RIA1 (YNL163C)


Gene profile

Gene name: RIA1
Reference locus (S288C): YNL163C
Gene biotype: protein_coding

Description: Ribosome assembly protein 1; Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis; with Sdo1p, a guanine nucleotide exchange factor (GEF), promotes release of Tif6p from 60S ribosomal subunits in the cytoplasm so that they can assemble with 40S subunits to generate mature ribosomes; required for quality control check of newly made large ribosomal subunits before they are released into the pool of translating ribosomes

Top 10 interactors (score): SDO1 (0.999); TIF6 (0.991); LSG1 (0.957); RPL5 (0.944); RLP24 (0.937); NMD3 (0.936); RPL10 (0.923); REI1 (0.878); RPL25 (0.875); NOG1 (0.872); TEF4 (0.856); CAM1 (0.856); MRT4 (0.856); RPP0 (0.855); ARX1 (0.848); AFG2 (0.829); PRP8 (0.828); RRP12 (0.82); RPS3 (0.817); DIP2 (0.816)

Homologues (species, bitscore): EFTUD1 (Homo sapiens, 778.9); Eftud1 (Mus musculus, 781.6); EFTUD1 (Danio rerio, 808.5); EFTUD1 (Xenopus tropicalis, 760.4); CG33158 (Drosophila melanogaster, 711.8); K10C3.5 (Caenorhabditis elegans, 414.8); AT3G22980 (Arabidopsis thaliana, 632.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:320471-323803:- gene-YNL163C_AKU4011 rna-NM_001183001.1_AKU4011 cds-NP_014236.1_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:224435-227767:- gene-YNL163C_BG1 rna-NM_001183001.1_BG1 cds-NP_014236.1_BG1 99.8 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:330527-333859:- gene-YNL163C_Bruggeman rna-NM_001183001.1_Bruggeman cds-NP_014236.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:373404-376736:- gene-YNL163C_CAT1 rna-NM_001183001.1_CAT1 cds-NP_014236.1_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:321123-324455:- gene-YNL163C_CBS1585 rna-NM_001183001.1_CBS1585 cds-NP_014236.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:389442-392774:- gene-YNL163C_CBS436 rna-NM_001183001.1_CBS436 cds-NP_014236.1_CBS436 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:316528-319860:- gene-YNL163C_CBS6412 rna-NM_001183001.1_CBS6412 cds-NP_014236.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:317556-320888:- gene-YNL163C_CBS6413 rna-NM_001183001.1_CBS6413 cds-NP_014236.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:320555-323887:- gene-YNL163C_CENPK1137D rna-NM_001183001.1_CENPK1137D cds-NP_014236.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:317444-320776:- gene-YNL163C_EthanolRed rna-NM_001183001.1_EthanolRed cds-NP_014236.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:313357-316689:- gene-YNL163C_FaliES1 rna-NM_001183001.1_FaliES1 cds-NP_014236.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000260.1:1811-5143:+ gene-YNL163C_JAY291 rna-NM_001183001.1_JAY291 cds-NP_014236.1_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:326347-329679:- gene-YNL163C_MUCL30387 rna-NM_001183001.1_MUCL30387 cds-NP_014236.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:360901-364233:- gene-YNL163C_MUCL30388 rna-NM_001183001.1_MUCL30388 cds-NP_014236.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:318362-321694:- gene-YNL163C_MUCL39482 rna-NM_001183001.1_MUCL39482 cds-NP_014236.1_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:320765-324097:- gene-YNL163C_MUCL42920 rna-NM_001183001.1_MUCL42920 cds-NP_014236.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:326710-330042:- gene-YNL163C_NCIM3186 rna-NM_001183001.1_NCIM3186 cds-NP_014236.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:320456-323788:- gene-YNL163C_NCYC1407 rna-NM_001183001.1_NCYC1407 cds-NP_014236.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:317413-320745:- gene-YNL163C_PE2H3 rna-NM_001183001.1_PE2H3 cds-NP_014236.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:316801-320133:- gene-YNL163C_PE2H4 rna-NM_001183001.1_PE2H4 cds-NP_014236.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:326741-330073:- gene-YNL163C_S288C rna-NM_001183001.1_S288C cds-NP_014236.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000018.1:83500-86832:+ gene-YNL163C_SA1 rna-NM_001183001.1_SA1 cds-NP_014236.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:314214-317546:- gene-YNL163C_ThermosaccDry rna-NM_001183001.1_ThermosaccDry cds-NP_014236.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:332736-336068:- gene-YNL163C_VR1 rna-NM_001183001.1_VR1 cds-NP_014236.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:224037-227369:- gene-YNL163C_ZTW1 rna-NM_001183001.1_ZTW1 cds-NP_014236.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:324819-328151:- gene-YNL163C_Sparadoxus rna-NM_001183001.1_Sparadoxus cds-NP_014236.1_Sparadoxus 90.3 100.0 Verified 1 1 1 False True False False False

Additional files