Gene name: RIM11
Reference locus (S288C): YMR139W
Gene biotype: protein_coding
Description: Serine/threonine-protein kinase RIM11/MSD1; Protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication
Top 10 interactors (score): IME1 (0.986); UME6 (0.974); SKN7 (0.959); HSF1 (0.942); NAP1 (0.917); MGA1 (0.912); HMS2 (0.91); HSC82 (0.864); CMD1 (0.843); HRR25 (0.831); HSP82 (0.829); MCK1 (0.813); ACT1 (0.811); BMH1 (0.786); CUL3 (0.781); YCK2 (0.777); BMH2 (0.777); TEP1 (0.768); RIM15 (0.767); YCK1 (0.75)
Homologues (species, bitscore): GSK3A (Homo sapiens, 374.0); Gsk3b (Mus musculus, 375.6); gsk3bb (Danio rerio, 380.2); gsk3a (Xenopus tropicalis, 376.3); sgg (Drosophila melanogaster, 367.9); gsk-3 (Caenorhabditis elegans, 374.4); SK32 (Arabidopsis thaliana, 368.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:585622-586734:+ | gene-YMR139W_AKU4011 | rna-NM_001182641.1_AKU4011 | cds-NP_013859.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000068.1:85797-86909:- | gene-YMR139W_BG1 | rna-NM_001182641.1_BG1 | cds-NP_013859.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:528805-529917:+ | gene-YMR139W_Bruggeman | rna-NM_001182641.1_Bruggeman | cds-NP_013859.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:531020-532132:+ | gene-YMR139W_CAT1 | rna-NM_001182641.1_CAT1 | cds-NP_013859.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:518546-519658:+ | gene-YMR139W_CBS1585 | rna-NM_001182641.1_CBS1585 | cds-NP_013859.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:522435-523547:+ | gene-YMR139W_CBS436 | rna-NM_001182641.1_CBS436 | cds-NP_013859.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:631539-632651:+ | gene-YMR139W_CBS6412 | rna-NM_001182641.1_CBS6412 | cds-NP_013859.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:517106-518218:+ | gene-YMR139W_CBS6413 | rna-NM_001182641.1_CBS6413 | cds-NP_013859.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:540644-541756:+ | gene-YMR139W_CENPK1137D | rna-NM_001182641.1_CENPK1137D | cds-NP_013859.1_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:516734-517846:+ | gene-YMR139W_EthanolRed | rna-NM_001182641.1_EthanolRed | cds-NP_013859.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:523733-524845:+ | gene-YMR139W_FaliES1 | rna-NM_001182641.1_FaliES1 | cds-NP_013859.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000294.1:3200-4312:- | gene-YMR139W_JAY291 | rna-NM_001182641.1_JAY291 | cds-NP_013859.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:523530-524642:+ | gene-YMR139W_MUCL30387 | rna-NM_001182641.1_MUCL30387 | cds-NP_013859.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:529062-530174:+ | gene-YMR139W_MUCL30388 | rna-NM_001182641.1_MUCL30388 | cds-NP_013859.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:519247-520359:+ | gene-YMR139W_MUCL39482 | rna-NM_001182641.1_MUCL39482 | cds-NP_013859.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:525541-526653:+ | gene-YMR139W_MUCL42920 | rna-NM_001182641.1_MUCL42920 | cds-NP_013859.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:546079-547191:+ | gene-YMR139W_NCIM3186 | rna-NM_001182641.1_NCIM3186 | cds-NP_013859.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:518885-519997:+ | gene-YMR139W_NCYC1407 | rna-NM_001182641.1_NCYC1407 | cds-NP_013859.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:529322-530434:+ | gene-YMR139W_PE2H3 | rna-NM_001182641.1_PE2H3 | cds-NP_013859.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:529781-530893:+ | gene-YMR139W_PE2H4 | rna-NM_001182641.1_PE2H4 | cds-NP_013859.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:546125-547237:+ | gene-YMR139W_S288C | rna-NM_001182641.1_S288C | cds-NP_013859.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000048.1:24032-25144:- | gene-YMR139W_SA1 | rna-NM_001182641.1_SA1 | cds-NP_013859.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:519132-520244:+ | gene-YMR139W_ThermosaccDry | rna-NM_001182641.1_ThermosaccDry | cds-NP_013859.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:531835-532947:+ | gene-YMR139W_VR1 | rna-NM_001182641.1_VR1 | cds-NP_013859.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:494276-495388:+ | gene-YMR139W_ZTW1 | rna-NM_001182641.1_ZTW1 | cds-NP_013859.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:530568-531680:+ | gene-YMR139W_Sparadoxus | rna-NM_001182641.1_Sparadoxus | cds-NP_013859.1_Sparadoxus | 91.4 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |