RIB2 (YOL066C)


Gene profile

Gene name: RIB2
Reference locus (S288C): YOL066C
Gene biotype: protein_coding

Description: Bifunctional protein RIB2; Bifunctional DRAP deaminase tRNA:pseudouridine synthase; the deaminase catalyzes the third step in riboflavin biosynthesis and the synthase catalyzes formation of pseudouridine at position 32 in cytoplasmic tRNAs; RIB2 has a paralog, PUS9, that arose from the whole genome duplication

Top 10 interactors (score): RIB7 (0.991); TAD3 (0.977); PUS7 (0.963); PUS2 (0.941); RIB3 (0.939); PUS4 (0.936); RIB5 (0.929); RIB1 (0.918); CDD1 (0.912); PUS1 (0.904); TAD1 (0.891); DEG1 (0.891); DCD1 (0.878); MSS1 (0.861); PUS5 (0.86); ERV1 (0.86); TAD2 (0.858); FCY1 (0.79); RIB4 (0.776); FAD1 (0.77)

Homologues (species, bitscore): RPUSD2 (Homo sapiens, 280.8); Rpusd2 (Mus musculus, 281.6); LOC565088 (Danio rerio, 274.2); rpusd2 (Xenopus tropicalis, 265.4); RluA-2 (Drosophila melanogaster, 274.6); K07E8.7 (Caenorhabditis elegans, 196.8); AT5G51140 (Arabidopsis thaliana, 203.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:186350-188125:- gene-YOL066C_AKU4011 rna-NM_001183321.1_AKU4011 cds-NP_014575.1_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000152.1:2303-4078:- gene-YOL066C_BG1 rna-NM_001183321.1_BG1 cds-NP_014575.1_BG1 99.2 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:188020-189795:- gene-YOL066C_Bruggeman rna-NM_001183321.1_Bruggeman cds-NP_014575.1_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:187532-189307:- gene-YOL066C_CAT1 rna-NM_001183321.1_CAT1 cds-NP_014575.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:180741-182516:- gene-YOL066C_CBS1585 rna-NM_001183321.1_CBS1585 cds-NP_014575.1_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:185900-187675:- gene-YOL066C_CBS436 rna-NM_001183321.1_CBS436 cds-NP_014575.1_CBS436 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:180670-182445:- gene-YOL066C_CBS6412 rna-NM_001183321.1_CBS6412 cds-NP_014575.1_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:187606-189381:- gene-YOL066C_CBS6413 rna-NM_001183321.1_CBS6413 cds-NP_014575.1_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:202446-204221:- gene-YOL066C_CENPK1137D rna-NM_001183321.1_CENPK1137D cds-NP_014575.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:183450-185225:- gene-YOL066C_EthanolRed rna-NM_001183321.1_EthanolRed cds-NP_014575.1_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:185993-187768:- gene-YOL066C_FaliES1 rna-NM_001183321.1_FaliES1 cds-NP_014575.1_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000018.1:77789-79564:+ gene-YOL066C_JAY291 rna-NM_001183321.1_JAY291 cds-NP_014575.1_JAY291 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:191785-193560:- gene-YOL066C_MUCL30387 rna-NM_001183321.1_MUCL30387 cds-NP_014575.1_MUCL30387 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:195469-197244:- gene-YOL066C_MUCL30388 rna-NM_001183321.1_MUCL30388 cds-NP_014575.1_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:188661-190436:- gene-YOL066C_MUCL39482 rna-NM_001183321.1_MUCL39482 cds-NP_014575.1_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:204142-205917:- gene-YOL066C_MUCL42920 rna-NM_001183321.1_MUCL42920 cds-NP_014575.1_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:202585-204360:- gene-YOL066C_NCIM3186 rna-NM_001183321.1_NCIM3186 cds-NP_014575.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:195278-197053:- gene-YOL066C_NCYC1407 rna-NM_001183321.1_NCYC1407 cds-NP_014575.1_NCYC1407 99.2 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:178284-180059:- gene-YOL066C_PE2H3 rna-NM_001183321.1_PE2H3 cds-NP_014575.1_PE2H3 99.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:189274-191049:- gene-YOL066C_PE2H4 rna-NM_001183321.1_PE2H4 cds-NP_014575.1_PE2H4 99.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:202696-204471:- gene-YOL066C_S288C rna-NM_001183321.1_S288C cds-NP_014575.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000001.1:170584-172359:- gene-YOL066C_SA1 rna-NM_001183321.1_SA1 cds-NP_014575.1_SA1 99.0 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:185001-186776:- gene-YOL066C_ThermosaccDry rna-NM_001183321.1_ThermosaccDry cds-NP_014575.1_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:185764-187539:- gene-YOL066C_VR1 rna-NM_001183321.1_VR1 cds-NP_014575.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000031.1:184645-186420:- gene-YOL066C_ZTW1 rna-NM_001183321.1_ZTW1 cds-NP_014575.1_ZTW1 99.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:188181-189956:- gene-YOL066C_Sparadoxus rna-NM_001183321.1_Sparadoxus cds-NP_014575.1_Sparadoxus 89.2 99.8 Verified 1 1 1 False True False False False

Additional files