOR119C_MUCL30388 | rna-NM_001183538.3_MUCL30388 | cds-NP_014762.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:535814-537268:- | gene-YOR119C_MUCL39482 | rna-NM_001183538.3_MUCL39482 | cds-NP_014762.3_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:551860-553314:- | gene-YOR119C_MUCL42920 | rna-NM_001183538.3_MUCL42920 | cds-NP_014762.3_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:548681-550135:- | gene-YOR119C_NCIM3186 | rna-NM_001183538.3_NCIM3186 | cds-NP_014762.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:542262-543716:- | gene-YOR119C_NCYC1407 | rna-NM_001183538.3_NCYC1407 | cds-NP_014762.3_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:541265-542719:- | gene-YOR119C_PE2H3 | rna-NM_001183538.3_PE2H3 | cds-NP_014762.3_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:551642-553096:- | gene-YOR119C_PE2H4 | rna-NM_001183538.3_PE2H4 | cds-NP_014762.3_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:548792-550246:- | gene-YOR119C_S288C | rna-NM_001183538.3_S288C | cds-NP_014762.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000034.1:78333-79787:- | gene-YOR119C_SA1 | rna-NM_001183538.3_SA1 | cds-NP_014762.3_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:532104-533558:- | gene-YOR119C_ThermosaccDry | rna-NM_001183538.3_ThermosaccDry | cds-NP_014762.3_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:534210-535664:- | gene-YOR119C_VR1 | rna-NM_001183538.3_VR1 | cds-NP_014762.3_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:266042-267496:- | gene-YOR119C_ZTW1 | rna-NM_001183538.3_ZTW1 | cds-NP_014762.3_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:538058-539521:- | gene-YOR119C_Sparadoxus | rna-NM_001183538.3_Sparadoxus | cds-NP_014762.3_Sparadoxus | 90.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |