RIF2 (YLR453C)


Gene profile

Gene name: RIF2
Reference locus (S288C): YLR453C
Gene biotype: protein_coding

Description: Protein that binds to the Rap1p C-terminus; acts synergistically with Rif1p to help control telomere length and establish telomeric silencing; deletion results in telomere elongation; RIF2 has a paralog, ORC4, that arose from the whole genome duplication

Top 10 interactors (score): RAP1 (0.999); RIF1 (0.998); CDC13 (0.99); TEL1 (0.962); YKU70 (0.96); TEN1 (0.955); STN1 (0.934); SIR4 (0.922); EST1 (0.896); SIR3 (0.891); EXO1 (0.856); YKU80 (0.849); PIF1 (0.849); TBF1 (0.832); RAD50 (0.82); NSE3 (0.78); SGS1 (0.775); EST3 (0.767); MEC1 (0.746); SIR2 (0.731)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:980089-981276:- gene-YLR453C_AKU4011 rna-NM_001182341.3_AKU4011 cds-NP_013558.3_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000048.1:212527-213714:- gene-YLR453C_BG1 rna-NM_001182341.3_BG1 cds-NP_013558.3_BG1 99.1 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:1018385-1019572:- gene-YLR453C_Bruggeman rna-NM_001182341.3_Bruggeman cds-NP_013558.3_Bruggeman 99.2 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:1014392-1015579:- gene-YLR453C_CAT1 rna-NM_001182341.3_CAT1 cds-NP_013558.3_CAT1 99.1 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:1015679-1016866:- gene-YLR453C_CBS1585 rna-NM_001182341.3_CBS1585 cds-NP_013558.3_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:1005006-1006193:- gene-YLR453C_CBS436 rna-NM_001182341.3_CBS436 cds-NP_013558.3_CBS436 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:1051708-1052895:- gene-YLR453C_CBS6412 rna-NM_001182341.3_CBS6412 cds-NP_013558.3_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:1016449-1017636:- gene-YLR453C_CBS6413 rna-NM_001182341.3_CBS6413 cds-NP_013558.3_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:1026425-1027612:- gene-YLR453C_CENPK1137D rna-NM_001182341.3_CENPK1137D cds-NP_013558.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:973105-974292:- gene-YLR453C_EthanolRed rna-NM_001182341.3_EthanolRed cds-NP_013558.3_EthanolRed 99.0 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:1008376-1009563:- gene-YLR453C_FaliES1 rna-NM_001182341.3_FaliES1 cds-NP_013558.3_FaliES1 99.0 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000194.1:9112-10299:+ gene-YLR453C_JAY291 rna-NM_001182341.3_JAY291 cds-NP_013558.3_JAY291 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:1017242-1018429:- gene-YLR453C_MUCL30387 rna-NM_001182341.3_MUCL30387 cds-NP_013558.3_MUCL30387 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:1027075-1028262:- gene-YLR453C_MUCL30388 rna-NM_001182341.3_MUCL30388 cds-NP_013558.3_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:1016913-1018100:- gene-YLR453C_MUCL39482 rna-NM_001182341.3_MUCL39482 cds-NP_013558.3_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:1017366-1018553:- gene-YLR453C_MUCL42920 rna-NM_001182341.3_MUCL42920 cds-NP_013558.3_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:1041773-1042960:- gene-YLR453C_NCIM3186 rna-NM_001182341.3_NCIM3186 cds-NP_013558.3_NCIM3186 95.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:1026350-1027537:- gene-YLR453C_NCYC1407 rna-NM_001182341.3_NCYC1407 cds-NP_013558.3_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:1012796-1013983:- gene-YLR453C_PE2H3 rna-NM_001182341.3_PE2H3 cds-NP_013558.3_PE2H3 99.2 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:1012540-1013727:- gene-YLR453C_PE2H4 rna-NM_001182341.3_PE2H4 cds-NP_013558.3_PE2H4 99.2 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:1041799-1042986:- gene-YLR453C_S288C rna-NM_001182341.3_S288C cds-NP_013558.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000007.1:16875-18062:+ gene-YLR453C_SA1 rna-NM_001182341.3_SA1 cds-NP_013558.3_SA1 99.1 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:1011454-1012641:- gene-YLR453C_ThermosaccDry rna-NM_001182341.3_ThermosaccDry cds-NP_013558.3_ThermosaccDry 99.0 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:1017877-1019064:- gene-YLR453C_VR1 rna-NM_001182341.3_VR1 cds-NP_013558.3_VR1 99.1 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000025.1:341707-342894:- gene-YLR453C_ZTW1 rna-NM_001182341.3_ZTW1 cds-NP_013558.3_ZTW1 99.1 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:990655-991842:- gene-YLR453C_Sparadoxus rna-NM_001182341.3_Sparadoxus cds-NP_013558.3_Sparadoxus 82.3 99.8 Verified 1 1 1 False True False False False

Additional files