RHO5 (YNL180C)


Gene profile

Gene name: RHO5
Reference locus (S288C): YNL180C
Gene biotype: protein_coding

Description: GTP-binding protein RHO5; Non-essential small GTPase of the Rho/Rac family of Ras-like proteins; RAC1 ortholog; regulated by phosphorylation and ubiquitination; likely involved in protein kinase C (Pkc1p)-dependent signal transduction pathway that controls cell integrity

Top 10 interactors (score): BZZ1 (0.967); BAG7 (0.96); ECM25 (0.955); BUD5 (0.944); CDC25 (0.944); SAC7 (0.943); RDI1 (0.927); DCK1 (0.917); PKC1 (0.915); FUS2 (0.9); PAN1 (0.9); END3 (0.9); ROM1 (0.873); LMO1 (0.863); RGD2 (0.861); RGD1 (0.847); LAS17 (0.843); PRR2 (0.816); GPA2 (0.79); NCE102 (0.786)

Homologues (species, bitscore): CDC42 (Homo sapiens, 198.4); Cdc42 (Mus musculus, 198.4); cdc42 (Danio rerio, 199.9); cdc42 (Xenopus tropicalis, 199.9); Cdc42 (Drosophila melanogaster, 196.1); cdc-42 (Caenorhabditis elegans, 200.3); RAC2 (Arabidopsis thaliana, 175.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:293404-294399:- gene-YNL180C_AKU4011 rna-NM_001183018.1_AKU4011 cds-NP_014219.1_AKU4011 99.0 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:197380-198375:- gene-YNL180C_BG1 rna-NM_001183018.1_BG1 cds-NP_014219.1_BG1 99.8 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:303437-304432:- gene-YNL180C_Bruggeman rna-NM_001183018.1_Bruggeman cds-NP_014219.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:345731-346726:- gene-YNL180C_CAT1 rna-NM_001183018.1_CAT1 cds-NP_014219.1_CAT1 99.7 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:294047-295042:- gene-YNL180C_CBS1585 rna-NM_001183018.1_CBS1585 cds-NP_014219.1_CBS1585 99.0 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:362356-363351:- gene-YNL180C_CBS436 rna-NM_001183018.1_CBS436 cds-NP_014219.1_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:289461-290456:- gene-YNL180C_CBS6412 rna-NM_001183018.1_CBS6412 cds-NP_014219.1_CBS6412 99.0 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:290480-291475:- gene-YNL180C_CBS6413 rna-NM_001183018.1_CBS6413 cds-NP_014219.1_CBS6413 99.0 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:293482-294477:- gene-YNL180C_CENPK1137D rna-NM_001183018.1_CENPK1137D cds-NP_014219.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:290379-291374:- gene-YNL180C_EthanolRed rna-NM_001183018.1_EthanolRed cds-NP_014219.1_EthanolRed 98.9 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:286292-287287:- gene-YNL180C_FaliES1 rna-NM_001183018.1_FaliES1 cds-NP_014219.1_FaliES1 98.8 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000260.1:31235-32230:+ gene-YNL180C_JAY291 rna-NM_001183018.1_JAY291 cds-NP_014219.1_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:299252-300247:- gene-YNL180C_MUCL30387 rna-NM_001183018.1_MUCL30387 cds-NP_014219.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:333570-334565:- gene-YNL180C_MUCL30388 rna-NM_001183018.1_MUCL30388 cds-NP_014219.1_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:291286-292281:- gene-YNL180C_MUCL39482 rna-NM_001183018.1_MUCL39482 cds-NP_014219.1_MUCL39482 99.0 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:293676-294671:- gene-YNL180C_MUCL42920 rna-NM_001183018.1_MUCL42920 cds-NP_014219.1_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:299623-300618:- gene-YNL180C_NCIM3186 rna-NM_001183018.1_NCIM3186 cds-NP_014219.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:293380-294375:- gene-YNL180C_NCYC1407 rna-NM_001183018.1_NCYC1407 cds-NP_014219.1_NCYC1407 99.0 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:290324-291319:- gene-YNL180C_PE2H3 rna-NM_001183018.1_PE2H3 cds-NP_014219.1_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:289712-290707:- gene-YNL180C_PE2H4 rna-NM_001183018.1_PE2H4 cds-NP_014219.1_PE2H4 99.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:299654-300649:- gene-YNL180C_S288C rna-NM_001183018.1_S288C cds-NP_014219.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000018.1:112957-113952:+ gene-YNL180C_SA1 rna-NM_001183018.1_SA1 cds-NP_014219.1_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:287149-288144:- gene-YNL180C_ThermosaccDry rna-NM_001183018.1_ThermosaccDry cds-NP_014219.1_ThermosaccDry 98.9 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:305648-306643:- gene-YNL180C_VR1 rna-NM_001183018.1_VR1 cds-NP_014219.1_VR1 99.8 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:196977-197972:- gene-YNL180C_ZTW1 rna-NM_001183018.1_ZTW1 cds-NP_014219.1_ZTW1 99.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:297704-298699:- gene-YNL180C_Sparadoxus rna-NM_001183018.1_Sparadoxus cds-NP_014219.1_Sparadoxus 92.5 99.7 Verified 1 1 1 False True False False False

Additional files